{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T03:20:47Z","timestamp":1787887247911,"version":"build-2784847793"},"reference-count":30,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ajvr"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"s001\">\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To compare initial leak pressure (ILP) between cadaveric canine and synthetic small intestinal segments that did and did not undergo enterotomy.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s002\">\n<jats:title>SAMPLE<\/jats:title>\n<jats:p>Eight 8-cm grossly normal jejunal segments from 1 canine cadaver and eight 8-cm synthetic small intestinal segments.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s003\">\n<jats:title>PROCEDURES<\/jats:title>\n<jats:p>Intestinal segments were randomly assigned to undergo enterotomy (6 cadaveric and 6 synthetic segments) or serve as untreated controls (2 cadaveric and 2 synthetic segments). For segments designated for enterotomy, a 2-cm full-thickness incision was created along the antimesenteric border. The incision was closed in a single layer with 4-0 suture in a simple continuous pattern. Leak testing was performed with intestinal segments occluded at both ends and infused with dilute dye solution (999 mL\/h) until the solution was observed leaking from the suture line or serosal tearing occurred. Intraluminal pressure was continuously monitored. The ILP at construct failure was compared between cadaveric and synthetic control segments and between cadaveric and synthetic enterotomy segments.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s004\">\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Mean \u00b1 SD ILP did not differ significantly between cadaveric (345.11 \u00b1 2.15 mm Hg) and synthetic (329.04 \u00b1 24.69 mm Hg) control segments but was significantly greater for cadaveric enterotomy segments (60.77 \u00b1 15.81 mm Hg), compared with synthetic enterotomy segments (15.03 \u00b1 6.41 mm Hg).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s005\">\n<jats:title>CONCLUSIONS AND CLINICAL RELEVANCE<\/jats:title>\n<jats:p>Leak testing should not be used to assess the accuracy or security of enterotomy suture lines in synthetic intestinal tissue. Synthetic intestinal tissue is best used for students to gain confidence and proficiency in performing enterotomies before performing the procedure on live animals.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/ajvr.81.10.827","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T12:37:59Z","timestamp":1600951079000},"page":"827-831","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of intestinal leak pressure between cadaveric canine and commercial synthetic intestinal tissue that did and did not undergo enterotomy"],"prefix":"10.2460","volume":"81","author":[{"given":"Penny J.","family":"Regier","sequence":"first","affiliation":[{"name":"1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Fealey","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley E.","family":"Kim","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Brad","family":"Case","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Garcia-Pereira","sequence":"additional","affiliation":[{"name":"1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"The principles of humane experimental technique","author":"Russell","year":"1959"},{"key":"ref2","series-title":"J Vet Med Educ","doi-asserted-by":"publisher","first-page":"473","DOI":"10.3138\/jvme.32.4.473","article-title":"Mainstreaming alternatives in veterinary medical education: resource development and curricular reform","volume":"32","author":"Hart","year":"2005"},{"key":"ref3","series-title":"J Vet Med 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