{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T04:02:32Z","timestamp":1763179352873},"reference-count":22,"publisher":"American Veterinary Medical Association (AVMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2021,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec id=\"s001\">\n<jats:title>CASE DESCRIPTION<\/jats:title>\n<jats:p>An 11-year-old sexually intact male Shih Tzu diagnosed with acute kidney injury and left-sided congestive heart failure that had nonelective mitral valve surgery.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s002\">\n<jats:title>CLINICAL FINDINGS<\/jats:title>\n<jats:p>Metabolic alkalosis developed postoperatively, and plasma bicarbonate concentration peaked 2 days after surgery (40.2 mmol\/L; pH, 7.550).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s003\">\n<jats:title>TREATMENT AND OUTCOME<\/jats:title>\n<jats:p>Acetazolamide administration increased the urinary excretion of bicarbonate and contributed to the improvement of the dog\u2019s acid-base status and oxygenation capacity. Metabolic alkalosis persisted for 4 days after surgery, and no treatment was required after resolution. Plasma urea nitrogen and creatinine concentrations normalized 2 days after surgery.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"s004\">\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>Severe metabolic alkalosis can occur as a complication following mitral valve surgery. Acetazolamide may be suitable for the treatment of severe metabolic alkalosis.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.20.09.0519","type":"journal-article","created":{"date-parts":[[2021,11,4]],"date-time":"2021-11-04T18:52:40Z","timestamp":1636051960000},"page":"1332-1336","source":"Crossref","is-referenced-by-count":6,"title":["Metabolic alkalosis following mitral valvuloplasty in a dog with preoperative acute kidney injury"],"prefix":"10.2460","volume":"259","author":[{"given":"Katsuhiro","family":"Matsuura","sequence":"first","affiliation":[{"name":"From the VCA Japan Shiraishi Animal Hospital, Saitama, Japan."},{"name":"From the Department of Veterinary Surgery, Tokyo University of Agriculture and Technology, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiko","family":"Yoshida","sequence":"additional","affiliation":[{"name":"From the VCA Japan Shiraishi Animal Hospital, Saitama, Japan."},{"name":"From the Department of Veterinary Surgery, Tokyo University of Agriculture and Technology, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuya","family":"Uehara","sequence":"additional","affiliation":[{"name":"From the VCA Japan Shiraishi Animal Hospital, Saitama, Japan."},{"name":"From the Laboratory of Surgery 1, School of Veterinary Medicine, Azabu University, Kanagawa, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shusaku","family":"Yamada","sequence":"additional","affiliation":[{"name":"From the VCA Japan Shiraishi Animal Hospital, Saitama, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Yotsuida","sequence":"additional","affiliation":[{"name":"From the VCA Japan Shiraishi Animal Hospital, Saitama, Japan."},{"name":"From the Department of Clinical Engineering, National Cerebral and Cardiovascular Center, Osaka, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mizuki","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"From the VCA Japan Shiraishi Animal Hospital, Saitama, Japan."},{"name":"From the Laboratory of Surgery 1, School of Veterinary Medicine, Azabu University, Kanagawa, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakie","family":"Katayose","sequence":"additional","affiliation":[{"name":"From the VCA Japan Shiraishi Animal Hospital, Saitama, Japan."},{"name":"From the Laboratory of Surgery 1, School of Veterinary Medicine, Azabu University, Kanagawa, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurumi","family":"Yamada","sequence":"additional","affiliation":[{"name":"From the VCA Japan Shiraishi Animal Hospital, Saitama, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youta","family":"Yaginuma","sequence":"additional","affiliation":[{"name":"From the VCA Japan Shiraishi Animal Hospital, Saitama, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Proceedings of the Sixth Asian Meeting of Veterinary Medicine Specialties","first-page":"243","article-title":"Mitral annular dynamics short term after mitral valve surgery","author":"Matsuura K","year":"2019","unstructured":"Matsuura K, Hasegawa M, Shiraishi K,  Mitral annular dynamics short term after mitral valve surgery. 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