{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:54:19Z","timestamp":1791266059680,"version":"4.1.0"},"reference-count":24,"publisher":"American Veterinary Medical Association (AVMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2000,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To determine prevalence of pituitary\ntumors, detectable by means of computed tomography\nor magnetic resonance imaging, in cats with\ninsulin resistance suspected to have acromegaly or\nhyperadrenocorticism versus cats with well-controlled\ndiabetes mellitus.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Case series.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201416 cats with insulin resistance that were\nalso suspected to have acromegaly (n = 12) or pituitary-dependent hyperadrenocorticism (4) and 8 cats\nwith well-controlled diabetes mellitus.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Computed tomography was performed\non all 16 cats with insulin resistance and 2 cats in\nwhich diabetes mellitus was well-controlled. The\nremaining 6 cats in which diabetes mellitus was wellcontrolled\nunderwent magnetic resonance imaging.\nImages were obtained before and immediately after\nIV administration of contrast medium.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014Computed tomography revealed a mass in\nthe region of the pituitary gland in all 16 cats with\ninsulin resistance. Maximum width of the masses\nranged from 4.4 to 12.7 mm; maximum height ranged\nfrom 3.1 to 12.6 mm. Results of computed tomography\nperformed on 2 cats with well-controlled diabetes\nand magnetic resonance imaging performed on the\nremaining 6 cats were considered normal.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results suggest\nthat cats with insulin resistance suspected to\nhave acromegaly or pituitary-dependent hyperadrenocorticism\nare likely to have a pituitary mass detectable\nby means of computed tomography or magnetic resonance\nimaging. 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