{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T15:40:14Z","timestamp":1789746014949,"version":"4.0.1"},"reference-count":12,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2000,11,15]]},"abstract":"Abstract<\/jats:title>\n\t\t\t\t\n\t\t\t\t\tObjective<\/jats:bold>\u2014To evaluate use of lufenuron for treating\ncutaneous fungal infections in dogs and cats.<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tDesign<\/jats:bold>\u2014Retrospective study.<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tAnimals<\/jats:bold>\u2014156 dogs and 201 cats with dermatophytosis\nor superficial dermatomycoses.<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tProcedure<\/jats:bold>\u2014Medical records were reviewed for dogs\nand cats that had been treated for dermatophytosis or\nother fungal infections by administration of lufenuron\nand 18 dogs and 42 cats that were not treated and\nserved as a control group.<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tResults<\/jats:bold>\u2014Dogs were treated once by oral administration\nof lufenuron tablets at doses ranging from\n54.2 to 68.3 mg\/kg (24.6 to 31.0 mg\/lb) of body\nweight. Samples of skin, scrapings, and hair were\nobtained daily from 14 dogs with dermatophytosis;\nmean durations from time of treatment to time of\nnegative fungal culture results and resolution of\ngross lesions were 14.5 and 20.75 days, respectively.\nIn all treated dogs, gross lesions resolved within\napproximately 21 days. Cats were treated once by\noral administration of lufenuron suspension in doses\nranging from 51.2 to 266 mg\/kg (23.3 to 120.9 mg\/lb).\nSamples were obtained daily from 23 cats; mean\ndurations from time of treatment to time of negative\nfungal culture results and resolution of gross lesions\nwere 8.3 and 12 days, respectively. Time to resolution\nof lesions in most untreated control animals was\napproximately 90 days. Adverse effects of treatment\nwere not detected.<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tConclusions and Clinical Relevance<\/jats:bold>\u2014Results of\nthis study suggest that lufenuron provides an effective,\nconvenient, and rapid method for treating fungal\ninfections in dogs and cats. (J Am Vet Med Assoc<\/jats:italic>\n2000;217:1510\u20131513)<\/jats:p>","DOI":"10.2460\/javma.2000.217.1510","type":"journal-article","created":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T17:44:46Z","timestamp":1133891086000},"page":"1510-1513","source":"Crossref","is-referenced-by-count":55,"title":["Use of lufenuron for treating fungal infections of dogs and cats: 297 cases (1997\u20131999)"],"prefix":"10.2460","volume":"217","author":[{"given":"Yair","family":"Ben-Ziony","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boaz","family":"Arzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"p_1_195","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1001\/archderm.1934.01460150003001","volume":"30","author":"Emmons CW","year":"1934","journal-title":"Arch Depart Syph"},{"key":"p_2_196","first-page":"698","volume":"695","author":"Jones TC","year":"1983","journal-title":"Philadelphia: Lea & Febiger"},{"key":"p_3_197","first-page":"295","author":"Muller GH","year":"1989","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_4_198","first-page":"1","volume":"18","author":"O'Neill CS","year":"1982","journal-title":"Carnation Res Dig"},{"key":"p_5_199","first-page":"1253","volume":"43","author":"Radenz WH","year":"1991","journal-title":"Am Fam Physician"},{"key":"p_6_200","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/j.1346-8138.1991.tb03098.x","volume":"18","author":"Katoh T","year":"1991","journal-title":"J Dermatol"},{"key":"p_7_201","unstructured":"Davis LE. Handbook of small animal therapeutics.New York: Churchill Livingstone Inc, 1985;619."},{"key":"p_8_202","unstructured":"Product info: PROGRAM, available at: http:\/\/www. novartis.ca\/product\/program.htm. Accessed May 15, 2000."},{"key":"p_9_203","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1365-3164.1995.tb00056.x","volume":"6","author":"Shipstone MA","year":"1995","journal-title":"Vet Dermatol"},{"key":"p_10_204","first-page":"484","author":"Bister SI","year":"1995","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_11_205","first-page":"14","author":"Jungerman FP","year":"1972","journal-title":"Philadelphia: Lea & Febiger"},{"key":"p_12_206","unstructured":"Hungerfold LL, Campbell CL, Smith AR. Veterinary mycology laboratory manual. Ames, Iowa: Iowa State University Press, 1998;44."}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/217\/10\/javma.2000.217.1510.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/217\/10\/javma.2000.217.1510.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/217\/10\/javma.2000.217.1510.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T14:08:15Z","timestamp":1741356495000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/217\/10\/javma.2000.217.1510.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11,15]]},"references-count":12,"journal-issue":{"issue":"10"},"URL":"https:\/\/doi.org\/10.2460\/javma.2000.217.1510","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2000,11,15]]}}}