{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T22:26:24Z","timestamp":1778279184398,"version":"3.51.4"},"reference-count":23,"publisher":"American Veterinary Medical Association (AVMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2000,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To determine long-term results and complications\nof gonadectomy performed at an early age\n(prepubertal) or at the traditional age in cats.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Cohort study.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u2014263 cats from animal shelters.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Cats that underwent gonadectomy were\nallotted to 2 groups on the basis of estimated age at\nsurgery (traditional age, \u2265 24 weeks old; prepubertal,\n&lt; 24 weeks old). Adoptive owner information was\nobtained from shelter records, and telephone interviews\nwere conducted with owners to determine\nphysical or behavioral problems observed in the cats\nafter adoption. Follow-up information was obtained\nfrom attending veterinarians for cats with complex\nproblems or when owners were uncertain regarding\nthe exact nature of their cat's problem.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014Compared with traditional-age gonadectomy,\nprepubertal gonadectomy did not result in an\nincreased incidence of infectious disease, behavioral\nproblems, or problems associated with any body system\nduring a median follow-up period of 37 months.\nAdditionally, the rate of retention in the original adoptive\nhousehold was the same for cats that underwent\nprepubertal gonadectomy as those that underwent\ntraditional-age gonadectomy.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Prepubertal\ngonadectomy may be performed safely in cats without\nconcern for increased incidence of physical or\nbehavioral problems for at least a 3-year period after\ngonadectomy. (<jats:italic>J Am Vet Med Assoc<\/jats:italic> 2000;217:\n1661\u20131665)<\/jats:p>","DOI":"10.2460\/javma.2000.217.1661","type":"journal-article","created":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T17:46:47Z","timestamp":1133891207000},"page":"1661-1665","source":"Crossref","is-referenced-by-count":56,"title":["Long-term outcome of gonadectomy performed at an early age or traditional age in cats"],"prefix":"10.2460","volume":"217","author":[{"given":"Lisa M.","family":"Howe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret R.","family":"Slater","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry W.","family":"Boothe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. 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