{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:09:31Z","timestamp":1788304171187,"version":"build-2803163510"},"reference-count":21,"publisher":"American Veterinary Medical Association (AVMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2001,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To evaluate the efficacy and safety of\nultrasonographically guided radiofrequency heat ablation\nof parathyroid masses in dogs with primary\nhyperparathyroidism.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Clinical trial.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201411 dogs.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014In all dogs, either 1 or 2 parathyroid\nmasses were evident ultrasonographically. Dogs\nwere anesthetized, and a 20-gauge over-the-needle\ncatheter was directed into the parathyroid mass via\nultrasonographic guidance. Radiofrequency heat\nwas applied to the stylet of the catheter until there\nwas sonographically apparent change to the entire\nparenchyma of the mass. Serum total and ionized\ncalcium and parathyroid hormone concentrations\nwere monitored daily for 5 days after the ablation\nprocedure and again at 1, 2, and 3-month intervals,\nif possible. Dogs were monitored for adverse\neffects.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014One treatment was required in 6 dogs, 2\ntreatments were required in 2 dogs, and treatment\nwas unsuccessful in 3 dogs. Serum total and ionized\ncalcium concentrations were within reference ranges\nwithin 2 days of the last procedure in all 8 successfully\ntreated dogs. Serum parathyroid hormone concentration\nwas decreased 24 hours after treatment in\nall 8 dogs. Hypocalcemia developed in 5 of the 8 successfully\ntreated dogs, all of which required treatment.\nOne dog had a transient voice change. Other\nadverse effects were not reported.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Ultrasonographically\nguided radiofrequency heat ablation of\nparathyroid masses is a safe and effective alternative\nto surgery in dogs with primary hyperparathyroidism.\n(<jats:italic>J Am Vet Med Assoc<\/jats:italic> 2001;218:1106\u20131110)<\/jats:p>","DOI":"10.2460\/javma.2001.218.1106","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T19:56:05Z","timestamp":1152302165000},"page":"1106-1110","source":"Crossref","is-referenced-by-count":59,"title":["Percutaneous ultrasonographically guided radiofrequency heat ablation for treatment of primary hyperparathyroidism in dogs"],"prefix":"10.2460","volume":"218","author":[{"given":"Rachel E.","family":"Pollard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig 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