{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:26:33Z","timestamp":1770218793436,"version":"3.49.0"},"reference-count":29,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2001,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To determine nonenteric sites associated\nwith <jats:italic>Escherichia coli<\/jats:italic> isolates in dogs and the antimicrobial\nsusceptibilities of the isolates.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Retrospective study.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Sample Population<\/jats:bold>\u201417,000 canine specimens.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Medical records of 17,000 canine specimens\nsubmitted for bacteriologic culture were examined\nand the number of isolations of <jats:italic>E coli<\/jats:italic> was determined.\nFor these cases, records were further examined\nwith respect to body system involvement, sex,\nconcurrent infection with other species of bacteria,\nand antimicrobial susceptibility.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014674 <jats:italic>E coli<\/jats:italic> isolates (424 from urine, 62 from\nthe skin, 52 from the respiratory tract, 45 from the\near, 43 from the female reproductive tract, 25 from\nthe male reproductive tract, and 23 from other organ\nsystems) were identified. There was a significantly\nhigher proportion of isolates from urine specimens\nfrom spayed females than from sexually intact\nfemales or males. <jats:italic>Escherichia coli<\/jats:italic> was isolated in\npure culture from 65.9% of the specimens. Most <jats:italic>E\ncoli<\/jats:italic> isolates were susceptible to norfloxacin (90%),\nenrofloxacin (87.5%), gentamicin (90.7%), and\namikacin (85.9%).<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Most nonenteric\n<jats:italic>E coli<\/jats:italic> infections in dogs involve the urinary tract.\nAmikacin, gentamicin, norfloxacin, and enrofloxacin\nhave the highest efficacy against canine <jats:italic>E coli<\/jats:italic> isolates.\nFor <jats:italic>E coli<\/jats:italic> isolates from dogs, in vitro susceptibility\nto commonly used antimicrobial agents has\nremained fairly stable during the past decade. (<jats:italic>J Am\nVet Med Assoc<\/jats:italic> 2001;218:381\u2013384)<\/jats:p>","DOI":"10.2460\/javma.2001.218.381","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T19:50:33Z","timestamp":1152301833000},"page":"381-384","source":"Crossref","is-referenced-by-count":30,"title":["Nonenteric Escherichia coli isolates from dogs: 674 cases (1990\u20131998)"],"prefix":"10.2460","volume":"218","author":[{"given":"Antony O.","family":"Oluoch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita M.","family":"Weisiger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun-Young","family":"Koo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur 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