{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T13:36:31Z","timestamp":1788183391718,"version":"build-2803163510"},"reference-count":15,"publisher":"American Veterinary Medical Association (AVMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2001,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To compare mean healing times after\ndebridement, debridement with grid keratotomy, and\nsuperficial keratectomy in cats with nonhealing\ncorneal ulcers.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Retrospective study.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201429 cats with 36 nonhealing corneal ulcers.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Medical records of cats with nonhealing\ncorneal ulcers were reviewed. Signalment, duration\nof clinical signs, ophthalmic abnormalities, and\nresponse to various treatment protocols were\nrecorded.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014Mean age of affected cats was 7 years, 8\nmonths. Affected breeds included domestic shorthair\n(17 cats), Persian (9), Himalayan (2), and Siamese (1).\nClinical signs were evident for approximately 2 weeks\nprior to referral. Both eyes were affected in 4 cats.\nMean healing time of ulcers treated with superficial\ndebridement was 30 days. Mean healing time of\nulcers treated with superficial debridement and grid\nkeratotomy was 42 days. Superficial keratectomy was\nperformed on 2 eyes and resulted in a healing time of\n2 weeks. Formation of a corneal sequestrum was evident\nin 2 of 21 eyes treated with superficial debridement.\nFormation of a corneal sequestrum was evident\nin 4 of 13 eyes treated with superficial debridement\nand grid keratotomy.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Brachycephalic\ncats appear to be predisposed to developing\nnonhealing corneal ulcers. The combination of superficial\ndebridement and grid keratotomy did not\ndecrease mean healing time of nonhealing ulcers,\ncompared with superficial debridement alone. Grid\nkeratotomy may predispose cats with corneal ulcers\nto develop a corneal sequestrum. (<jats:italic>J Am Vet Med\nAssoc<\/jats:italic> 2001;218:733\u2013735)<\/jats:p>","DOI":"10.2460\/javma.2001.218.733","type":"journal-article","created":{"date-parts":[[2006,1,23]],"date-time":"2006-01-23T18:38:38Z","timestamp":1138041518000},"page":"733-735","source":"Crossref","is-referenced-by-count":55,"title":["Nonhealing corneal ulcers in cats: 29 cases (1991\u20131999)"],"prefix":"10.2460","volume":"218","author":[{"given":"Noelle C. La","family":"Croix","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra van der","family":"Woerdt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis K.","family":"Olivero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"p_1_359","first-page":"38","volume":"4","author":"Morgan R","year":"1994","journal-title":"Vet Compend Ophthalmol"},{"key":"p_2_360","first-page":"84","volume":"25","author":"Kirschner S","year":"1989","journal-title":"J Am Anim Hosp Assoc"},{"key":"p_3_361","first-page":"31","volume":"3","author":"Peiffer R","year":"1976","journal-title":"Can Pract"},{"key":"p_4_362","first-page":"453","volume":"18","author":"Gelatt K","year":"1982","journal-title":"J Am Anim Hosp Assoc"},{"key":"p_5_363","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/S0195-5616(90)50054-6","volume":"20","author":"Kirschner S","year":"1990","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"p_6_364","first-page":"449","volume":"27","author":"Kirschner S","year":"1991","journal-title":"J Am Anim Hosp Assoc"},{"key":"p_7_365","first-page":"916","volume":"91","author":"Miller W","year":"1996","journal-title":"Vet Med"},{"key":"p_8_366","first-page":"885","volume":"20","author":"Morgan R","year":"1984","journal-title":"J Am Anim Hosp Assoc"},{"key":"p_9_367","first-page":"36","volume":"57","author":"Kuhns E","year":"1976","journal-title":"Mod Vet Prac"},{"key":"p_10_368","first-page":"347","volume":"80","author":"Chavkin M","year":"1990","journal-title":"Cornell Vet"},{"key":"p_11_369","first-page":"213","volume":"28","author":"Champagne E","year":"1992","journal-title":"J Am Anim Hosp Assoc"},{"key":"p_12_370","first-page":"561","volume":"90","author":"Pickett P","year":"1995","journal-title":"Vet Med"},{"key":"p_13_371","unstructured":"Startup F. Corneal ulceration. In: Wilkinson G, ed. Disease of the canine eye.New York: Pergamon Press, 1969;177."},{"key":"p_14_372","first-page":"1758","volume":"30","author":"Nasisse M","year":"1989","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"p_15_373","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/S0195-5616(84)50158-2","volume":"14","author":"Whitley R","year":"1984","journal-title":"Vet Clin North Am Small Anim Pract"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/218\/5\/javma.2001.218.733.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/218\/5\/javma.2001.218.733.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/218\/5\/javma.2001.218.733.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T14:00:52Z","timestamp":1741356052000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/218\/5\/javma.2001.218.733.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,3,1]]},"references-count":15,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.2460\/javma.2001.218.733","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2001,3,1]]}}}