{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:54:08Z","timestamp":1791395648030,"version":"4.3.3"},"reference-count":45,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2001,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To characterize skin lesions and causative\ninfections in diabetic dogs and evaluate other potential\ncauses of dermatologic disorders, including concurrent\nendocrinopathies, allergic skin disease, and\nlong-term corticosteroid administration.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Retrospective study.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201445 dogs with diabetes mellitus (DM) that\nwere examined by dermatologists.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Medical records were reviewed for signalment;\nallergic conditions prior to development of\nDM; prior corticosteroid administration; and results of\ndermatologic examinations, ear and skin cytologic\nexaminations, skin scrapings for parasites, bacteriologic\nand fungal culturing of ear and skin specimens,\nhistologic examinations, and endocrine testing.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014Bacterial skin infection was the most common\ndermatologic disorder (n = 38 [84%]), followed by\notitis (26 [58%]) and <jats:italic>Malassezia<\/jats:italic>-induced dermatitis\n(19 [42%]). Twenty-two (49%) dogs had pruritic skin\ndisease consistent with allergic dermatitis, which preceded\ndiagnosis of DM. Prior corticosteroid administration\nwas reported in 21 (47%) dogs. Concurrent\nhyperadrenocorticism was diagnosed in 13 (29%)\ndogs, and concurrent hypothyroidism was diagnosed\nin 5 (11%) dogs. Iatrogenic hyperadrenocorticism was\ndiagnosed in 1 additional dog. Only 10 (22%) dogs did\nnot have a documented concurrent endocrinopathy or\nallergic disease that could have caused the dermatitis.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Bacterial and\nyeast-induced dermatitis and otitis develop in dogs with\nDM. Many diabetic dogs with dermatologic problems\nhave a preexisting allergic condition, history of prior corticosteroid\nadministration, or concurrent endocrinopathy\nthat may be a more likely cause of dermatologic problems\nthan DM alone. (<jats:italic>J Am Vet Med Assoc<\/jats:italic> 2001:219:\n203\u2013208)<\/jats:p>","DOI":"10.2460\/javma.2001.219.203","type":"journal-article","created":{"date-parts":[[2006,1,23]],"date-time":"2006-01-23T18:36:29Z","timestamp":1138041389000},"page":"203-208","source":"Crossref","is-referenced-by-count":18,"title":["Dermatologic disorders in dogs with diabetes mellitus: 45 cases (1986\u20132000)"],"prefix":"10.2460","volume":"219","author":[{"given":"Heather","family":"Peikes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel O.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecka S.","family":"Hess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"p_1_93","first-page":"521","volume":"170","author":"Ling GV","year":"1977","journal-title":"J Am Vet Med Assoc"},{"key":"p_2_94","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0190-9622(94)70058-3","volume":"30","author":"Perez MI","year":"1994","journal-title":"J Am Acad Dermatol"},{"key":"p_3_95","doi-asserted-by":"crossref","first-page":"506","DOI":"10.2337\/diacare.21.4.506","volume":"21","author":"Yosipovitch G","year":"1998","journal-title":"Diabetes Care"},{"key":"p_4_96","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0195-5616(95)50065-8","volume":"25","author":"Diehl KJ","year":"1995","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"p_5_97","first-page":"965","author":"Parthaban S","year":"1995","journal-title":"Indian Vet J"},{"key":"p_6_98","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.217.1166"},{"key":"p_7_99","first-page":"548","volume":"72","author":"Wilkinson JS","year":"1960","journal-title":"Vet Rec"},{"key":"p_8_100","first-page":"339","author":"Feldman EC","year":"1996","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_9_101","first-page":"414","author":"Greene CE","year":"1998","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_10_102","first-page":"780","author":"Scott DW","year":"2001","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_11_103","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/S0195-5616(99)50131-9","volume":"29","author":"Byrne K","year":"1999","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"p_12_104","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1136\/vr.136.18.466","volume":"136","author":"Bond R","year":"1995","journal-title":"Vet Rec"},{"key":"p_13_105","first-page":"79","volume":"22","author":"Walton DK","year":"1986","journal-title":"J Am Anim Hosp Assoc"},{"key":"p_14_106","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1177\/030098589303000110","volume":"30","author":"Gross TL","year":"1993","journal-title":"Vet Pathol"},{"key":"p_15_107","first-page":"241","volume":"66","author":"Folz SD","year":"1985","journal-title":"Mod Vet Pract"},{"key":"p_16_108","first-page":"1209","volume":"172","author":"Chastain CB","year":"1978","journal-title":"J Am Vet Med Assoc"},{"key":"p_17_109","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S0195-5616(99)50128-9","volume":"29","author":"Morris DO","year":"1999","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"p_18_110","doi-asserted-by":"crossref","first-page":"334","DOI":"10.2460\/javma.1994.204.03.334","volume":"204","author":"Hill PB","year":"1994","journal-title":"J Am Vet Med Assoc"},{"key":"p_19_111","first-page":"574","author":"Muse R","year":"1999","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_20_112","first-page":"1538","author":"Feldman EC.","year":"1995","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_21_113","first-page":"1487","author":"Chastain CB","year":"1995","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_22_114","first-page":"187","author":"Feldman EC","year":"1996","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_23_115","first-page":"518","volume":"92","author":"Merchant SR","year":"1997","journal-title":"Vet Med"},{"key":"p_24_116","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.2460\/javma.1996.208.07.1048","volume":"208","author":"Kennis RA","year":"1996","journal-title":"J Am Vet Med Assoc"},{"key":"p_25_117","first-page":"25","author":"Reedy LM","year":"1997","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_26_118","first-page":"611","author":"DeBoer DJ","year":"1995","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_27_119","first-page":"1025","author":"Scott DW","year":"2001","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_28_120","first-page":"611","author":"Shanley KJ","year":"1995","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_29_121","first-page":"323","author":"Feldman EC","year":"1996","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_30_122","doi-asserted-by":"crossref","first-page":"126","DOI":"10.2460\/ajvr.1993.54.01.126","volume":"54","author":"Moore GE","year":"1993","journal-title":"Am J Vet Res"},{"key":"p_31_123","first-page":"954","author":"Kemppainen RJ","year":"1995","journal-title":"Philadelphia: WB Saunders Co"},{"key":"p_32_124","first-page":"685","volume":"191","author":"Zenoble RD","year":"1987","journal-title":"J Am Vet Med Assoc"},{"key":"p_33_125","doi-asserted-by":"crossref","first-page":"200","DOI":"10.5326\/15473317-35-3-200","volume":"35","author":"Huang H","year":"1999","journal-title":"J Am Anim Hosp Assoc"},{"key":"p_34_126","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/S0195-5616(88)50112-2","volume":"18","author":"Rosychuck RA.","year":"1988","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"p_35_127","first-page":"617","volume":"2","author":"Helton-Rhodes K","year":"1990","journal-title":"Prob Vet Med"},{"key":"p_36_128","first-page":"446","volume":"11","author":"White SD","year":"1989","journal-title":"Compend Contin Educ Pract Vet"},{"key":"p_37_129","first-page":"118","volume":"86","author":"Campbell KL","year":"1991","journal-title":"Vet Med"},{"key":"p_38_130","doi-asserted-by":"crossref","unstructured":"Scott DW. Hyperadrenocorticism (hyperadrenocorticoidism, hyperadrenocorticalism, cushing's disease, cushing's syndrome). Vet Clin North Am Small Anim Pract 1979;9:3-28.","DOI":"10.1016\/S0195-5616(79)50002-3"},{"key":"p_39_131","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0195-5616(79)50003-5","volume":"9","author":"Martin SL","year":"1979","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"p_40_132","doi-asserted-by":"crossref","first-page":"761","DOI":"10.2460\/javma.1994.204.05.761","volume":"204","author":"Panciera DL","year":"1994","journal-title":"J Am Vet Med Assoc"},{"key":"p_41_133","first-page":"287","volume":"20","author":"Rosychuck RA","year":"1998","journal-title":"Compend Contin Educ Pract Vet"},{"key":"p_42_134","doi-asserted-by":"crossref","first-page":"879","DOI":"10.2460\/javma.1992.201.06.879","volume":"201","author":"Plant JD","year":"1992","journal-title":"J Am Vet Med Assoc"},{"key":"p_43_135","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1996.tb01221.x"},{"key":"p_44_136","doi-asserted-by":"crossref","first-page":"616","DOI":"10.2460\/javma.1994.204.04.616","volume":"204","author":"Duclose DD","year":"1994","journal-title":"J Am Vet Med Assoc"},{"key":"p_45_137","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1365-3164.1996.tb00220.x","volume":"7","author":"Lemarie SL","year":"1996","journal-title":"Vet Dermatol"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/219\/2\/javma.2001.219.203.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/219\/2\/javma.2001.219.203.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/219\/2\/javma.2001.219.203.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:43:27Z","timestamp":1741355007000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/219\/2\/javma.2001.219.203.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7,15]]},"references-count":45,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.2460\/javma.2001.219.203","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2001,7,15]]}}}