{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T06:52:34Z","timestamp":1760079154600,"version":"3.38.0"},"reference-count":16,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2001,7,15]]},"abstract":"Abstract<\/jats:title>\n\t\t\t\t\n\t\t\t\t\tObjective<\/jats:bold>\u2014To determine the effects of estradiol cypionate\n(ECP) on measures of reproductive efficiency\nin postparturient dairy cows.<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tDesign<\/jats:bold>\u2014Randomized clinical trial.<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tAnimals<\/jats:bold>\u2014273 cows in a single herd in California.<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tProcedure<\/jats:bold>\u2014Twenty-four hours after parturition, 122\ncows were treated with ECP (4 mg, IM); the remaining\n151 cows were untreated controls. Percentages of cattle\nwith abnormal findings during uterine palpation 27\nto 40 days after parturition were compared between\ngroups, along with days to first artificial insemination\n(AI), percentages of cows that were not pregnant after\nthe first AI, and days to pregnancy.<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tResults<\/jats:bold>\u2014Treatment with ECP did not have a significant\neffect on whether results of uterine palpation 27\nto 40 days after parturition were abnormal, days to first\nAI, or odds that a cow would be pregnant after the first\nAI. Treatment with ECP appeared to have a negative\neffect on days to pregnancy (hazard ratio, 0.72)<\/jats:p>\n\t\t\t\t\n\t\t\t\t\tConclusions and Clinical Relevance<\/jats:bold>\u2014Results suggest\nthat prophylactic administration of ECP during the\nearly postparturient period in dairy cows did not have\nmeasurable beneficial effects on reproductive efficiency.\n(J Am Vet Med Assoc<\/jats:italic> 2001;219:220\u2013223)<\/jats:p>","DOI":"10.2460\/javma.2001.219.220","type":"journal-article","created":{"date-parts":[[2006,1,23]],"date-time":"2006-01-23T18:36:29Z","timestamp":1138041389000},"page":"220-223","source":"Crossref","is-referenced-by-count":8,"title":["Reproductive effects of estradiol cypionate in postparturient dairy cows"],"prefix":"10.2460","volume":"219","author":[{"given":"Denae C.","family":"Wagner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert H.","family":"BonDurant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M.","family":"Sischo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"p_1_177","unstructured":"Arrioja-Dechert A. 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