{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:53:46Z","timestamp":1791266026738,"version":"4.1.0"},"reference-count":45,"publisher":"American Veterinary Medical Association (AVMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2002,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To determine testing protocols used by\nboard-certified internists and dermatologists for diagnosis\nof hyperadrenocorticism (HAC) in dogs.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Survey.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Study Population<\/jats:bold>\u2014Board-certified internists and\ndermatologists.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014A questionnaire was mailed to 501 specialists\nto gather information pertaining to diagnosis\nof HAC.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014206 surveys were returned. Only 26% of\nrespondents indicated they would screen a dog for\nHAC if the dog had only a few laboratory abnormalities\nconsistent with HAC and no clinical signs consistent\nwith the disease; 31% indicated they would not, and\n43% indicated they would sometimes. Overall, 55% of\nrespondents indicated they preferred to use the lowdose\ndexamethasone suppression test for routine\nscreening of dogs suspected to have HAC. However,\nmany respondents indicated they would use a different\nscreening test than usual in particular circumstances.\nSixty-eight percent of respondents indicated they\nwould perform a second screening test for confirmation\nif results of an initial screening test were positive but\nthere were few clinical or laboratory abnormalities consistent\nwith HAC. Most respondents used some sort of\ntest to differentiate pituitary-dependent HAC from HAC\nsecondary to an adrenal tumor (AT), but no 1 test was\nclearly preferred. Ultrasonography was commonly\nused, whereas computed tomography and magnetic\nresonance imaging were not, even if available.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results suggest\nthat the low-dose dexamethasone suppression\ntest is the test most commonly used to screen dogs for\nHAC but that other tests may be used in certain circumstances.\nA variety of tests were used to differentiate\npituitary-dependent HAC from HAC secondary to an\nAT. 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