{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T17:39:55Z","timestamp":1770485995180,"version":"3.49.0"},"reference-count":43,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2002,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To determine whether serum concentrations\nof cardiac troponin I (cTnI) and cardiac troponin\nT (cTnT) are increased in dogs with gastric dilatationvolvulus\n(GDV) and whether concentrations correlate\nwith severity of ECG abnormalities or outcome.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Prospective case series.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201485 dogs with GDV.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Serum cTnI and cTnT concentrations\nwere measured 12 to 24, 48, 72, and 96 hours after\nsurgery. Dogs were grouped on the basis of severity\nof ECG abnormalities and outcome.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014cTnI and cTnT were detected in serum\nfrom 74 (87%) and 43 (51%) dogs, respectively.\nConcentrations were significantly different among\ngroups when dogs were grouped on the basis of\nseverity of ECG abnormalities (none or mild vs moderate\nvs severe). Dogs that died (n = 16) had significantly\nhigher serum cTnI (24.9 ng\/ml) and cTnT (0.18\nng\/ml) concentrations than did dogs that survived\n(2.05 and &lt; 0.01 ng\/ml, respectively). Myocardial cell\ninjury was confirmed at necropsy in 4 dogs with high\nserum cardiac troponin concentrations.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results indicate\nthat concentrations of cTnI and cTnT suggestive\nof myocardial cell injury can commonly be found in\nserum from dogs with GDV and that serum cardiac\ntroponin concentrations are associated with severity\nof ECG abnormalities and outcome. 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