{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:02:36Z","timestamp":1789038156195,"version":"build-2803163510"},"reference-count":24,"publisher":"American Veterinary Medical Association (AVMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2003,10,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To determine signalment, history, clinical\nsigns, blood and plasma taurine concentrations, electrocardiographic\nand echocardiographic findings,\ntreatment, and outcome of dogs with low blood or\nplasma taurine concentrations and dilated cardiomyopathy\n(DCM).<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Retrospective study.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201412 client-owned dogs with low blood or\nplasma taurine concentrations and DCM.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Medical records were reviewed, and\nclinical data were obtained.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014All 12 dogs were being fed a commercial\ndry diet containing lamb meal, rice, or both as primary\ningredients. Cardiac function and plasma taurine\nconcentration improved with treatment and taurine\nsupplementation. Seven of the 12 dogs that were still\nalive at the time of the study were receiving no cardiac\nmedications except taurine.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results suggest\nthat consumption of certain commercial diets may\nbe associated with low blood or plasma taurine concentrations\nand DCM in dogs. Taurine supplementation\nmay result in prolonged survival times in these dogs,\nwhich is not typical for dogs with DCM. Samples should\nbe submitted for measurement of blood and plasma\ntaurine concentrations in dogs with DCM, and taurine\nsupplementation is recommended while results of\nthese analyses are pending. 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