{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T08:18:13Z","timestamp":1768724293324,"version":"3.49.0"},"reference-count":26,"publisher":"American Veterinary Medical Association (AVMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2003,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To determine efficacy and safety of percutaneous\nradiofrequency heat ablation for treatment\nof hyperthyroidism in cats.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Prospective study.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u20149 cats.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Hyperthyroidism was diagnosed via clinical\nsigns and high serum total (TT<jats:sub>4<\/jats:sub>) and free thyroxine\n(fT<jats:sub>4<\/jats:sub>) concentrations. One or 2 hyperfunctional cervical\nthyroid nodules were detected by use of scintigraphy\nand ultrasonography. If cats had 1 abnormal thyroid\nlobe, heat ablation was performed on that lobe; if\ncats had 2 abnormal lobes, heat ablation was applied\nto the larger lobe. Overall, heat ablation was performed\n14 times in the 9 cats. Clinical signs and\nserum TT<jats:sub>4<\/jats:sub>, fT<jats:sub>4<\/jats:sub>, and calcium concentrations were\nmonitored daily for 2 days after the procedure, weekly\nfor the first month, and then monthly. Laryngeal\nfunction was evaluated and cervical ultrasonography\nand thyroid scintigraphy were also performed.\nMonitoring continued for as long as 9 months after\nheat ablation if a cat became euthyroid or until an\nowner chose an alternative treatment because of\nrecurrence of hyperthyroidism.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014Serum TT<jats:sub>4<\/jats:sub> and fT<jats:sub>4<\/jats:sub> concentrations transiently\ndecreased after all 14 heat ablation procedures (\u2264\nreference range after 10 of 14 treatments) within 2\ndays after the procedure. Cats were euthyroid for 0 to\n18 months (mean, 4 months). Hyperthyroidism\nrecurred in all cats. Adverse effects included transient\nHorner's syndrome (2 cats) and laryngeal paralysis\nwithout clinical signs (1 cat).<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Percutaneous\nheat ablation as a treatment for hyperthyroidism in cats\nis effective transiently but not permanently. (<jats:italic>J Am Vet\nMed Assoc<\/jats:italic> 2003;223:1602\u20131607)<\/jats:p>","DOI":"10.2460\/javma.2003.223.1602","type":"journal-article","created":{"date-parts":[[2005,12,22]],"date-time":"2005-12-22T13:05:23Z","timestamp":1135256723000},"page":"1602-1607","source":"Crossref","is-referenced-by-count":40,"title":["Percutaneous ultrasound-guided radiofrequency heat ablation for treatment of hyperthyroidism in cats"],"prefix":"10.2460","volume":"223","author":[{"given":"Kevin F.","family":"Mallery","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel E.","family":"Pollard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard W.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William 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