{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T20:40:10Z","timestamp":1793392810102,"version":"4.5.0"},"reference-count":18,"publisher":"American Veterinary Medical Association (AVMA)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2004,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To determine clinical signs and rhinoscopic,\ncomputed tomographic, and histologic abnormalities\nin dogs with idiopathic lymphoplasmacytic rhinitis.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201437 dogs.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Clinical information was obtained from\nmedical records. Nasal computed tomographic\nimages and histologic slides of biopsy specimens\nwere reviewed.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u2014Dogs ranged from 1.5 to 14 years old\n(mean, 8 years); most (28) were large-breed dogs.\nNasal discharge was unilateral in 11 of 26 (42%)\ndogs and bilateral in 15 of 26 (58%) dogs. In dogs\nwith unilateral disease, duration of clinical signs\nranged from 1.5 to 36 months (mean, 8.25 months;\nmedian, 2 months), and in dogs with bilateral disease,\nduration of signs ranged from 1.25 to 30\nmonths (mean, 6.5 months; median, 4 months).\nComputed tomography (n = 33) most often revealed\nfluid accumulation (27\/33 [82%]), turbinate destruction\n(23\/33 [70%]), and frontal sinus opacification\n(14\/33 [42%]). Rhinoscopy (n = 37) commonly\ndemonstrated increased mucus and epithelial\ninflammation; turbinate destruction was detected in\n8 of 37 (22%) dogs. Bilateral biopsy specimens from\nall 37 dogs were examined. Four dogs had only unilateral\ninflammatory changes. The remaining 33 dogs\nhad bilateral lesions; in 20, lesions were more\nsevere on 1 side than the other.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Findings suggest\nthat idiopathic lymphoplasmacytic rhinitis is a key\ncontributor to chronic nasal disease in dogs and may be\nmore common than previously believed. In addition, findings\nsuggest that idiopathic lymphoplasmacytic rhinitis is\nmost often a bilateral disease, even among dogs with\nunilateral nasal discharge. 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