{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T04:14:29Z","timestamp":1785212069969,"version":"3.55.0"},"reference-count":29,"publisher":"American Veterinary Medical Association (AVMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2005,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Objective<\/jats:bold>\u2014To determine factors associated with\nlong-term survival in dogs treated surgically for patent\nductus arteriosus (PDA).<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Animals<\/jats:bold>\u201452 dogs treated surgically for left-to-right\nshunting PDA.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Procedure<\/jats:bold>\u2014Data pertaining to age, breed, sex, body\nweight, clinical examination findings, type and duration\nof medical treatment, results of thoracic radiography\nand echocardiography, and surgical and postoperative\ncomplications were collected from records.\nFollow-up information was obtained from medical\nrecords or telephone interviews with owners or referring\nveterinarians.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Results<\/jats:bold>\u201422 dogs had mitral valve regurgitation.\nMean weight and age were not significantly different\nbetween dogs with or without mitral valve regurgitation.\nTwenty-four (46.2%) dogs had clinical signs related\nto cardiac insufficiency. Left atrial dilatation was\nobserved in 56.3% of dogs that were radiographed.\nSonographic imaging was used to diagnose left atrial\ndilatation in 23 dogs and left ventricular dilatation in\n25 dogs. The 1- and 2-year survival rates were 92%\nand 87%, respectively. Diagnosis of mitral valve\nregurgitation before surgery was not associated with\nthe probability of survival. Age, weight, lethargy, preoperative\ntreatment with angiotensin-converting\nenzyme inhibitors, and right atrial dilatation on radiographs\nat the time of surgery were negatively associated\nwith probability of survival.<\/jats:p>\n\t\t\t\t<jats:p>\n\t\t\t\t\t<jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Surgical treatment\nof PDA was curative in young dogs without clinical\nsigns of heart failure. Surgical correction of PDA should\nbe recommended as early as possible after diagnosis,\nand mitral valve regurgitation is not a contraindication for\nsurgery. 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