{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T18:24:34Z","timestamp":1793471074782,"version":"4.5.0"},"reference-count":54,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2005,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective<\/jats:bold>\n                    \u2014To determine signalment, clinical features\nof the disease, and treatment in dogs with\ndiskospondylitis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design<\/jats:bold>\n                    \u2014Case-control study.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Animals<\/jats:bold>\n                    \u2014513 dogs with diskospondylitis (cases) and\n236,109 canine hospital accessions (controls) from 12\nveterinary teaching hospitals.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Procedure<\/jats:bold>\n                    \u2014Information retrieved from the medical\nrecords of 123 dogs with diskospondylitis at the\nLouisiana State University veterinary teaching hospital\nbetween 1980 and 2001 included sex, age, breed,\nprimary complaint, neurologic status, location of\nlesions, causative organism, treatment, and outcome.\nThe signalment of 390 additional cases from 11 other\nveterinary teaching hospitals was accessed from the\nVeterinary Medical Database. Comparisons were\nmade with controls from the same time periods.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    \u2014Male dogs were twice as likely as female\ndogs to be affected (odds ratio [OR], 2.0; 95% confidence\ninterval [CI], 1.7 to 2.4). Dogs were significantly\nmore likely to be affected as age increased. Purebred\ndogs, especially Great Danes, were more likely than\nmixed-breed dogs to be affected (OR, 7.3; CI, 4.3\nto 12.6). For dogs from Louisiana State University,\n                    <jats:italic>Staphylococcus<\/jats:italic>\n                    spp,\n                    <jats:italic>Brucella<\/jats:italic>\n                    spp,\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    spp,\nand\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    were isolated most often; multiple\norganisms were detected via microbial culture in 11\ndogs. The mean duration of treatment was 53.7 weeks.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\n                    \u2014Male dogs,\nolder dogs, and Great Danes appeared more likely to\nbe affected with diskospondylitis than female dogs,\ndogs &lt; 1 year of age, and mixed-breed dogs, respectively.\nLong-term administration of antimicrobial drugs\nfor treatment of diskospondylitis may be expected.\nIdentification of the causative organism and early\ntreatment are recommended. 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