{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:40:29Z","timestamp":1785498029898,"version":"3.56.0"},"reference-count":31,"publisher":"American Veterinary Medical Association (AVMA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2022,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To document ocular findings in cats with blastomycosis.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>ANIMALS<\/jats:title>\n<jats:p>35 cats with blastomycosis.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>PROCEDURES<\/jats:title>\n<jats:p>Medical records from 1978 through 2019 were reviewed to identify cats with confirmed <jats:italic>Blastomyces<\/jats:italic> infection. Cats were grouped as having or not having ocular involvement. Clinical signs, histopathologic findings, and response to treatment were evaluated.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>21 of the 35 (60%) cats with confirmed blastomycosis had ocular abnormalities. Two of 21 cats with ocular abnormalities also had systemic hypertension and were excluded. Of the remaining 19 cats, 15 (79%) had bilateral ocular signs. Ten (53%) cats had inflammatory ocular lesions, and 9 (47%) had neuro-ophthalmic abnormalities. Six of the 19 (32%) cats appeared to be completely blind, and 5 (26%) appeared to be unilaterally blind. For the 10 cats with inflammatory ocular lesions, the most common lesions were anterior uveitis (9\/20 eyes), active chorioretinitis (6\/20 eyes), and retinal detachment (4\/20 eyes). For the 9 cats with neuro-ophthalmic abnormalities, the most common abnormalities were a negative menace or tracking response (10\/18 eyes) and negative pupillary light response (4\/18 eyes).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>Results suggested that ocular involvement is common in cats with blastomycosis and that both inflammatory lesions and neuro-ophthalmic abnormalities can be seen. Blastomycosis should be considered in the differential diagnosis for cats with anterior uveitis, posterior segment inflammation, or neuro-ophthalmic abnormalities, and a complete ophthalmic examination should be performed in all cats with confirmed or suspected blastomycosis.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.21.03.0135","type":"journal-article","created":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T16:29:28Z","timestamp":1640104168000},"page":"422-427","source":"Crossref","is-referenced-by-count":5,"title":["Ocular findings in cats with blastomycosis: 19 cases (1978\u20132019)"],"prefix":"10.2460","volume":"260","author":[{"given":"Jacob M.","family":"Morris","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex B.","family":"Sigmund","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel A.","family":"Ward","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane V. H.","family":"Hendrix","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Infectious Diseases of the Dog and Cat","first-page":"606","article-title":"Blastomycosis","author":"Legendre AM","year":"2012","unstructured":"Legendre AM. Blastomycosis. In: Greene CE, ed. Infectious Diseases of the Dog and Cat. 4th ed. Elsevier\/Saunders; 2012:606\u2013613."},{"key":"ref2","series-title":"Emerging and Epizootic Fungal Infections in Animals","first-page":"159","article-title":"Blastomycosis in mammals","author":"Schwartz IS","year":"2018","unstructured":"Schwartz IS. Blastomycosis in mammals. In: Seyedemousavi S, de Hoog G, Guillot J, Verweij P, eds. Emerging and Epizootic Fungal Infections in Animals. 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