{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T10:48:44Z","timestamp":1764240524246,"version":"3.38.0"},"reference-count":29,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2022,3,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>CASE DESCRIPTION<\/jats:title>\n<jats:p>A 9-year-old spayed female Maine Coon cat was presented at the University of Veterinary Medicine Vienna for further investigation of chronic nonpruritic bilateral ear disease and unilateral Horner syndrome.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL FINDINGS<\/jats:title>\n<jats:p>Physical examination and otoscopy findings included right sided Horner syndrome, a right head tilt of approximately 20\u00b0 and a small pink nodule in the right and several smaller nodules in the left proximal horizontal external ear canal. Computed tomography and magnetic resonance imaging revealed soft tissue opacity material in both middle ear cavities, the caudal portion of the nasal cavity, the left nasopharyngeal meatus and the right frontal sinus. Via videootoscopy, 2 multilobular and several flat nodules were detected in the proximal right horizontal external ear canal and in the left tympanic bulla, respectively. Histopathological examination confirmed the diagnosis of cholesterol granulomas.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>TREATMENT AND OUTCOME<\/jats:title>\n<jats:p>All otic cholesterol granulomas (CGs) were removed via video-otoscopy (VO), and topical treatment was initiated in addition to oral prednisolone. After the histopathological confirmation, negative microbial cultures from the middle ear cavities, and the remission of the symptoms by the first recheck, topical, and systemic treatment were discontinued. A follow-up 6 months later, did not reveal any recurrence of the CGs.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>To our knowledge, this is the first case of bilateral CGs diagnosed with a combination of CT, MRI, VO, and histopathology and removed minimal invasively via VO, without a need for ventral bulla osteotomy, which led to complete remission of all signs and no relapse until the follow up 6 months later.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.21.03.0149","type":"journal-article","created":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T14:40:45Z","timestamp":1646836845000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["Bilateral cholesterol granulomas in the middle ear cavities of a cat with sinonasal disease successfully removed via video-otoscopy"],"prefix":"10.2460","volume":"260","author":[{"given":"Pavlos G.","family":"Doulidis","sequence":"first","affiliation":[{"name":"Department for Companion Animals and Horses, Clinical Unit of Small Animals Internal Medicine, Dermatology, University of Veterinary Medicine, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Klang","sequence":"additional","affiliation":[{"name":"Institute of Pathology, Department for Pathobiology, University of Veterinary Medicine, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michaela","family":"Gumpenberger","sequence":"additional","affiliation":[{"name":"Department for Companion Animals and Horses, Diagnostic Imaging, University of Veterinary Medicine, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Panakova","sequence":"additional","affiliation":[{"name":"Department for Companion Animals and Horses, Clinical Unit of Small Animals Internal Medicine, Dermatology, University of Veterinary Medicine, Vienna, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"issue":"6","key":"ref1","series-title":"Laryngoscope","first-page":"659","article-title":"Cholesterol granuloma of the petrous apex","volume":"95","author":"Gherini SG","year":"1985","unstructured":"Gherini SG, Brackmann DE, Lo WW, Solti-Bohman LG. 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