{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T01:43:50Z","timestamp":1789695830324,"version":"4.0.1"},"reference-count":48,"publisher":"American Veterinary Medical Association (AVMA)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To determine changes in health-related quality of life up to 12 months after surgery in dogs with myxomatous mitral valve disease that undergo mitral valve repair.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>ANIMALS<\/jats:title>\n<jats:p>54 dogs that underwent mitral valve repair at a United Kingdom referral hospital.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>PROCEDURES<\/jats:title>\n<jats:p>Health-related quality of life was assessed with a previously validated, owner-completed questionnaire before and 1, 3, 6, and 12 months after surgery.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>There was a significant decrease in total score (corresponding to reduced negative impact of cardiac disease on quality of life) between the preoperative timepoint and all postoperative timepoints. A significant decrease in total score was also demonstrated between the 1- and 3-month timepoints, but no additional significant changes in total score between adjacent timepoints were identified beyond 3 months after surgery. Significant improvements in individual question scores were found up to 12 months after surgery.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>Health-related quality of life was significantly improved following mitral valve repair in dogs with myxomatous mitral valve disease and this improvement persisted for up to a year after surgery. These results may be useful when counseling owners of dogs considered candidates for this procedure.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.22.02.0053","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T16:02:21Z","timestamp":1653062541000},"page":"1806-1812","source":"Crossref","is-referenced-by-count":11,"title":["Use of the Functional Evaluation of Cardiac Health questionnaire to assess health-related quality of life before and after mitral valve repair in dogs with myxomatous mitral valve disease"],"prefix":"10.2460","volume":"260","author":[{"given":"Catrina","family":"Pennington","sequence":"first","affiliation":[{"name":"Small Animal Teaching Hospital, School of Veterinary Science, University of Liverpool, Wirral, UK"},{"name":"Queen Mother Hospital for Animals, Royal Veterinary College, Hertfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsumugi Anne","family":"Kurosawa","sequence":"additional","affiliation":[{"name":"Dick White Referrals Ltd, Cambridgeshire, UK"},{"name":"Queen Mother Hospital for Animals, Royal Veterinary College, Hertfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Navarro-Cubas","sequence":"additional","affiliation":[{"name":"Southfields Veterinary Specialists, Laindon, UK"},{"name":"Queen Mother Hospital for Animals, Royal Veterinary College, Hertfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poppy","family":"Bristow","sequence":"additional","affiliation":[{"name":"Dick White Referrals Ltd, Cambridgeshire, UK"},{"name":"Queen Mother Hospital for Animals, Royal Veterinary College, Hertfordshire, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"3","key":"ref1","series-title":"J Vet Intern Med","first-page":"847","article-title":"Prevalence of and risk factors for degenerative mitral valve disease in dogs attending primary-care veterinary practices in England","volume":"29","author":"Mattin MJ","year":"2015","unstructured":"Mattin MJ, Boswood A, Church DB,  Prevalence of and risk factors for degenerative mitral valve disease in dogs attending primary-care veterinary practices in England. 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