{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:40:29Z","timestamp":1785498029664,"version":"3.56.0"},"reference-count":15,"publisher":"American Veterinary Medical Association (AVMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2022,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To describe the prevalence of ocular lesions in cats with newly diagnosed histoplasmosis.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>ANIMALS<\/jats:title>\n<jats:p>55 client-owned domestic cats.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>PROCEDURES<\/jats:title>\n<jats:p>As part of this prospective case series, cats diagnosed with histoplasmosis between the years 2015 and 2020 underwent complete ophthalmic examinations by a board-certified veterinary ophthalmologist prior to the initiation of antifungal treatment. Histoplasmosis was diagnosed by consistent clinical findings and identification of <jats:italic>Histoplasma<\/jats:italic> yeast on pathology or by the use of a commercially available enzyme immunoassay to detect <jats:italic>Histoplasma<\/jats:italic> antigen in urine.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Of the 55 cats, 45 (82%; 95% CI, 72% to 92%) had signs of active anterior, posterior, or panuveitis. The most common lesions were identified in the posterior portion of the globe and included chorioretinitis and partial retinal detachments (44\/55 [80%; 95% CI, 69% to 90%] cats).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>Detailed ophthalmic examinations should be performed on all cats with diagnosed or suspected histoplasmosis, as ocular involvement and subsequent vision loss are common.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.22.03.0142","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T16:02:10Z","timestamp":1653062530000},"page":"1330-1333","source":"Crossref","is-referenced-by-count":4,"title":["Prevalence of ocular lesions in cats newly diagnosed with histoplasmosis: 55 cases (2015\u20132022)"],"prefix":"10.2460","volume":"260","author":[{"given":"Jonathan D.","family":"Pucket","sequence":"first","affiliation":[{"name":"Oklahoma Veterinary Specialists, Tulsa, OK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katelyn E.","family":"Fentiman","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily S.","family":"McCool","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew S.","family":"Hanzlicek","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"5","key":"ref1","series-title":"J Am Anim Hosp Assoc","first-page":"380","article-title":"Deep mycotic infections in cats","volume":"32","author":"Davies C","year":"1996","unstructured":"Davies C, Troy GC. Deep mycotic infections in cats. J Am Anim Hosp Assoc. 1996;32(5):380\u2013391. doi:10.5326\/15473317-32-5-3808875352"},{"issue":"4","key":"ref2","series-title":"Clin Tech Small Anim Pract","first-page":"227","article-title":"Histoplasmosis in dogs and cats","volume":"20","author":"Br\u00f6mel C","year":"2005","unstructured":"Br\u00f6mel C, Sykes JE. Histoplasmosis in dogs and cats. Clin Tech Small Anim Pract. 2005;20(4):227\u2013232. doi:10.1053\/j.ctsap.2005.07.00316317912"},{"key":"ref3","series-title":"Infectious Diseases of the Dog and Cat","first-page":"614","author":"Br\u00f6mel C","year":"2012","unstructured":"Br\u00f6mel C, Greene CE. In: Infectious Diseases of the Dog and Cat. 4th ed. Elsevier\/Saunders; 2012:614\u2013621."},{"key":"ref4","series-title":"Emerging and Epizootic Fungal Infections in Animals","first-page":"115","article-title":"Histoplasmosis in animals","author":"Guillot J","year":"2018","unstructured":"Guillot J, Guerin C, Chermette R. 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Clin Vaccine Immunol. 2007;14(12):1587\u20131591. doi:10.1128\/CVI.00071-0717913863"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/260\/11\/javma.22.03.0142.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/260\/11\/javma.22.03.0142.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/260\/11\/javma.22.03.0142.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T15:20:18Z","timestamp":1727450418000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/260\/11\/javma.22.03.0142.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,1]]},"references-count":15,"journal-issue":{"issue":"11"},"URL":"https:\/\/doi.org\/10.2460\/javma.22.03.0142","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8,1]]}}}