{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T04:36:31Z","timestamp":1771648591776,"version":"3.50.1"},"reference-count":10,"publisher":"American Veterinary Medical Association (AVMA)","issue":"S1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2023,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>Skin diseases are one of the most common problems seen in veterinary practices around the world. Many patients are presented with severe and\/or chronic lesions, often refractory to treatment, and collection of skin biopsies is often beneficial to obtain or confirm a diagnosis and to help guide a management plan for patients. To obtain valuable information from skin biopsies, practitioners should follow recommended guidelines based on drug withdrawal and washout period, identification, and proper collection of skin lesions, which should be at different stages of progression, as well as include a thorough clinical history and differential list. These different steps taken prior to the submission of samples will often increase the chances of a more accurate diagnosis. Practitioners should also understand it may not always be possible for pathologists to provide a definitive diagnosis, but the information provided with skin biopsies can often be used to guide an appropriate treatment plan. This review will present general guidelines and suggestions to help obtain the most diagnostic skin samples for histopathological evaluation.<\/jats:p>","DOI":"10.2460\/javma.22.12.0586","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T12:22:16Z","timestamp":1681129336000},"page":"S114-S121","source":"Crossref","is-referenced-by-count":3,"title":["Skin biopsy guidelines: tips and advice from veterinary pathologists to practitioners"],"prefix":"10.2460","volume":"261","author":[{"given":"William F.","family":"Craft","sequence":"first","affiliation":[{"name":"Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosanna","family":"Marsella","sequence":"additional","affiliation":[{"name":"Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline","family":"Rodrigues-Hoffmann","sequence":"additional","affiliation":[{"name":"Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"B1","series-title":"Muller and Kirk\u2019s Small Animal Dermatology","first-page":"57","article-title":"Diagnostic methods","author":"Miller WH","year":"2013","unstructured":"Miller WH, Griffin CE, Campbell KL. Diagnostic methods. In: Miller WH, Griffin CE, Campbell KL, eds. Muller and Kirk\u2019s Small Animal Dermatology. 7th ed. Elsevier Mosby; 2013:57\u2013107."},{"key":"B2","series-title":"Practical Veterinary Dermatopathology","first-page":"1","article-title":"Biopsy collection: why, when, where and how","author":"Bettenay SV","year":"2006","unstructured":"Bettenay SV, Hargis AM. Biopsy collection: why, when, where and how. In: Practical Veterinary Dermatopathology. Teton NewMedia; 2006:1\u201320."},{"key":"B3","series-title":"Small Animal Dermatology: a Colour Atlas and Therapeutic GuideI","first-page":"30","article-title":"Diagnostic techniques","author":"Hnilica K","year":"2016","unstructured":"Hnilica K, Patterson A. Diagnostic techniques. In: Small Animal Dermatology: a Colour Atlas and Therapeutic GuideI. 4th ed. Elsevier Saunders; 2016:30\u201344."},{"key":"B4","series-title":"Diagnostics and Therapy in Veterinary Dermatology","first-page":"33","article-title":"When, where, and how to biopsy skin","author":"Logas D","year":"2022","unstructured":"Logas D. When, where, and how to biopsy skin. In: Diagnostics and Therapy in Veterinary Dermatology. Wiley Blackwell; 2022:33\u201338."},{"issue":"3","key":"B5","series-title":"Vet Dermatol","first-page":"266-e38","article-title":"Diagnosis and treatment of dermatophytosis in dogs and cats","volume":"28","author":"Moriello KA","year":"2017","unstructured":"Moriello KA, Coyner K, Paterson S, Mignon B. Diagnosis and treatment of dermatophytosis in dogs and cats. Vet Dermatol. 2017;28(3):266-e38. doi:10.1111\/vde.12440"},{"key":"B6","series-title":"Small Animal Dermatology Secrets","first-page":"34","article-title":"A guide to taking skin biopsies: a pathologist\u2019s perspective","author":"Dunstan RW","year":"2004","unstructured":"Dunstan RW, Mauldin EA, Davenport GM, Credille KM. A guide to taking skin biopsies: a pathologist\u2019s perspective. In: Campbell KL, ed. Small Animal Dermatology Secrets. Hanley and Belfus; 2004:34\u201342."},{"key":"B7","series-title":"Skin Diseases of the Dog and Cat Clinical and Histopathologic Diagnosis","author":"Gross TL","year":"2005","unstructured":"Gross TL, Ihrke PJ, Walder EJ, Affolter VK. Skin Diseases of the Dog and Cat Clinical and Histopathologic Diagnosis. 2nd ed. Blackwell Science; 2005."},{"key":"B8","series-title":"Pathologic Basis of Veterinary Disease","first-page":"1095","article-title":"The integument","author":"Welle M","year":"2022","unstructured":"Welle M, Linder K. The integument. In: Zachary JW, ed. Pathologic Basis of Veterinary Disease. 7th ed. Elsevier; 2022:1095\u20131262."},{"key":"B9","article-title":"Biopsying places you don\u2019t want to biopsy: footpads, claws, ears, and noses","author":"Fadok V","unstructured":"Fadok V. Biopsying places you don\u2019t want to biopsy: footpads, claws, ears, and noses. Veterinary Information Network (VIN). Accessed December 23, 2022. http:\/\/www.vin.com\/Members\/Proceedings\/Proceedings.plx?CID=MEDFAQ&Category=1477&PID=52461&O=VIN"},{"key":"B10","series-title":"Jubb, Kennedy & Palmer\u2019s Pathology of Domestic Animals","first-page":"509","article-title":"Integumentary system","volume":"Vol 1","author":"Mauldin EA","year":"2016","unstructured":"Mauldin EA, Peters-Kennedy J. Integumentary system. In: Maxie MG, ed. Jubb, Kennedy & Palmer\u2019s Pathology of Domestic Animals. Vol 1. Elsevier; 2016:509\u2013736.e1."}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/261\/S1\/javma.22.12.0586.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/261\/S1\/javma.22.12.0586.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/261\/S1\/javma.22.12.0586.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T12:57:09Z","timestamp":1741352229000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/261\/S1\/javma.22.12.0586.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,1]]},"references-count":10,"journal-issue":{"issue":"S1"},"URL":"https:\/\/doi.org\/10.2460\/javma.22.12.0586","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6,1]]}}}