{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:36:31Z","timestamp":1787841391156,"version":"build-2784847793"},"reference-count":18,"publisher":"American Veterinary Medical Association (AVMA)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2006,3,15]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:bold>\n \u2014To further classify dysmyelopoiesis as diagnosed by use of a general classification scheme and to determine clinical features and laboratory test results that could be used to differentiate between the various forms of dysmyelopoiesis in cats.\n <\/jats:p>\n \n Design<\/jats:bold>\n \u2014Retrospective case series.\n <\/jats:p>\n \n Sample Population<\/jats:bold>\n \u2014Bone marrow slides from 34 cats.\n <\/jats:p>\n \n Procedures<\/jats:bold>\n \u2014Medical records of cats in which dysmyelopoiesis was diagnosed on the basis of blood and bone marrow analyses from 1996 to 2005 were reviewed. Criteria for inclusion in the study were findings of > 10% dysplastic cells in 1 or more hematologic cell lines in the bone marrow and concurrent cytopenias in the blood. Cats that met these criteria were classified into subcategories of myelodysplastic syndromes or secondary dysmyelopoiesis on the basis of reevaluation of slides.\n <\/jats:p>\n \n Results<\/jats:bold>\n \u2014Of 189 bone marrow slides reviewed, 34 (14.9%) had > 10% dysplastic cells in 1 or more cell lines. Cats were subcategorized as having myelodys-plastic syndrome with excessive numbers of blast cells (n = 13), myelodysplastic syndrome with refractory cytopenias (8), a variant form of myelodysplastic syndrome (1), and secondary dysmyelopoiesis (12). Findings of dysmyelopoiesis and autoagglutination in cats with myelodysplastic syndrome and in those with immune-mediated anemia complicated differentiating between the 2 conditions.\n <\/jats:p>\n \n Conclusions and Clinical Relevance<\/jats:bold>\n \u2014Differentiating cats with myelodysplastic syndromes from cats with immune-mediated hemolytic anemia was difficult because severe anemia and autoagglutination may be concurrent findings in both conditions. Differentiating between myelodysplastic syndrome with excessive numbers of blast cells and myelodysplastic syndrome with refractory cytopenias was useful in predicting clinical outcome.\n <\/jats:p>","DOI":"10.2460\/javma.228.6.893","type":"journal-article","created":{"date-parts":[[2006,3,14]],"date-time":"2006-03-14T17:09:27Z","timestamp":1142356167000},"page":"893-897","source":"Crossref","is-referenced-by-count":24,"title":["Evaluation of dysmyelopoiesis in cats: 34 cases (1996\u20132005)"],"prefix":"10.2460","volume":"228","author":[{"given":"Douglas J.","family":"Weiss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Vet Intern Med","first-page":"147","article-title":"Recognition and classification of dysmyelopoiesis in the dog: a review","volume":"19","author":"Weiss","year":"2005"},{"key":"ref2","series-title":"Vet Clin Pathol","first-page":"67","article-title":"Cytologic evaluation of primary and secondary myelodysplastic syndromes in the dog","volume":"30","author":"Weiss","year":"2001"},{"key":"ref3","series-title":"Schalm's veterinary hematology","first-page":"682","article-title":"Myelodysplastic syndromes and myelofibrosis","author":"Blue","year":"2000"},{"key":"ref4","series-title":"Br J Haematol","first-page":"189","article-title":"Proposals for the classification of the acute leukemias","volume":"51","author":"Bennett","year":"1982"},{"key":"ref5","series-title":"Comp Haematol Int","first-page":"125","article-title":"Classification of myeloproliferative disorders in cats using the criteria proposed by the animal leukemia study group: a retrospective study of 181 cases (1969\u20131992)","volume":"3","author":"Jain","year":"1993"},{"key":"ref6","series-title":"Vet Clin North Am Small Anim Pract","first-page":"1023","article-title":"Myelopoiesis and myeloproliferative 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J","first-page":"459","article-title":"The blood and marrow picture of the cat","volume":"126","author":"Penny","year":"1970"},{"key":"ref17","series-title":"J Am Vet Med Assoc","first-page":"75","article-title":"Pure red cell aplasia in cats: 9 cases (1989\u20131997)","volume":"214","author":"Stokol","year":"1999"},{"key":"ref18","series-title":"J Vet Intern Med","article-title":"Differentiating benign and malignant causes of lymphocytosis in feline bone marrow","author":"Weiss","year":"2006"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/228\/6\/javma.228.6.893.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/228\/6\/javma.228.6.893.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/228\/6\/javma.228.6.893.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T08:37:27Z","timestamp":1741336647000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/228\/6\/javma.228.6.893.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3,15]]},"references-count":18,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.2460\/javma.228.6.893","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2006,3,15]]}}}