{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T11:29:10Z","timestamp":1773055750498,"version":"3.50.1"},"reference-count":11,"publisher":"American Veterinary Medical Association (AVMA)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2006,3,15]]},"abstract":"Abstract<\/jats:title>\nObjective<\/jats:bold>\u2014To determine the efficacy of strontium 90 \u03b2 irradiation in the management of cutaneous mast cell tumors (CMCTs) in cats.<\/jats:p>\nStudy Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\nAnimals<\/jats:bold>\u201435 client-owned cats with CMCTs.<\/jats:p>\nProcedure<\/jats:bold>\u2014Medical records of cats with CMCTs in which tumors were radiated by use of a strontium 90 ophthalmic applicator from 1992 to 2002 were reviewed. Cats were included if CMCT was diagnosed, there were no other sites of MCT involvement at the time of treatment, and records contained adequate follow-up information to permit retrospective assessment of local tumor control.<\/jats:p>\nResults<\/jats:bold>\u201454 tumors in 35 cats were treated with a median dose of 135 Gy of strontium 90 \u03b2 irradiation, resulting in local tumor control in 53 of 54 (98%) tumors with a median follow-up time of 783 days after treatment. Median survival time was 1,075 days. Adverse effects of treatment appeared to be infrequent and of mild severity.<\/jats:p>\nConclusions and Clinical Relevance<\/jats:bold>\u2014Results indicated that strontium 90 \u03b2 irradiation resulted in long-term tumor control and should be considered an effective alternative to surgical resection in management of CMCTs in cats.<\/jats:p>","DOI":"10.2460\/javma.228.6.898","type":"journal-article","created":{"date-parts":[[2006,3,14]],"date-time":"2006-03-14T22:09:27Z","timestamp":1142374167000},"page":"898-901","source":"Crossref","is-referenced-by-count":31,"title":["Evaluation of strontium 90 irradiation in treatment of cutaneous mast cell tumors in cats: 35 cases (1992\u20132002)"],"prefix":"10.2460","volume":"228","author":[{"given":"Jane M.","family":"Turrel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Farrelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodney L.","family":"Page","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret C.","family":"McEntee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Anim Hosp Assoc","first-page":"21","article-title":"A retrospective study of 395 feline neoplasms","volume":"5","author":"Engle","year":"1969"},{"key":"ref2","series-title":"Cornell Vet","first-page":"87","article-title":"Feline cutaneous mastocytomas","volume":"63","author":"Holzinger","year":"1973"},{"key":"ref3","series-title":"Vet Pathol","first-page":"389","article-title":"Cutaneous neoplasia in 340 cats","volume":"28","author":"Miller","year":"1991"},{"key":"ref4","series-title":"J Am Anim Hosp Assoc","first-page":"281","article-title":"Cutaneous mast cell tumors in cats: 32 cases (1991\u20131994)","volume":"34","author":"Molander-McCrary","year":"1998"},{"issue":"3","key":"ref5","series-title":"Feline Pract","first-page":"41","article-title":"Cutaneous mastocytosis with metastases in a domestic cat","volume":"10","author":"Cohen","year":"1980"},{"key":"ref6","series-title":"Vet Pathol","first-page":"320","article-title":"The morphology and behavior of feline cutaneous mastocytomas","volume":"23","author":"Wilcock","year":"1986"},{"key":"ref7","series-title":"J Am Vet Med Assoc","first-page":"1440","article-title":"Cutaneous mast cell neoplasia in cats: 14 cases (1975\u20131985)","volume":"190","author":"Buerger","year":"1987"},{"key":"ref8","series-title":"Vet Pathol","first-page":"452","article-title":"Histopathology and biologic behavior of pleomorphic cutaneous mast cell tumors in fifteen cats","volume":"39","author":"Johnson","year":"2002"},{"key":"ref9","series-title":"Med Phys","first-page":"161","article-title":"Surface dose rate calibration of Sr-90 plane ophthalmic applicators","volume":"18","author":"Goetsch","year":"1991"},{"key":"ref10","series-title":"Med Dosim","first-page":"229","article-title":"Strontium-90 eye application","volume":"14","author":"Sharma","year":"1989"},{"issue":"suppl 1","key":"ref11","series-title":"Vet Res Commun","first-page":"707","article-title":"Diagnostic and prognostic features of feline cutaneous mast cell tumours: a retrospective analysis of 40 cases","volume":"27","author":"Lepri","year":"2003"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/228\/6\/javma.228.6.898.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/228\/6\/javma.228.6.898.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/228\/6\/javma.228.6.898.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:39:35Z","timestamp":1741354775000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/228\/6\/javma.228.6.898.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3,15]]},"references-count":11,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.2460\/javma.228.6.898","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2006,3,15]]}}}