{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:00:15Z","timestamp":1770217215327,"version":"3.49.0"},"reference-count":18,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2006,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Case Description<\/jats:bold>\u2014A 4-year-old sexually intact female French Bulldog was evaluated because of lethargy, anorexia, and chronic rhinitis-sinusitis. The dog had nasal discharge of 18 months' duration; dorsal rhinotomies were performed 3 months and 2 weeks prior to referral.<\/jats:p>\n<jats:p><jats:bold>Clinical Findings<\/jats:bold>\u2014On initial evaluation, intraventricular pneumocephalus and sinusitis were diagnosed; CSF analysis revealed high total protein concentration and mononuclear pleocytosis. The dog's condition improved with treatment. Two weeks after discharge, it was treated by a local veterinarian because of upper airway obstruction; 3 days later, the dog was referred because of seizures. Computed tomography revealed a large fluid-filled, left lateral ventricle and a soft tissue mass protruding through a cribriform plate defect. The mass was histologically consistent with brain tissue. Findings of clinicopathologic analyses were unremarkable. Results of cytologic examination of a CSF sample were indicative of septic, suppurative inflammation, and bacteriologic culture of CSF yielded <jats:italic>Escherichia coli<\/jats:italic>.<\/jats:p>\n<jats:p><jats:bold>Treatment and Outcome<\/jats:bold>\u2014Amputation of the herniated olfactory bulb and antimicrobial treatment resolved the septic meningoencephalitis, but neurologic deficits recurred 6 weeks later. Definitive correction of the cribriform plate defect with bone and fascial grafts was attempted. Postoperative rotation of the bone graft resulted in cerebral laceration and hemorrhage, and the dog was euthanized.<\/jats:p>\n<jats:p><jats:bold>Clinical Relevance<\/jats:bold>\u2014Findings suggest that following dorsal rhinotomy and nasal polypectomy surgery, the dog developed herniation of the left olfactory bulb, intra-ventricular pneumocephalus, and septic meningo-encephalitis because of a cribriform plate defect. Care must be taken to prevent rotation of bone grafts used in cribriform defect repair.<\/jats:p>","DOI":"10.2460\/javma.229.2.240","type":"journal-article","created":{"date-parts":[[2006,7,15]],"date-time":"2006-07-15T20:32:17Z","timestamp":1152995537000},"page":"240-245","source":"Crossref","is-referenced-by-count":30,"title":["Ventricular pneumocephalus and septic meningoencephalitis secondary to dorsal rhinotomy and nasal polypectomy in a dog"],"prefix":"10.2460","volume":"229","author":[{"given":"Daniel J.","family":"Fletcher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica M.","family":"Snyder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer S.","family":"Messinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander G.","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles H.","family":"Vite","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Laryngol Otol","first-page":"345","article-title":"Traumatic pneumocephalus","volume":"90","author":"Ramsden","year":"1976"},{"key":"ref2","series-title":"J Laryngol Otol","first-page":"1275","article-title":"Air in the ventricles: an unusual complication of nasal polypectomy","volume":"99","author":"Osborne","year":"1985"},{"key":"ref3","series-title":"Ann Otol Rhinol Laryngol","first-page":"576","article-title":"Pneumocephalus following nasal polypectomy","volume":"103","author":"Ophir","year":"1994"},{"key":"ref4","series-title":"Ann Otol Rhinol Laryngol","first-page":"326","article-title":"Pneumocephalus as a complication of intranasal ethmoidectomy and polypectomy","volume":"104","author":"Bendet","year":"1995"},{"key":"ref5","series-title":"J Laryngol Otol","first-page":"657","article-title":"The management of massive pneumocephalus and cerebrospinal fluid rhinorrhoea as a consequence of biopsy in a patient with inverted papilloma","volume":"112","author":"Kale","year":"1998"},{"key":"ref6","series-title":"Vet Surg","first-page":"446","article-title":"Ventral rhinotomy in the dog and cat","volume":"18","author":"Holmberg","year":"1989"},{"key":"ref7","series-title":"Can Vet J","first-page":"483","article-title":"Sequelae of ventral rhinotomy in dogs and cats with inflammatory and neoplastic nasal pathology: a retrospective study","volume":"37","author":"Holmberg","year":"1996"},{"key":"ref8","series-title":"Vet Surg","first-page":"226","article-title":"Intraventricular tension pneumocephalus as a complication of transfrontal craniectomy: a case report","volume":"31","author":"Garosi","year":"2002"},{"key":"ref9","series-title":"J Am Vet Med Assoc","first-page":"1057","article-title":"What is your diagnosis? 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A meta-analysis","volume":"123","author":"Brodie","year":"1997"},{"key":"ref15","series-title":"J Neurosurg","first-page":"757","article-title":"Prophylactic administration of ceftriaxone for the prevention of meningitis after traumatic pneumocephalus: results of a clinical trial","volume":"101","author":"Eftekhar","year":"2004"},{"key":"ref16","series-title":"Lymphology","first-page":"144","article-title":"Alternative pathways for drainage of cerebrospinal fluid in the canine brain","volume":"22","author":"Leeds","year":"1989"},{"key":"ref17","series-title":"Otolaryngol Head Neck Surg","first-page":"204","article-title":"Endoscopic repair of large skull base defects after powered sinus surgery","volume":"129","author":"Church","year":"2003"},{"key":"ref18","series-title":"Otolaryngol Head Neck Surg","first-page":"69","article-title":"Extended pericranial flap and bone graft reconstruction in anterior skull base surgery","volume":"131","author":"Rodrigues","year":"2004"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/229\/2\/javma.229.2.240.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/229\/2\/javma.229.2.240.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/229\/2\/javma.229.2.240.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:37:05Z","timestamp":1741354625000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/229\/2\/javma.229.2.240.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7,15]]},"references-count":18,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.2460\/javma.229.2.240","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2006,7,15]]}}}