{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:48:45Z","timestamp":1776732525286,"version":"3.51.2"},"reference-count":15,"publisher":"American Veterinary Medical Association (AVMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2006,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Case Description<\/jats:bold>\u2014A 6-year-old female African pygmy hedgehog was evaluated because of a mass of unknown duration on the lateral aspect of the right shoulder region.<\/jats:p>\n<jats:p><jats:bold>Clinical Findings<\/jats:bold>\u2014A fine-needle aspirate of the mass was collected for cytologic examination; findings were consistent with a spindle cell tumor. A CBC, plasma biochemical analyses, and whole-body radiography revealed no other abnormalities.<\/jats:p>\n<jats:p><jats:bold>Treatment and Outcome<\/jats:bold>\u2014An initial surgery performed in an attempt to remove the mass with preservation of the limb failed in that tumor-free surgical margins were not obtained. Histologically, the mass was identified as a peripheral nerve sheath tumor (neurofibrosarcoma). A second surgery to amputate the forelimb was successful. After 1 year, there had been no further development of peripheral nerve sheath tumor at this or other sites.<\/jats:p>\n<jats:p><jats:bold>Clinical Relevance<\/jats:bold>\u2014In African pygmy hedgehogs, potential differential diagnoses for a subcutaneous mass should include peripheral nerve sheath tumor. If necessary, forelimb amputation can be performed successfully in this species with procedures modified from those used in dogs. Information gathered during the treatment and recovery of the hedgehog of this report may assist practicing veterinarians in counseling owners of hedgehogs that are undergoing forelimb amputation with regard to the course of recovery that may be expected following this procedure.<\/jats:p>","DOI":"10.2460\/javma.229.5.706","type":"journal-article","created":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T13:54:45Z","timestamp":1157118885000},"page":"706-710","source":"Crossref","is-referenced-by-count":12,"title":["Forelimb amputation for treatment of a peripheral nerve sheath tumor in an African pygmy hedgehog"],"prefix":"10.2460","volume":"229","author":[{"given":"Kacie K.","family":"Martin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew S.","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Exotic animal formulary","first-page":"368","author":"Carpenter","year":"2005"},{"key":"ref2","series-title":"Ferrets, rabbits, and rodents: clinical medicine and surgery","first-page":"344","article-title":"African hedgehogs","author":"Ivey","year":"2004"},{"key":"ref3","series-title":"Cancer","first-page":"530","article-title":"The grading of soft tissue sarcomas. Results of a clinicohistopathologic correlation in a series of 163 cases","volume":"53","author":"Costa","year":"1984"},{"key":"ref4","series-title":"Small animal surgery","volume":"1177","author":"Fossum","year":"2002"},{"key":"ref5","series-title":"J Am Anim Hosp Assoc","first-page":"349","article-title":"A retrospective evaluation of 51 cases of peripheral nerve sheath tumors in the dog","volume":"31","author":"Brehm","year":"1995"},{"key":"ref6","series-title":"J Am Anim Hosp Assoc","first-page":"915","article-title":"Nerve sheath tumors in the dog","volume":"18","author":"Bradley","year":"1982"},{"key":"ref7","series-title":"Vet Ophthalmol","first-page":"153","article-title":"Feline periocular peripheral nerve sheath tumor: a case series","volume":"8","author":"Hoffman","year":"2005"},{"key":"ref8","series-title":"J Am Vet Med Assoc","first-page":"1147","article-title":"Prognostic factors for surgical treatment of soft-tissue sarcomas in dogs: 75 cases (1986\u20131996)","volume":"211","author":"Kuntz","year":"1997"},{"key":"ref9","series-title":"J Am Vet Med Assoc","first-page":"1140","article-title":"Removal of a thymoma via median sternotomy in a rabbit with recurrent appendicular neurofibrosarcoma","volume":"213","author":"Clippinger","year":"1998"},{"key":"ref10","series-title":"Tufts Animal Expo Online Proceedings 2002","article-title":"Diseases and medicine of the African hedgehog","author":"Carpenter"},{"key":"ref11","series-title":"J Vet Diagn Invest","first-page":"442","article-title":"Soft tissue sarcomas in the African hedgehog (Atelerix albiventris): microscopic and immunohistologic study of three cases","volume":"13","author":"Ramos-Vara","year":"2001"},{"key":"ref12","series-title":"Aust Vet J","first-page":"222","article-title":"Diagnosis and excision of a brachial plexus nerve sheath tumour in a dog","volume":"77","author":"Simpson","year":"1999"},{"key":"ref13","series-title":"J Comp Pathol","first-page":"87","article-title":"Epithelioid malignant peripheral nerve sheath tumour in a dog","volume":"131","author":"Garcia","year":"2004"},{"key":"ref14","series-title":"Vet Pathol","first-page":"679","article-title":"Point mutation of neu oncogene in animal peripheral nerve sheath tumors","volume":"38","author":"Stoica","year":"2001"},{"key":"ref15","series-title":"Spine","first-page":"752","article-title":"Malignant spinal neurofibrosarcoma","volume":"25","author":"Kett-White","year":"2000"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/229\/5\/javma.229.5.706.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/229\/5\/javma.229.5.706.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/229\/5\/javma.229.5.706.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:56:58Z","timestamp":1741355818000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/229\/5\/javma.229.5.706.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9,1]]},"references-count":15,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.2460\/javma.229.5.706","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2006,9,1]]}}}