{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:06:42Z","timestamp":1753888002534,"version":"3.38.0"},"reference-count":17,"publisher":"American Veterinary Medical Association (AVMA)","issue":"11","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2023,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Cranial cruciate ligament disease (CCLD) is the most prevalent orthopedic problem in canines, affecting 3% to 5% of dogs, causing stifle instability, mobility dysfunction, and pain. The objective of this study was to evaluate the American Kennel Club field trial community\u2019s knowledge of CCLD and estimate its perceived prevalence within this population.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>SAMPLE<\/jats:title>\n<jats:p>401 field trial participants responded, with 701 field trial canines reported.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>A survey instrument was emailed to a population of Retriever field trial participants to collect information on perceptions and experience with CCLD and current canine participants. Analyses included descriptive statistics, multiple logistic regression, and \u03c7<jats:sup>2<\/jats:sup> tests (significant at <jats:italic>P<\/jats:italic> &lt; .05).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>The majority of respondents appropriately identified the connection between genetics and CCLD (69%). There was under-recognition (6%) of the degenerative nature of the disease, with 61% inappropriately identifying trauma as the major cause. Respondents also indicated that a CCLD diagnosis in a dog\u2019s sibling or offspring affected their breeding decisions less than a diagnosis in their parents, indicating a misunderstanding of genetics. More than half of respondents indicated prior experiences with CCLD. The reported occurrence of CCLD was found to be 12% (72\/610) in field trial Labrador Retrievers.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>There is a lack of knowledge in the field trial community regarding CCLD. This population showed a higher owner-perceived occurrence of CCLD compared to data collected from medical records. Further investigation is warranted to validate the true prevalence of CCLD in field trial Retrievers.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.23.01.0004","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T17:37:32Z","timestamp":1689356252000},"page":"1-6","source":"Crossref","is-referenced-by-count":5,"title":["Cranial cruciate ligament disease is perceived to be prevalent and is misunderstood in field trial sport"],"prefix":"10.2460","volume":"261","author":[{"given":"Jessica","family":"Hynes","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane M.","family":"Manfredi","sequence":"additional","affiliation":[{"name":"Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah A.","family":"Shull","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"issue":"10","key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"1604","article-title":"Estimate of the annual economic impact of treatment of cranial cruciate ligament injury in dogs in the United States","volume":"227","author":"Wilke VL","year":"2005","unstructured":"Wilke VL, Robinson DA, Evans RB, Rothschild MF, Conzemius MG. Estimate of the annual economic impact of treatment of cranial cruciate ligament injury in dogs in the United States. J Am Vet Med Assoc. 2005;227(10):1604-1607. doi:10.2460\/javma.2005.227.1604"},{"key":"ref2","unstructured":"Retriever field trials. About. American Kennel Club. Updated October 26, 2017. Accessed July 2, 2020. https:\/\/www.akc.org\/sports\/retrievers\/field-trials\/about\/","article-title":"American Kennel Club"},{"key":"ref3","series-title":"Working Labrador Retrievers","article-title":"Glossary of Retriever training, field trial and hunt test terms","author":"Schoor HM","unstructured":"Schoor HM. Glossary of Retriever training, field trial and hunt test terms. Working Labrador Retrievers. Henny M. Schoor. Updated April 7, 2007. Accessed July 2, 2020. www.hennymschoor.nl\/Artikelen\/Retriever_Glossary___Terminology.pdf"},{"key":"ref4","series-title":"Golden Retriever Club of America","article-title":"A guide to field trial stakes","author":"Pickering J","unstructured":"Pickering J. A guide to field trial stakes. Golden Retriever Club of America. Updated August 20, 2015. Accessed July 2, 2020. https:\/\/grca.org\/events\/field-events-field-training\/akc-licensed-field-trials\/a-guide-to-field-trial-stakes-jim-pickering\/"},{"issue":"4","key":"ref5","series-title":"N Z Vet J","first-page":"149","article-title":"Cranial cruciate ligament injury in the dog: pathophysiology, diagnosis and treatment","volume":"51","author":"Jerram RM","year":"2003","unstructured":"Jerram RM, Walker AM. Cranial cruciate ligament injury in the dog: pathophysiology, diagnosis and treatment. N Z Vet J. 2003;51(4):149-158. doi:10.1080\/00480169.2003.36357"},{"issue":"6","key":"ref6","series-title":"Aust Vet J","first-page":"220","article-title":"Retrospective analysis of complications and outcomes in Boxers and Staffordshire Bull Terriers undergoing cranial cruciate ligament surgery","volume":"91","author":"Levien AS","year":"2013","unstructured":"Levien AS, Brodbelt DC, Arthurs GI. Retrospective analysis of complications and outcomes in Boxers and Staffordshire Bull Terriers undergoing cranial cruciate ligament surgery. Aust Vet J. 2013;91(6):220-225. doi:10.1111\/avj.12062"},{"issue":"4","key":"ref7","series-title":"Vet Surg","first-page":"399","article-title":"A review of the pathogenesis of canine cranial cruciate ligament disease as a basis for future preventive strategies","volume":"39","author":"Griffon DJ","year":"2010","unstructured":"Griffon DJ. A review of the pathogenesis of canine cranial cruciate ligament disease as a basis for future preventive strategies. Vet Surg. 2010;39(4):399-409. doi:10.1111\/j.1532-950X.2010.00654.x"},{"issue":"5","key":"ref8","series-title":"J Am Anim Hosp Assoc","first-page":"385","article-title":"Cranial cruciate ligament pathophysiology in dogs with cruciate disease: a review","volume":"40","author":"Hayashi K","year":"2004","unstructured":"Hayashi K, Manley PA, Muir P. Cranial cruciate ligament pathophysiology in dogs with cruciate disease: a review. J Am Anim Hosp Assoc. 2004;40(5):385-390. doi:10.5326\/0400385"},{"issue":"2","key":"ref9","series-title":"Vet Comp Orthop Traumatol","first-page":"91","article-title":"Update on the aetiopathogenesis of canine cranial cruciate ligament disease","volume":"24","author":"Comerford EJ","year":"2011","unstructured":"Comerford EJ, Smith K, Hayashi K. Update on the aetiopathogenesis of canine cranial cruciate ligament disease. Vet Comp Orthop Traumatol. 2011;24(2):91-98. doi:10.3415\/VCOT-10-04-0055"},{"issue":"5","key":"ref10","series-title":"J Am Anim Hosp Assoc","first-page":"315","article-title":"Systematic review of surgical treatments for cranial cruciate ligament disease in dogs","volume":"50","author":"Bergh MS","year":"2014","unstructured":"Bergh MS, Sullivan C, Ferrell CL, Troy J, Budsberg SC. Systematic review of surgical treatments for cranial cruciate ligament disease in dogs. J Am Anim Hosp Assoc. 2014;50(5):315-321. doi:10.5326\/JAAHA-MS-6356"},{"issue":"3","key":"ref11","series-title":"Vet Radiol Ultrasound","first-page":"280","article-title":"Stifle joint osteoarthritis at the time of diagnosis of cranial cruciate ligament injury is higher in Boxers and in dogs weighing more than 35 kilograms","volume":"60","author":"Gilbert S","year":"2019","unstructured":"Gilbert S, Langenbach A, Marcellin-Little DJ, Pease AP, Ru H. Stifle joint osteoarthritis at the time of diagnosis of cranial cruciate ligament injury is higher in Boxers and in dogs weighing more than 35 kilograms. Vet Radiol Ultrasound. 2019;60(3):280-288. doi:10.1111\/vru.12718"},{"key":"ref12","series-title":"Canine Genet Epidemiol","first-page":"6","article-title":"Correlation of neuter status and expression of heritable disorders","volume":"4","author":"Belanger JM","year":"2017","unstructured":"Belanger JM, Bellumori TP, Bannasch DL, Famula TR, Oberbauer AM. Correlation of neuter status and expression of heritable disorders. Canine Genet Epidemiol. 2017;4:6. doi:10.1186\/s40575-017-0044-6"},{"issue":"12","key":"ref13","series-title":"J Am Vet Med Assoc","first-page":"1818","article-title":"Prevalence of and risk factors for hip dysplasia and cranial cruciate ligament deficiency in dogs","volume":"232","author":"Witsberger TH","year":"2008","unstructured":"Witsberger TH, Villamil JA, Schultz LG, Hahn AW, Cook JL. Prevalence of and risk factors for hip dysplasia and cranial cruciate ligament deficiency in dogs. J Am Vet Med Assoc. 2008;232(12):1818-1824. doi:10.2460\/javma.232.12.1818"},{"issue":"6","key":"ref14","series-title":"Vet Surg","first-page":"777","article-title":"Epidemiology of cranial cruciate ligament disease diagnosis in dogs attending primary-care veterinary practices in England","volume":"44","author":"Taylor-Brown FE","year":"2015","unstructured":"Taylor-Brown FE, Meeson RL, Brodbelt DC,  Epidemiology of cranial cruciate ligament disease diagnosis in dogs attending primary-care veterinary practices in England. Vet Surg. 2015;44(6):777-783. doi:10.1111\/vsu.12349"},{"issue":"1","key":"ref15","series-title":"Acta Vet Scand","first-page":"19","article-title":"Breed susceptibility for common surgically treated orthopaedic diseases in 12 dog breeds (published correction appears in","volume":"61","author":"Boge GS","year":"2019","unstructured":"Boge GS, Moldal ER, Dimopoulou M, Skjerve E, Bergstr\u00f6m A. Breed susceptibility for common surgically treated orthopaedic diseases in 12 dog breeds (published correction appears in Acta Vet Scand. 2020;62[1]:10). Acta Vet Scand. 2019;61(1):19. doi:10.1186\/s13028-019-0454-4"},{"issue":"6","key":"ref16","series-title":"Vet Comp Orthop Traumatol","first-page":"473","article-title":"Return to sport after injury: a web-based survey of owners and handlers of agility dogs","volume":"31","author":"Tomlinson JE","year":"2018","unstructured":"Tomlinson JE, Manfredi JM. Return to sport after injury: a web-based survey of owners and handlers of agility dogs. Vet Comp Orthop Traumatol. 2018;31(6):473-478. doi:10.1055\/s-0038-1670676"},{"issue":"5","key":"ref17","series-title":"Anim Genet","first-page":"824","article-title":"SNP-based heritability and genetic architecture of cranial cruciate ligament rupture in Labrador Retrievers","volume":"51","author":"Cook SR","year":"2020","unstructured":"Cook SR, Conzemius MG, McCue ME, Ekenstedt KJ. SNP-based heritability and genetic architecture of cranial cruciate ligament rupture in Labrador Retrievers. Anim Genet. 2020;51(5):824-828. doi:10.1111\/age.12978"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/261\/11\/javma.23.01.0004.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/261\/11\/javma.23.01.0004.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/261\/11\/javma.23.01.0004.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:03:34Z","timestamp":1741352614000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/261\/11\/javma.23.01.0004.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,1]]},"references-count":17,"journal-issue":{"issue":"11"},"URL":"https:\/\/doi.org\/10.2460\/javma.23.01.0004","relation":{},"ISSN":["0003-1488"],"issn-type":[{"type":"print","value":"0003-1488"}],"subject":[],"published":{"date-parts":[[2023,11,1]]}}}