{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:54:00Z","timestamp":1787025240764,"version":"build-2736575974"},"reference-count":30,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2023,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To describe clinical findings, diagnosis, treatment, and survival in 18 cats with anemia of suspected immune-mediated origin (ASIMO) and conflicting results using FeLV diagnosis tests, and to suggest an accurate way to assess their FeLV diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>ANIMALS<\/jats:title>\n                    <jats:p>18 cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROCEDURES<\/jats:title>\n                    <jats:p>Medical records from 5 veterinary institutions were retrospectively reviewed to identify cats with ASIMO, positive results on p27 SNAP ELISA, and negative results on pro-virus PCR testing in peripheral blood, in the absence of other identified triggers. Follow-up was recorded from diagnosis to the time of writing, and survival analysis was performed to assess similarities with previous published data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>18 cats were enrolled from referral centers in Spain, Italy, and the United Kingdom. Both peripheral immune-mediated hemolytic anemia (IMHA; 12\/18) and precursor targeted immune-mediated anemia (PIMA; 6\/18) were described. When the SNAP ELISA test was rechecked in patients with disease control, SNAP ELISA positive results had become negative. Two cats had a relapse of the ASIMO, and the FeLV SNAP ELISA tested positive again. Other signs of FeLV disease did not appear in any of these patients despite immunosuppression. 14 cats (14\/18 [78%]) were alive at the time of writing, and the mean estimated survival time was 769 days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CLINICAL RELEVANCE<\/jats:title>\n                    <jats:p>This study describes incongruent FeLV results in cats with ASIMO. It supports the necessity to confirm FeLV SNAP ELISA positive results using additional tools, such as pro-virus PCR testing, as different p27 point-of-care and external serological tests may be inconsistent.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/javma.23.02.0059","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T10:10:18Z","timestamp":1689675018000},"page":"1459-1465","source":"Crossref","is-referenced-by-count":8,"title":["A retrospective review of cats with suspected false positive results in point-of-care feline leukemia virus tests and concurrent immune-mediated anemia"],"prefix":"10.2460","volume":"261","author":[{"given":"Laura Izquierdo","family":"Robert","sequence":"first","affiliation":[{"name":"Internal Medicine Department, AniCura Ars Veterin\u00e0ria, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Puig","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, AniCura Ars Veterin\u00e0ria, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Tumbarello","sequence":"additional","affiliation":[{"name":"Veterinary Medical Science Department, University of Bolognia, Ozzano dell\u2019Emilia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Farigola","sequence":"additional","affiliation":[{"name":"Critical Care Department, AniCura Hospital Veterinari Gl\u00f2ries, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayank","family":"Seth","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, KGS Veterinary Service, Saffron Walden, Essex, England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Mesa","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Paterna, Valencia, Spain"},{"name":"Animal Blood Bank, Passatge de Rovira i Virgili, Sabadell, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Feo","family":"Bernabe","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, AniCura Ars Veterin\u00e0ria, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"9","key":"ref1","series-title":"J Feline Med Surg","first-page":"831","article-title":"Feline leukaemia virus infection: a practical approach to diagnosis","volume":"22","author":"Hofmann-Lehmann R","year":"2020","unstructured":"Hofmann-Lehmann R, Hartmann K. 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