{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:44:46Z","timestamp":1787312686022,"version":"build-2736575974"},"reference-count":16,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>To assess the therapeutic efficacy of acupuncture in combination with Chinese herbs for treatment of horses affected with anhidrosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>ANIMALS<\/jats:title>\n                    <jats:p>44 horses affected with anhidrosis for up to 3 years\u2019 duration were enrolled. Inclusion required both compatible clinical signs and results of a quantitative intradermal terbutaline sweat test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Study horses were randomly allocated into 2 groups. Group 1 (n = 19) was treated with daily Chinese herbs and 4 weekly acupuncture sessions. Group 2 (n = 25) was given daily hay powder as a placebo and 4 weekly sham acupuncture sessions. Horses were tested by quantitative intradermal terbutaline sweat test within 2 days after treatment completion and again 4 weeks following treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Terbutaline-induced sweat responses (mg) were not different between groups within 2 days and 4 weeks after treatment. Two days after treatment, ratios of sweat responses (compared to baseline) were higher (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .05) in the treatment group compared to the placebo group at terbutaline concentrations of 1.0, 100, and 1,000 \u00b5g\/mL. The number of horses responding to treatment was higher in the treatment group (5\/19 [26%]), compared to horses in the placebo group (1\/25 [4%]) for 1 of 5 terbutaline concentrations 2 days (10 \u00b5g\/mL) or 4 weeks (0.1 \u00b5g\/mL) after treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CLINICAL RELEVANCE<\/jats:title>\n                    <jats:p>Ratios of sweat responses were higher in treatment horses 2 days after treatment, compared to baseline, but not 4 weeks later. The efficacy of a traditional Chinese veterinary medicine protocol for anhidrosis treatment with acupuncture and Chinese herbs was low but higher in treated horses compared with placebo.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2460\/javma.23.08.0474","type":"journal-article","created":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T12:34:02Z","timestamp":1701866042000},"page":"1-6","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of treatment of equine anhidrosis with acupuncture and Chinese herbs is low but higher in treated horses compared with placebo"],"prefix":"10.2460","volume":"262","author":[{"given":"Martha F.","family":"Mallicote","sequence":"first","affiliation":[{"name":"Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina I.","family":"Medina","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Zilberschtein","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL"},{"name":"Department of Animal Medicine and Surgery, University of Murcia, Murcia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacie","family":"Atria","sequence":"additional","affiliation":[{"name":"Lotus Veterinary Alternatives, Gainesville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Manzie","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge A.","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"MacKay","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"1","key":"ref1","series-title":"Vet Dermatol","first-page":"2","article-title":"Equine sweating and anhidrosis. 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Acupuncture treatment for miscellaneous conditions in horses. In: Schoen AM, ed. Veterinary Acupuncture. 2nd ed. Mosby; 2001:481-487."},{"key":"ref15","series-title":"Master\u2019s thesis","article-title":"Response of Anhidrotic Horses to Nutrient Supplementation","author":"Bowker KD","year":"1995","unstructured":"Bowker KD. Response of Anhidrotic Horses to Nutrient Supplementation. Master\u2019s thesis. University of Florida; 1995."},{"issue":"1","key":"ref16","series-title":"Chin Med","first-page":"4","article-title":"Point specificity in acupuncture","volume":"7","author":"Choi EM","year":"2012","unstructured":"Choi EM, Jiang F, Longhurst JC. Point specificity in acupuncture. 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