{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T14:20:40Z","timestamp":1784125240529,"version":"3.55.0"},"reference-count":23,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To describe the signalment, clinical findings, presumptive or definitive diagnosis, and outcome in cats with central cord syndrome (CCS).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>ANIMALS<\/jats:title>\n<jats:p>22 cats.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL PRESENTATION<\/jats:title>\n<jats:p>Cats evaluated for CCS at 7 referral hospitals between 2017 and 2021 were included. Information retrieved from medical records included signalment, physical and neurological examination findings, diagnostic investigations, definitive or presumptive diagnosis, treatment, and follow-up.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Median age at presentation was 9 years. Two neuroanatomical localizations were associated with CCS: C1-C5 spinal cord segments in 17 (77.3%) cats and C6-T2 spinal cord segments in 5 (22.7%) cats. Neuroanatomical localization did not correlate with lesion location on MRI in 8 (36.3%) cats. The most common lesion location within the vertebral column was over the C2 and C4 vertebral bodies in 6 (27.2%) and 5 (22.7%) cats, respectively. Peracute clinical signs were observed in 11 (50%) cats, acute in 1 (4.5%), subacute in 4 (18%), and chronic and progressive signs were seen in 6 (40.9%) cats. The most common peracute condition was ischemic myelopathy in 8 (36.3%) cats, whereas neoplasia was the most frequently identified chronic etiology occurring in 5 (22.7%) cats. Outcome was poor in 13 (59%) cats, consisting of 4 of 11 (36.6%) of the peracute cases, 3 of 4 (75%) of the subacute cases, and 6 of 6 of the chronic cases.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>Central cord syndrome can occur in cats with lesions in the C1-C5 and C6-T2 spinal cord segments. Multiple etiologies can cause CCS, most commonly, ischemic myelopathy and neoplasia. Prognosis depends on the etiology and onset of clinical signs.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.23.08.0478","type":"journal-article","created":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T17:33:54Z","timestamp":1701884034000},"page":"405-410","source":"Crossref","is-referenced-by-count":2,"title":["Clinical signs, causes, and outcome of central cord syndrome in 22 cats"],"prefix":"10.2460","volume":"262","author":[{"given":"Carlos","family":"Ros","sequence":"first","affiliation":[{"name":"Neurology and Neurosurgery Service, Memvet Referral Center, Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Jos\u00e9-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Small Animal Hospital, School of Veterinary Medicine, University of Glasgow, Scotland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Font","sequence":"additional","affiliation":[{"name":"Hospital Veterinari Canis, Girona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Su\u00f1ol","sequence":"additional","affiliation":[{"name":"Hospital for Small Animals, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Scotland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emili","family":"Alcoverro","sequence":"additional","affiliation":[{"name":"Chestergates Veterinary Specialists, Chester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmin","family":"Nessler","sequence":"additional","affiliation":[{"name":"Department of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Garc\u00eda de Carell\u00e1n Mateo","sequence":"additional","affiliation":[{"name":"Anaesthesia and Analgesia Service, Memvet Referral Center, Palma de Mallorca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente","family":"Aige","sequence":"additional","affiliation":[{"name":"Departamento de Sanidad y Anatom\u00eda Animal, Universidad Aut\u00f3noma de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Department of Veterinary Science, Small Animal Teaching Hospital, University of Liverpool, Neston, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"5","key":"ref1","series-title":"Vet Clin North Am Small Anim Pract","first-page":"1011","article-title":"Feline spinal cord diseases","volume":"40","author":"Marioni-Henry K","year":"2010","unstructured":"Marioni-Henry K. 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