{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:19:02Z","timestamp":1784546342588,"version":"3.55.0"},"reference-count":16,"publisher":"American Veterinary Medical Association (AVMA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To describe the intestinal full-thickness needle-core biopsy technique via abdominal laparotomy outcomes and compare the histopathological and immunohistochemical diagnosis with standard incisional intestinal biopsy technique in dogs and cats.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>ANIMALS<\/jats:title>\n<jats:p>3 dogs and 17 cats.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>Client-owned dogs and cats were prospectively enrolled if intestinal full-thickness biopsies were indicated for the diagnosis of diffuse chronic intestinal diseases following ultrasonography. The study period extended from June 2021 to December 2022. All animals underwent intestinal biopsies with both techniques (needle-core biopsy and standard incisional biopsy) via abdominal laparotomy. Data collected included clinical signs, biopsy collection times, complications, and histopathologic and immunohistochemical findings. A minimum follow-up of 14 days was required.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>The main clinical sign at presentation was chronic vomiting (65%). Mean needle-core biopsy collection time (262 seconds) was significantly shorter than standard incisional biopsy collection time (599 seconds; <jats:italic>P<\/jats:italic> &lt; .000001). The incidence of minor complications was 10% (inflammation of the skin surgical site secondary to licking). One catastrophic complication occurred on a standard incisional biopsy site in 1 cat in a context of bile peritonitis (5% of all cases). There were no complications associated with the needle-core biopsy. All but 1 cat were discharged, with a median of 2 days (range, 1 to 4 days) after surgery. The diagnoses resulting from both techniques were 100% concordant for the distinction between inflammatory bowel disease and intestinal lymphoma via histopathology and immunochemistry.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>Needle-core biopsy is safe, rapid, and effective and is less invasive than standard incisional biopsy.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.23.09.0521","type":"journal-article","created":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T18:50:51Z","timestamp":1702061451000},"page":"1-7","source":"Crossref","is-referenced-by-count":3,"title":["Intestinal full-thickness needle-core biopsy via laparotomy is safe, rapid, and effective and less invasive than standard incisional biopsy in dogs and cats"],"prefix":"10.2460","volume":"262","author":[{"given":"Adrien","family":"Maggiar","sequence":"first","affiliation":[{"name":"Centre Hospitalier V\u00e9t\u00e9rinaire Atlantia, Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliette","family":"Andr\u00e9jak-B\u00e9nit","sequence":"additional","affiliation":[{"name":"Statibio, Saint-Fuscien, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Miclard","sequence":"additional","affiliation":[{"name":"IHP V\u00e9to, Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Sarran","sequence":"additional","affiliation":[{"name":"Centre Hospitalier V\u00e9t\u00e9rinaire Atlantia, Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Philippe","family":"Billet","sequence":"additional","affiliation":[{"name":"Centre Hospitalier V\u00e9t\u00e9rinaire Atlantia, Nantes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"1","key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"78","article-title":"Evaluation of minimally invasive small intestinal exploration and targeted abdominal organ biopsy with use of a wound retraction device in dogs: 27 cases (2010-2017)","volume":"255","author":"Shamir SK","year":"2019","unstructured":"Shamir SK, Singh A, Mayhew PD,  Evaluation of minimally invasive small intestinal exploration and targeted abdominal organ biopsy with use of a wound retraction device in dogs: 27 cases (2010-2017). J Am Vet Med Assoc. 2019;255(1):78-84. doi:10.2460\/javma.255.1.78"},{"issue":"7","key":"ref2","series-title":"Vet Surg","first-page":"925","article-title":"Minimally invasive small intestinal exploration and targeted abdominal organ biopsy with a wound retraction device in 42 cats (2005-2015)","volume":"46","author":"Baron J","year":"2017","unstructured":"Baron J, Giuffrida M, Mayhew PD,  Minimally invasive small intestinal exploration and targeted abdominal organ biopsy with a wound retraction device in 42 cats (2005-2015). Vet Surg. 2017;46(7):925-932. doi:10.1111\/vsu.12693"},{"issue":"4","key":"ref3","series-title":"Vet Surg","first-page":"289","article-title":"Complications of small intestinal biopsy in hypoalbuminemic dogs","volume":"19","author":"Harvey HJ","year":"1990","unstructured":"Harvey HJ. Complications of small intestinal biopsy in hypoalbuminemic dogs. Vet Surg. 1990;19(4):289-292. doi:10.1111\/j.1532-950X.1990.tb01188.x"},{"issue":"7","key":"ref4","series-title":"J Small Anim Pract","first-page":"317","article-title":"Complications following full-thickness small intestinal biopsy in 66 dogs: a retrospective study","volume":"46","author":"Shales CJ","year":"2005","unstructured":"Shales CJ, Warren J, Anderson DM, Baines SJ, White RA. Complications following full-thickness small intestinal biopsy in 66 dogs: a retrospective study. J Small Anim Pract. 2005;46(7):317-321. doi:10.1111\/j.1748-5827.2005.tb00326.x"},{"issue":"5","key":"ref5","series-title":"J Am Anim Hosp Assoc","first-page":"405","article-title":"Investigation of Keyes skin biopsy instrument for intestinal biopsy versus a standard biopsy technique","volume":"40","author":"Keats MM","year":"2004","unstructured":"Keats MM, Weeren R, Greenlee P, Evans KL, Minihan AC. Investigation of Keyes skin biopsy instrument for intestinal biopsy versus a standard biopsy technique. J Am Anim Hosp Assoc. 2004;40(5):405-410. doi:10.5326\/0400405"},{"issue":"9","key":"ref6","series-title":"J Am Vet Med Assoc","first-page":"1447","article-title":"Comparison of endoscopic and full-thickness biopsy specimens for diagnosis of inflammatory bowel disease and alimentary tract lymphoma in cats","volume":"229","author":"Evans SE","year":"2006","unstructured":"Evans SE, Bonczynski JJ, Broussard JD, Han E, Baer KE. Comparison of endoscopic and full-thickness biopsy specimens for diagnosis of inflammatory bowel disease and alimentary tract lymphoma in cats. J Am Vet Med Assoc. 2006;229(9):1447-1450. doi:10.2460\/javma.229.9.1447"},{"issue":"2","key":"ref7","series-title":"J Small Anim Pract","first-page":"114","article-title":"Assessment of the clinical usefulness of ultrasound-guided cytological specimens obtained from gastrointestinal lesions in dogs and cats","volume":"62","author":"Turner RBS","year":"2021","unstructured":"Turner RBS, Liffman R, Woodward AP, Beck C, Courtman N, Dandrieux JRS. Assessment of the clinical usefulness of ultrasound-guided cytological specimens obtained from gastrointestinal lesions in dogs and cats. J Small Anim Pract. 2021;62(2):114-122. doi:10.1111\/jsap.13260"},{"issue":"1","key":"ref8","series-title":"J Vet Intern Med","first-page":"80","article-title":"Comparison of histopathologic findings in biopsies from the duodenum and ileum of dogs with enteropathy","volume":"24","author":"Casamian-Sorrosal D","year":"2010","unstructured":"Casamian-Sorrosal D, Willard MD, Murray JK, Hall EJ, Taylor SS, Day MJ. Comparison of histopathologic findings in biopsies from the duodenum and ileum of dogs with enteropathy. J Vet Intern Med. 2010;24(1):80-83. doi:10.1111\/j.1939-1676.2009.0427.x"},{"issue":"2","key":"ref9","series-title":"Vet Clin North Am","first-page":"311","article-title":"Needle biopsy of the spleen","volume":"4","author":"Osborne CA","year":"1974","unstructured":"Osborne CA, Perman V, Stevens JB. Needle biopsy of the spleen. Vet Clin North Am. 1974;4(2):311-316. doi:10.1016\/S0091-0279(74)50032-2"},{"issue":"7","key":"ref10","series-title":"J Am Vet Med Assoc","first-page":"1007","article-title":"Thymoma in dogs: 23 cases (1980-1991)","volume":"205","author":"Atwater SW","year":"1994","unstructured":"Atwater SW, Powers BE, Park RD, Straw RC, Ogilvie GK, Withrow SJ. Thymoma in dogs: 23 cases (1980-1991). J Am Vet Med Assoc. 1994;205(7):1007-1013."},{"issue":"3","key":"ref11","series-title":"Vet Radiol Ultrasound","first-page":"294","article-title":"Ultrasound-guided tissue-core biopsy of liver, spleen and kidney in normal dogs","volume":"40","author":"de Rycke LM","year":"1999","unstructured":"de Rycke LM, van Bree HJ, Simoens PJ. Ultrasound-guided tissue-core biopsy of liver, spleen and kidney in normal dogs. Vet Radiol Ultrasound. 1999;40(3):294-299. doi:10.1111\/j.1740-8261.1999.tb00364.x"},{"issue":"1","key":"ref12","series-title":"J Vet Intern Med","first-page":"10","article-title":"World Small Animal Veterinary Association International Gastrointestinal Standardization Group. Endoscopic, biopsy, and histopathologic guidelines for the evaluation of gastrointestinal inflammation in companion animals","volume":"24","author":"Washabau RJ","year":"2010","unstructured":"Washabau RJ, Day MJ, Willard MD, ; World Small Animal Veterinary Association International Gastrointestinal Standardization Group. Endoscopic, biopsy, and histopathologic guidelines for the evaluation of gastrointestinal inflammation in companion animals. J Vet Intern Med. 2010;24(1):10-26. doi:10.1111\/j.1939-1676.2009.0443.x"},{"issue":"20","key":"ref13","series-title":"Blood","first-page":"2375","article-title":"The 2016 revision of the World Health Organization classification of lymphoid neoplasms","volume":"127","author":"Swerdlow SH","year":"2016","unstructured":"Swerdlow SH, Campo E, Pileri SA,  The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016;127(20):2375-2390. doi:10.1182\/blood-2016-01-643569"},{"issue":"4","key":"ref14","series-title":"J Am Coll Surg","first-page":"364","article-title":"A multivariate analysis of factors contributing to leakage of intestinal anastomoses","volume":"184","author":"Golub R","year":"1997","unstructured":"Golub R, Golub RW, Cantu R Jr, Stein HD. A multivariate analysis of factors contributing to leakage of intestinal anastomoses. J Am Coll Surg. 1997;184(4):364-372."},{"issue":"1","key":"ref15","series-title":"J Am Vet Med Assoc","first-page":"73","article-title":"Risk factors for leakage following intestinal anastomosis in dogs and cats: 115 cases (1991-2000)","volume":"223","author":"Ralphs SC","year":"2003","unstructured":"Ralphs SC, Jessen CR, Lipowitz AJ. Risk factors for leakage following intestinal anastomosis in dogs and cats: 115 cases (1991-2000). J Am Vet Med Assoc. 2003;223(1):73-77. doi:10.2460\/javma.2003.223.73"},{"issue":"3","key":"ref16","series-title":"J Vet Intern Med","first-page":"794","article-title":"ACVIM consensus statement guidelines on diagnosing and distinguishing low-grade neoplastic from inflammatory lymphocytic chronic enteropathies in cats","volume":"37","author":"Marsilio S","year":"2023","unstructured":"Marsilio S, Freiche V, Johnson E,  ACVIM consensus statement guidelines on diagnosing and distinguishing low-grade neoplastic from inflammatory lymphocytic chronic enteropathies in cats. J Vet Intern Med. 2023;37(3):794-816. doi:10.1111\/jvim.16690"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/262\/4\/javma.23.09.0521.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/262\/4\/javma.23.09.0521.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/262\/4\/javma.23.09.0521.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T21:51:24Z","timestamp":1727301084000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/262\/4\/javma.23.09.0521.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,1]]},"references-count":16,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.2460\/javma.23.09.0521","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4,1]]}}}