{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T10:30:48Z","timestamp":1769077848812,"version":"3.49.0"},"reference-count":5,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To describe the clinical presentation, novel surgical approach, and outcome of a dog diagnosed with chondro-osseous respiratory epithelial adenomatoid hamartoma (COREAH).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>ANIMAL<\/jats:title>\n<jats:p>5-year-old castrated male Yorkshire Terrier.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES<\/jats:title>\n<jats:p>The dog was presented with chronic upper respiratory noise, congestion, facial swelling, ocular discharge, and an abscess on the nasal bridge. Two CT scans were performed 4 months apart. The CT scans yielded similar results: cyst-like nasal masses with severely destructive bilateral rhinitis with extensive polyostotic bony lysis. A dorsal rhinotomy with a turbinectomy and debridement of the nasal cavity were performed. A poorly defined but extensive lesion was found occupying the entirety of the left frontal sinus as well as the nasal cavity.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>TREATMENT AND OUTCOME<\/jats:title>\n<jats:p>Histopathology revealed a mass consistent with COREAH. The dog recovered well from surgery, except for self-limiting subcutaneous emphysema, and 3 weeks postoperatively was reportedly doing well, with mild nasal discharge. Stridor, nasal discharge, and sneezing episodes were reported postoperatively; however, these were improved. At 18 months postoperatively, the dog died from uncontrolled seizures while hospitalized for suspected acute hemorrhagic diarrhea syndrome at a different hospital.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>COREAH should be considered a potential cause of destructive bilateral rhinitis and bony lysis in dogs. Dorsal rhinotomy can be a surgical treatment for dogs with possible COREAH with acceptable outcome, though complete remission of clinical signs may not be achieved. This is the first clinical description of COREAH in a dog.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.23.10.0559","type":"journal-article","created":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T16:54:43Z","timestamp":1704473683000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["Dorsal rhinotomy in a dog with a chondro-osseous respiratory epithelial adenomatoid hamartoma: a case report"],"prefix":"10.2460","volume":"262","author":[{"given":"Camille","family":"Andrews","sequence":"first","affiliation":[{"name":"Ryan Veterinary Hospital, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lillian","family":"Aronson","sequence":"additional","affiliation":[{"name":"Ryan Veterinary Hospital, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Molly","family":"Church","sequence":"additional","affiliation":[{"name":"Ryan Veterinary Hospital, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hunter","family":"Piegols","sequence":"additional","affiliation":[{"name":"Ryan Veterinary Hospital, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Veterinary Surgery","first-page":"1919","article-title":"Nasal planum, nasal cavity, and sinuses","author":"Schmiedt CW","year":"2018","unstructured":"Schmiedt CW. Nasal planum, nasal cavity, and sinuses. In: Johnson SA, Tobias KM, eds. Veterinary Surgery. 2nd ed. Elsevier; 2018:1919-1934."},{"issue":"3","key":"ref2","series-title":"Vet Pathol","first-page":"621","article-title":"Nasal cavity masses resembling chondro-osseous respiratory epithelial adenomatoid hamartomas in 3 dogs","volume":"53","author":"LaDouceur EEB","year":"2016","unstructured":"LaDouceur EEB, Michel AO, Lindl Bylicki BJ, Cifuentes FF, Affolter VK, Murphy BG. Nasal cavity masses resembling chondro-osseous respiratory epithelial adenomatoid hamartomas in 3 dogs. Vet Pathol. 2016;53(3):621-624. doi:10.1177\/0300985815598207"},{"issue":"3","key":"ref3","series-title":"Laryngoscope Investig Otolaryngol","first-page":"376","article-title":"Not just another nasal polyp: chondro-osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract","volume":"6","author":"Yu Y","year":"2021","unstructured":"Yu Y, Tan CS, Koh LT. Not just another nasal polyp: chondro-osseous respiratory epithelial adenomatoid hamartomas of the sinonasal tract. Laryngoscope Investig Otolaryngol. 2021;6(3):376-385. doi:10.1002\/lio2.580"},{"issue":"2","key":"ref4","series-title":"J Surg Case Rep","first-page":"rjab007","article-title":"Beware the respiratory epithelial adenomatoid hamartoma-a malignant masquerador","volume":"2021","author":"Kumar SA","year":"2021","unstructured":"Kumar SA, O\u2019Meara C, Fredericks S, Havas T. Beware the respiratory epithelial adenomatoid hamartoma-a malignant masquerador. J Surg Case Rep. 2021;2021(2):rjab007. doi:10.1093\/jscr\/rjab007"},{"issue":"11","key":"ref5","series-title":"J Am Vet Med Assoc","first-page":"1257","article-title":"Lateral rhinotomy and coblation for treatment of a nasal hamartoma in a dog","volume":"256","author":"Prudic RA","year":"2020","unstructured":"Prudic RA, Wallace ML, Bartges JW, McLear PW, Dickerson VM, Perez-Ramirez G. Lateral rhinotomy and coblation for treatment of a nasal hamartoma in a dog. J Am Vet Med Assoc. 2020;256(11):1257-1261. doi:10.2460\/javma.256.11.1257"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/262\/3\/javma.23.10.0559.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/262\/3\/javma.23.10.0559.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/262\/3\/javma.23.10.0559.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:07:01Z","timestamp":1741352821000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/262\/3\/javma.23.10.0559.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,1]]},"references-count":5,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.2460\/javma.23.10.0559","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3,1]]}}}