{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T14:59:38Z","timestamp":1770217178664,"version":"3.49.0"},"reference-count":40,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2007,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To determine whether resistance to oxacillin and other antimicrobials in 3 <jats:italic>Staphylococcus<\/jats:italic> spp commonly isolated from dogs increased from 2001 to 2005.<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\n<jats:p><jats:bold>Sample Population<\/jats:bold>\u20141,772 clinical samples of various types obtained from dogs examined at the University of Tennessee Veterinary Teaching Hospital or at regional veterinary hospitals and submitted to the bacteriology and mycology laboratories associated with the teaching hospital.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Samples were submitted by attending veterinarians to the bacteriology and mycology laboratories for routine aerobic microbial culture. Identification and antimicrobial susceptibility procedures were performed on all isolates. Susceptibility reports for each antimicrobial and <jats:italic>Staphylococcus<\/jats:italic> spp were determined from aggregate electronically archived test results. Oxacillin and multidrug resistance for <jats:italic>Staphylococcus intermedius<\/jats:italic> was analyzed by reviewing disk diffusion zone measurements.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014Oxacillin resistance increased among <jats:italic>S intermedius<\/jats:italic> isolates during the past 5 years, and the increase was associated with multidrug resistance. In 2005, 1 in 5 <jats:italic>Staphylococcus<\/jats:italic> spp isolates from canine clinical samples was resistant to oxacillin. The most common staphylococcal species isolated were <jats:italic>S intermedius<\/jats:italic> (n = 37), <jats:italic>Staphylococcus schleiferi<\/jats:italic> (21), and <jats:italic>Staphylococcus aureus<\/jats:italic> (4), and frequencies of oxacillin resistance in isolates of these species were 15.6%, 46.6%, and 23.5%, respectively.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Veterinarians should be aware of the potential for empiric drug treatment failures in instances where <jats:italic>Staphylococcus<\/jats:italic> spp infections are common (eg, pyoderma). Judicious use of bacterial culture and susceptibility testing is recommended.<\/jats:p>","DOI":"10.2460\/javma.230.2.221","type":"journal-article","created":{"date-parts":[[2007,1,16]],"date-time":"2007-01-16T15:31:26Z","timestamp":1168961486000},"page":"221-227","source":"Crossref","is-referenced-by-count":104,"title":["Prevalence of oxacillin- and multidrug-resistant staphylococci in clinical samples from dogs: 1,772 samples (2001\u20132005)"],"prefix":"10.2460","volume":"230","author":[{"given":"Rebekah D.","family":"Jones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen A.","family":"Kania","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barton W.","family":"Rohrbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda A.","family":"Frank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Bemis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Br J Biomed Sci","first-page":"98","article-title":"Staphylococci in animals: prevalence, identification and antimicrobial susceptibility, with an emphasis on methicillin-resistant Staphylococcus aureus","volume":"62","author":"Rich","year":"2005"},{"key":"ref2","series-title":"Int J Syst Evol Microbiol","first-page":"1569","article-title":"Staphylococcus pseudintermedius sp. nov., a coagulase-positive species from animals","volume":"55","author":"Devriese","year":"2005"},{"key":"ref3","series-title":"Vet Rec","first-page":"600","article-title":"Antimicrobial resistance in staphylococci from canine pyoderma: a prospective study of first-time and recurrent cases in 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