{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T14:25:38Z","timestamp":1774880738957,"version":"3.50.1"},"reference-count":41,"publisher":"American Veterinary Medical Association (AVMA)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2007,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To determine clinical features, outcome, risk factors for death, and efficacy of IV administration of lidocaine as a prophylactic treatment for ischemic reperfusion injury in gastric dilatation and volvulus (GDV) in dogs.<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u2014112 dogs with GDV.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Data pertaining to breed; time lag to admission; clinical, clinicopathologic, and surgical findings; lidocaine treatment; and postoperative complications were assessed for association with outcome.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014German Shepherd Dogs (28.6%) and Great Danes (17%) were significantly over-represented. Risk factors for death included time lag (\u2265 5 hours vs &lt; 5 hours) from onset of clinical signs to admission (46.0% vs 11.3%), rectal temperature (\u2264 38\u00b0C vs &gt; 38\u00b0C [&lt; 100.4\u00b0F vs &gt; 100.4\u00b0F]) at admission (40.0% vs 14.9%), presence or absence of ARF (67.0% vs 23.3%), presence or absence of suspected gastric wall necrosis (59.3% vs 16.0%), and untreated gastric wall necrosis, compared with treated gastric wall necrosis (100% vs 47.6%). Overall mortality rate was 26.8%; no significant differences were detected in mortality rate or postoperative complications between dogs that received lidocaine IV prior to surgical intervention (52.0%) and dogs that did not (48.0%). Mean \u00b1 SD hospitalization time was longer in the lidocaine treatment group (3.5 \u00b1 1.9 days vs 2.5 \u00b1 1.4 days).<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Presence of the identified risk factors should warrant aggressive treatment. Lidocaine treatment was not associated with mortality rate or postoperative complications, but was associated with prolonged hospitalization time.<\/jats:p>","DOI":"10.2460\/javma.230.9.1334","type":"journal-article","created":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T13:28:52Z","timestamp":1178026132000},"page":"1334-1339","source":"Crossref","is-referenced-by-count":41,"title":["Evaluation of lidocaine treatment and risk factors for death associated with gastric dilatation and volvulus in dogs: 112 cases 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