{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T22:35:51Z","timestamp":1778279751420,"version":"3.51.4"},"reference-count":8,"publisher":"American Veterinary Medical Association (AVMA)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2008,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To determine morbidity and fatalities in cats with hepatic lipidosis that received propofol to facilitate placement of a feeding tube.<\/jats:p>\n<jats:p><jats:bold>Study Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u201444 cats with presumed primary hepatic lipidosis anesthetized for placement of a feeding tube.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Medical records from January 1995 through December 2004 were reviewed to identify cats that matched the inclusion criteria (histologic confirmation of hepatic lipidosis, anesthetized for placement of feeding tube, complete intensive care unit [ICU] records, and recorded outcome). Data extracted included age, body weight, sex, anesthetic drugs, drug dosages, type of feeding tube, duration of anesthesia, number of hours in ICU, administration of blood products, and survival until discharge from ICU.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u201444 cats (21 females and 23 males) were included in the analysis. Age range was 3 to 15 years (median, 8 years), and body weight ranged from 1.8 to 9.0 kg (4.0 to 19.8 lb), with a median of 4.8 kg (10.6 lb). Twenty-seven cats were administered propofol. There was no significant association between the use of propofol or the dosage of propofol and any risk factor, need for blood products, number of hours in the ICU, or survival. There was no significant difference between cats that received propofol and cats that did not receive propofol with regard to interval until discharge from the ICU.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014The use of propofol did not increase morbidity or fatalities in cats with primary hepatic lipidosis. Thus, propofol can be used in these cats for placement of a feeding tube.<\/jats:p>","DOI":"10.2460\/javma.232.12.1841","type":"journal-article","created":{"date-parts":[[2008,6,16]],"date-time":"2008-06-16T13:31:06Z","timestamp":1213623066000},"page":"1841-1843","source":"Crossref","is-referenced-by-count":19,"title":["Use of propofol for anesthesia in cats with primary hepatic lipidosis: 44 cases (1995\u20132004)"],"prefix":"10.2460","volume":"232","author":[{"given":"Lysa P.","family":"Posner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Asakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hollis N.","family":"Erb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Pharmacology and physiology in anesthetic practice","first-page":"140","article-title":"Nonbarbiturate induction drugs","author":"Stoelting","year":"1999"},{"key":"ref2","series-title":"Anesthesiology","first-page":"78","article-title":"Pulmonary uptake of propofol in cats. Effect of fentanyl and halothane","volume":"78","author":"Matot","year":"1993"},{"key":"ref3","series-title":"Br J Anaesth","first-page":"177","article-title":"Pharmacokinetics of propofol infusions in patients with cirrhosis","volume":"65","author":"Servin","year":"1990"},{"key":"ref4","series-title":"Vet Surg","first-page":"277","article-title":"The effects of consecutive day propofol anesthesia on feline red blood cells","volume":"24","author":"Andress","year":"1995"},{"key":"ref5","series-title":"Vet Clin North Am Small Anim Pract","first-page":"225","article-title":"Feline hepatic lipidosis","volume":"35","author":"Center","year":"2005"},{"key":"ref6","series-title":"Transplant Proc","first-page":"4567","article-title":"Effect of continuous infusion of propofol on its concentration in blood with and without the liver in pigs","volume":"37","author":"Murayama","year":"2005"},{"key":"ref7","series-title":"Xenobiotica","first-page":"1337","article-title":"Propofol: assay and regional mass balance in the sheep","volume":"19","author":"Mather","year":"1989"},{"key":"ref8","series-title":"J Am Vet Med Assoc","first-page":"231","article-title":"Clinical assessment of repeated propofol-associated anesthesia in cats","volume":"231","author":"Bley","year":"2007"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/232\/12\/javma.232.12.1841.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/232\/12\/javma.232.12.1841.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/232\/12\/javma.232.12.1841.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:27:47Z","timestamp":1741354067000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/232\/12\/javma.232.12.1841.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6,15]]},"references-count":8,"journal-issue":{"issue":"12"},"URL":"https:\/\/doi.org\/10.2460\/javma.232.12.1841","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2008,6,15]]}}}