{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T20:43:07Z","timestamp":1779914587431,"version":"3.53.1"},"reference-count":12,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2008,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To identify radiographic patterns in dogs with pulmonary blastomycosis and radiographic factors associated with outcome.<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u2014125 dogs with pulmonary blastomycosis.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Medical records were reviewed, and for each lung lobe, the primary radiographic pattern and percentage of lobar involvement at the time of initial examination were recorded.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u201479 dogs survived, 38 died, and 8 were euthanized without treatment. The initial radiographic pattern was variable and not significantly associated with outcome. Mean half-time for radiographic resolution of pulmonary infiltrates was 41.4 days for all patterns except masses, for which mean half-time to resolution was 90.8 days. Transient radiographic worsening was seen in 20 of 87 (23%) dogs but was not associated with a poor prognosis. Pulmonary bullae were seen in 20 (16%) dogs, most often in association with an alveolar pattern. Accuracy of using percentage of right caudal lung lobe involvement (\u2264 20% vs &gt; 20%) to predict outcome was 74.4%; accuracy of using number of affected lobes (&lt; 4 vs \u2265 4) to predict outcome was 65.8%.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results suggested that a nonuniform distribution of pulmonary infiltrates was equally as likely as a diffuse nodular interstitial pattern in dogs with pulmonary blastomycosis. On the basis of half-time for resolution of pulmonary infiltrates, follow-up radiography should be performed no more often than every 4 to 6 weeks in clinically stable patients. Transient radiographic worsening that occurred during the initial weeks of treatment was not associated with a poorer prognosis.<\/jats:p>","DOI":"10.2460\/javma.232.2.215","type":"journal-article","created":{"date-parts":[[2008,1,15]],"date-time":"2008-01-15T14:07:35Z","timestamp":1200406055000},"page":"215-221","source":"Crossref","is-referenced-by-count":26,"title":["Radiographic findings in dogs with pulmonary blastomycosis: 125 cases (1989\u20132006)"],"prefix":"10.2460","volume":"232","author":[{"given":"Laura J.","family":"Crews","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel A.","family":"Feeney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl R.","family":"Jessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison B.","family":"Newman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"658","article-title":"Blastomycosis in dogs: 115 cases (1980\u20131995)","volume":"213","author":"Arceneaux","year":"1998"},{"key":"ref2","series-title":"Vet Radiol Ultrasound","first-page":"22","article-title":"Thoracic blastomycosis: a review of its radiographic manifestations in 40 dogs","volume":"22","author":"Walker","year":"1981"},{"key":"ref3","series-title":"J Am Vet Med Assoc","first-page":"1163","article-title":"Canine blastomycosis: a review of 47 clinical cases","volume":"178","author":"Legendre","year":"1981"},{"key":"ref4","series-title":"J Am Vet Med Assoc","first-page":"1249","article-title":"Treatment of canine blastomycosis with amphotericin B and ketoconazole","volume":"184","author":"Legendre","year":"1984"},{"key":"ref5","series-title":"Textbook of respiratory disease in dogs and cats","first-page":"422","article-title":"Aspiration pneumonia","author":"Barton","year":"2004"},{"key":"ref6","series-title":"J Am Vet Radiol Soc","first-page":"67","article-title":"Disseminated pulmonary disease in small animals: a radiographic approach to diagnosis","volume":"9","author":"Suter","year":"1968"},{"key":"ref7","series-title":"Thoracic radiography: a text atlas of thoracic diseases of the dog and cat","first-page":"517","article-title":"Lower airway and pulmonary parenchymal diseases","author":"Suter","year":"1984"},{"key":"ref8","series-title":"Vet Clin North Am Small Anim Pract","first-page":"721","article-title":"Update on canine and feline fungal diseases","volume":"33","author":"Kerl","year":"2003"},{"key":"ref9","series-title":"J Am Vet Med Assoc","first-page":"222","article-title":"Utility of diagnostic tests for and medical treatment of pulmonary blastomycosis in dogs: 125 cases (1989\u20132006)","volume":"232","author":"Crews","year":"2008"},{"key":"ref10","series-title":"J Am Vet Radiol Soc","first-page":"3","article-title":"Radiographic recognition of primary and metastatic pulmonary neoplasms of dogs and cats","volume":"15","author":"Suter","year":"1974"},{"key":"ref11","series-title":"J Vet Intern Med","first-page":"365","article-title":"Treatment of blastomycosis with itraconazole in 112 dogs","volume":"10","author":"Legendre","year":"1996"},{"key":"ref12","series-title":"J Am Vet Radiol Soc","first-page":"134","article-title":"Cavitary pulmonary lesions in animals","volume":"17","author":"Silverman","year":"1976"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/232\/2\/javma.232.2.215.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/232\/2\/javma.232.2.215.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/232\/2\/javma.232.2.215.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:30:33Z","timestamp":1741354233000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/232\/2\/javma.232.2.215.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,15]]},"references-count":12,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.2460\/javma.232.2.215","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1,15]]}}}