{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T14:18:26Z","timestamp":1758637106915,"version":"3.38.0"},"reference-count":25,"publisher":"American Veterinary Medical Association (AVMA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2008,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To measure cardiac output and other hemodynamic variables in anesthetized dogs undergoing laparotomy because of abdominal neoplasia.<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Prospective case series.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u20148 dogs with splenic or hepatic tumors.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Dogs were anesthetized and underwent abdominal laparotomy. End-tidal isoflurane concentration, heart rate, arterial blood pressures, cardiac output, arterial pH, blood gas partial pressures, PCV, and plasma total protein concentration were measured at set intervals before, during, and after surgery. Cardiac index, stroke index, and systemic vascular resistance index were calculated.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014End-tidal isoflurane concentration was lowest before and after surgery. Heart rate did not change significantly throughout the anesthetic period. Arterial blood pressures and systemic vascular resistance index were highest shortly after surgery began; cardiac index and stroke volume index did not change significantly during surgery but increased significantly after surgery ended.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results suggested that in dogs undergoing laparotomy because of abdominal neoplasia, changes in arterial blood pressures were not necessarily indicative of qualitatively similar changes in cardiac index.<\/jats:p>","DOI":"10.2460\/javma.232.4.547","type":"journal-article","created":{"date-parts":[[2008,2,15]],"date-time":"2008-02-15T14:19:45Z","timestamp":1203085185000},"page":"547-552","source":"Crossref","is-referenced-by-count":1,"title":["Cardiac output and other hemodynamic variables in anesthetized dogs undergoing laparotomy because of abdominal neoplasia"],"prefix":"10.2460","volume":"232","author":[{"given":"Ann E.","family":"Wagner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukari","family":"Miyake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Anim Hosp Assoc","first-page":"13","article-title":"Complications and mortality associated with anesthesia in dogs and cats","volume":"35","author":"Gaynor","year":"1999"},{"key":"ref2","series-title":"Vet Med","first-page":"22","article-title":"Anesthesia-related hypotension in a small-animal practice","volume":"101","author":"Gordon","year":"2006"},{"key":"ref3","series-title":"J Am Vet Med Assoc","first-page":"1279","article-title":"Arterial blood pressure monitoring in anesthetized animals","volume":"210","author":"Wagner","year":"1997"},{"key":"ref4","series-title":"Veterinary anaesthesia","first-page":"39","volume":"2001","author":"Hall"},{"key":"ref5","series-title":"Am J Vet Res","first-page":"1463","article-title":"Lee Y-HL, Clarke KW, Alibhai HIK, et al. 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