{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T22:27:04Z","timestamp":1789770424589,"version":"4.0.1"},"reference-count":8,"publisher":"American Veterinary Medical Association (AVMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2008,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Case Description<\/jats:bold>\u2014Two 6-year-old male dogs were evaluated for removal of midline occipito-temporal multilobular osteochondrosarcomas.<\/jats:p>\n<jats:p><jats:bold>Clinical Findings<\/jats:bold>\u2014Physical examination revealed mild ataxia in 1 dog and large masses of the central occipitotemporal portion of the skull in both dogs. Computed tomography, magnetic resonance imaging (MRI), or both revealed large bone-origin occipitotemporal masses with impingement of the brain and the sagittal and transverse venous sinuses. Three-dimensional contrast magnetic resonance image reconstruction delineated collateral venous circulation around the tumor and venous sinus occlusion in 1 dog.<\/jats:p>\n<jats:p><jats:bold>Treatment and Outcome<\/jats:bold>\u2014Tumors in both dogs were surgically removed and the skull defects repaired with polymethyl methacrylate prostheses. Twenty-four hours after surgery, 1 dog had normal mentation, cranial nerve function, and conscious proprioceptive responses, whereas the other dog had depressed mentation but no neurologic deficits. Both dogs were discharged 4 days after surgery with normal mentation and no neurologic deficits.<\/jats:p>\n<jats:p><jats:bold>Clinical Relevance<\/jats:bold>\u2014Findings suggested that MRI and computed tomography can play a key role in assessment of essential cortical collateral circulation when surgical removal of tumors is likely to result in bilateral disruption of transverse venous sinuses. Without robust collateral circulation and proper preoperative planning, removal of massive skull tumors in the midline occipitotemporal region will likely result in substantial morbidity or death. However, results in the 2 dogs reported here indicate the feasibility of removing such tumors with good outcomes in the presence of well-developed collateral venous drainage.<\/jats:p>","DOI":"10.2460\/javma.233.5.752","type":"journal-article","created":{"date-parts":[[2008,9,2]],"date-time":"2008-09-02T12:28:41Z","timestamp":1220358521000},"page":"752-757","source":"Crossref","is-referenced-by-count":16,"title":["Massive midline occipitotemporal resection of the skull for treatment of multilobular osteochondrosarcoma in two dogs"],"prefix":"10.2460","volume":"233","author":[{"given":"Javier","family":"Gallegos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Schwarz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan F.","family":"McAnulty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"67","article-title":"Cranioplasty by means of molded polymethylmethacrylate prosthetic reconstruction after radical excision of neoplasms of the skull in two dogs","volume":"223","author":"Bryant","year":"2003"},{"key":"ref2","series-title":"J Am Anim Hosp Assoc","first-page":"11","article-title":"Multilobular osteochondrosarcoma in 39 dogs: 1979\u20131993","volume":"34","author":"Dernell","year":"1998"},{"key":"ref3","series-title":"J Am Vet Med Assoc","first-page":"1764","article-title":"Multilobular osteochondrosarcoma of the canine skull: 16 cases (1978\u20131988)","volume":"195","author":"Straw","year":"1989"},{"key":"ref4","series-title":"Neurosurgery","first-page":"1263","article-title":"Meningiomas invading the superior sagittal sinus: surgical experience in 108 cases","volume":"55","author":"DiMeco","year":"2004"},{"key":"ref5","series-title":"Neurol India","first-page":"482","article-title":"Experimental study of rapid versus slow sagittal sinus occlusion in dogs","volume":"51","author":"Tuzgen","year":"2003"},{"key":"ref6","series-title":"Miller's anatomy of the dog","first-page":"708","article-title":"Veins","author":"Evans","year":"1993"},{"key":"ref7","series-title":"Vet Radiol Ultrasound","first-page":"214","article-title":"Computed tomographic characteristics of multilobular tumor of bone involving the cranium in 7 dogs and zygomatic arch in 2 dogs","volume":"41","author":"Hathcock","year":"2002"},{"key":"ref8","series-title":"Vet Radiol Ultrasound","first-page":"14","article-title":"Magnetic resonance imaging features of multilobular osteochondrosarcoma in 3 dogs","volume":"42","author":"Lipzitz","year":"2001"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/233\/5\/javma.233.5.752.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/233\/5\/javma.233.5.752.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/233\/5\/javma.233.5.752.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:53:20Z","timestamp":1741355600000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/233\/5\/javma.233.5.752.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,1]]},"references-count":8,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.2460\/javma.233.5.752","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9,1]]}}}