{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:10:25Z","timestamp":1770217825097,"version":"3.49.0"},"reference-count":38,"publisher":"American Veterinary Medical Association (AVMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2008,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To assess the role of <jats:italic>Bartonella<\/jats:italic> spp in chronic rhinosinusitis (CRS) by determining detection rates for the organism by serologic testing and microbial culture of blood samples for <jats:italic>Bartonella<\/jats:italic> spp in cats with CRS and control cats (cats with other nasal diseases, cats with systemic illnesses, and healthy cats).<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Prospective case-control study.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u201419 cats with CRS, 10 cats with other nasal diseases, 15 cats with systemic illness, and 15 healthy cats.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Serologic testing for <jats:italic>Bartonella clarridgeiae<\/jats:italic> and <jats:italic>Bartonella henselae<\/jats:italic> and microbial culture of blood samples were conducted in all cats. In cats with CRS and cats with other nasal diseases, a nasal biopsy specimen was submitted, when available, for tissue PCR assay to detect <jats:italic>Bartonella<\/jats:italic> spp.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u20149 of 19 cats with CRS had positive results for serologic testing for 1 or both <jats:italic>Bartonella<\/jats:italic> spp; whereas, 4 of 10 cats with other nasal diseases, 2 of 15 cats with systemic diseases, and 4 of 15 healthy cats had positive results for serologic testing to detect <jats:italic>Bartonella<\/jats:italic> spp. These values did not differ significantly among groups. Microbial culture of blood samples yielded <jats:italic>B henselae<\/jats:italic> in 1 cat with a nasopharyngeal abscess. The PCR assay for <jats:italic>Bartonella<\/jats:italic> spp in nasal tissues yielded negative results for 9 of 9 cats with CRS and 5 of 5 cats with other nasal diseases.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014A role for <jats:italic>Bartonella<\/jats:italic> spp in the pathogenesis of CRS in cats was not supported by results of this study.<\/jats:p>","DOI":"10.2460\/javma.233.7.1084","type":"journal-article","created":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T12:30:52Z","timestamp":1222864252000},"page":"1084-1089","source":"Crossref","is-referenced-by-count":16,"title":["Microbial culture of blood samples and serologic testing for bartonellosis in cats with chronic rhinosinusitis"],"prefix":"10.2460","volume":"233","author":[{"given":"Nicolas A.","family":"Berryessa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynelle R.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rick W.","family":"Kasten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno B.","family":"Chomel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"395","article-title":"Correlation of rhinoscopic signs of inflammation with histologic findings in nasal biopsy specimens of cats with or without upper respiratory tract disease","volume":"225","author":"Johnson","year":"2004"},{"key":"ref2","series-title":"J Am Vet Med Assoc","first-page":"579","article-title":"Assessment of infectious organisms associated with chronic rhinosinusitis in cats","volume":"227","author":"Johnson","year":"2005"},{"key":"ref3","series-title":"Vet 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