{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:10:09Z","timestamp":1787501409024,"version":"build-2736575974"},"reference-count":49,"publisher":"American Veterinary Medical Association (AVMA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2009,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective<\/jats:bold>\n                    \u2014To identify risk factors potentially associated with the development of bacterial endocarditis in dogs and determine whether periodontal disease and surgical procedures (oral and nonoral) were associated with bacterial endocarditis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design<\/jats:bold>\n                    \u2014Retrospective case-control study.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Animals<\/jats:bold>\n                    \u201476 dogs with (cases) and 80 dogs without (controls) bacterial endocarditis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Procedures<\/jats:bold>\n                    \u2014Medical records were reviewed for information on signalment, physical examination findings, recent medical history, and results of echocardiography, clinicopatho- logic testing, and necropsy.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    \u2014None of the dogs with endocarditis had a history of undergoing any dental or oral procedure in the 3 months prior to the diagnosis of endocarditis, and no significant difference was found between groups with regard to the prevalence of oral infection. Dogs with endocarditis were significantly more likely to have undergone a nonoral surgical procedure that required general anesthesia in the preceding 3 months or to have developed a new heart murmur or a change in intensity of an existing heart murmur. Preexisting cardiac dis-ease (congenital or acquired) was not found to be a risk factor.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\n                    \u2014Results did not provide any evidence of an association between bacterial endocarditis in dogs and either dental or oral surgical procedures or oral infection. Findings suggested that the routine use of prophylactic antimicrobial administration in dogs undergoing oral procedures needs to be reevaluated.\n                  <\/jats:p>","DOI":"10.2460\/javma.234.1.100","type":"journal-article","created":{"date-parts":[[2009,1,2]],"date-time":"2009-01-02T16:46:52Z","timestamp":1230914812000},"page":"100-107","source":"Crossref","is-referenced-by-count":51,"title":["Association of periodontal disease, oral procedures, and other clinical findings with bacterial endocarditis in dogs"],"prefix":"10.2460","volume":"234","author":[{"given":"Gordon D.","family":"Peddle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth J.","family":"Drobatz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin E.","family":"Harvey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meg M.","family":"Sleeper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Dent Clin North Am","first-page":"635","article-title":"Antibiotic prophylaxis for endocarditis, prosthetic joints, and surgery","volume":"46","author":"Seymour","year":"2002"},{"key":"ref2","series-title":"Neth J Med","first-page":"423","article-title":"Prophylaxis of endocarditis","volume":"60","author":"Van der Meer","year":"2002"},{"key":"ref3","series-title":"N Engl J Med","first-page":"38","article-title":"Prevention of infective endocarditis","volume":"332","author":"Durack","year":"1995"},{"key":"ref4","series-title":"Ann Intern Med","first-page":"761","article-title":"Dental and cardiac risk factors for infective endocarditis: a population-based case-control study","volume":"129","author":"Strom","year":"1998"},{"key":"ref5","series-title":"Eur Heart J","first-page":"1968","article-title":"Procedures associated with infective endocarditis in adults. A case control study","volume":"16","author":"Lacassin","year":"1995"},{"key":"ref6","series-title":"JAMA","first-page":"1794","article-title":"Prevention of bacterial endocarditis. Recommendations by the American Heart Association","volume":"277","author":"Dajani","year":"1997"},{"key":"ref7","series-title":"Ann Intern Med","first-page":"829","article-title":"Antibiotics for prevention of endocarditis during dentistry: time to scale back?","volume":"129","author":"Durack","year":"1998"},{"key":"ref8","series-title":"J Am Vet Med Assoc","first-page":"278","article-title":"Acute vegetative endocarditis in the dog and cat","volume":"129","author":"Meier","year":"1956"},{"key":"ref9","series-title":"J Vet Intern Med","first-page":"268","article-title":"Mitral valve endocarditis after dental prophylaxis in a dog","volume":"19","author":"Tou","year":"2005"},{"key":"ref10","series-title":"Vet Surg","first-page":"26","article-title":"Bacterial isolates from plaque and from blood during and after routine dental procedures in dogs","volume":"26","author":"Nieves","year":"1997"},{"key":"ref11","series-title":"Vet Surg","first-page":"27","article-title":"Bacterial isolates from blood cultures of dogs undergoing dentistry","volume":"22","author":"Harari","year":"1993"},{"key":"ref12","series-title":"J Am Anim Hosp Assoc","first-page":"611","article-title":"Bacteremia during ultrasonic teeth cleaning and extraction in the dog","volume":"16","author":"Black","year":"1980"},{"key":"ref13","series-title":"J Am Vet Med Assoc","first-page":"612","article-title":"Cardiovascular infections in dogs: epizootiology, clinical manifestations, and prognosis","volume":"187","author":"Calvert","year":"1985"},{"key":"ref14","series-title":"Vet Med (Praha)","first-page":"483","article-title":"Identifying the cardiovascular and pulmonary diseases that affect old dogs","volume":"85","author":"Hamlin","year":"1990"},{"key":"ref15","series-title":"J Vet Med B Infect Dis Vet Public Health","first-page":"311","article-title":"Taxonomic evidence that serovar 7 of Erysipelothrix strains isolated from dogs with endocarditis are Erysipelothrix tonsillarum","volume":"47","author":"Takahashi","year":"2000"},{"key":"ref16","series-title":"J Vet Dent","first-page":"57","article-title":"Association of periodontal disease and histologic lesions in multiple organs from 45 dogs","volume":"13","author":"DeBowes","year":"1996"},{"key":"ref17","series-title":"Circulation","first-page":"1736","article-title":"Prevention of infective endocarditis: Guidelines from the American Heart Association: Guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group","volume":"116","author":"Wilson","year":"2007"},{"key":"ref18","series-title":"Aust Dent J","first-page":"220","article-title":"Concepts for the prophylaxis of infective endocarditis in dentistry","volume":"46","author":"Titsas","year":"2001"},{"key":"ref19","series-title":"J Am Vet Med Assoc","first-page":"661","article-title":"Requests additional information on infective endocarditis study (lett)","volume":"229","author":"Harvey","year":"2006"},{"key":"ref20","series-title":"J Vet Dent","first-page":"94","article-title":"Association of age and body weight with periodontal disease in North American dogs","volume":"11","author":"Harvey","year":"1994"},{"key":"ref21","series-title":"Infect Dis Clin North Am","first-page":"9","article-title":"Risk factors for infective endocarditis","volume":"7","author":"Steckelberg","year":"1993"},{"key":"ref22","series-title":"J Am Vet Med Assoc","first-page":"570","article-title":"Endocarditis of the aortic valve in the dog","volume":"184","author":"Sisson","year":"1984"},{"key":"ref23","series-title":"J Am Vet Med Assoc","first-page":"1735","article-title":"Clinocopathologic findings and outcome in dogs with infective endocarditis: 71 cases (1992\u20132005)","volume":"228","author":"Sykes","year":"2006"},{"key":"ref24","series-title":"Am J Cardiol","first-page":"746","article-title":"Discrete subaortic stenosis in Newfoundland dogs: association of infective endocarditis","volume":"41","author":"Muna","year":"1978"},{"key":"ref25","series-title":"J Am Vet Med Assoc","first-page":"1723","article-title":"Evaluation of the relationship between causative organisms and clinical characteristics of infective endocarditis in dogs: 71 cases (1992\u20132005)","volume":"228","author":"Sykes","year":"2006"},{"key":"ref26","series-title":"J Am Vet Med Assoc","first-page":"1080","article-title":"Valvular bacterial endocarditis in the dog","volume":"180","author":"Calvert","year":"1982"},{"key":"ref27","series-title":"Compend Contin Educ Pract Vet","first-page":"614","article-title":"Infective endocarditis in dogs","volume":"24","author":"Wall","year":"2002"},{"key":"ref28","series-title":"J Am Anim Hosp Assoc","first-page":"149","article-title":"Vegetative endocarditis in dogs","volume":"20","author":"Anderson","year":"1984"},{"key":"ref29","series-title":"J Small Anim Pract","first-page":"325","article-title":"Vegetative bacterial endocarditis in dogs; echocardiographic diagnosis and clinical signs","volume":"24","author":"Lombard","year":"1983"},{"key":"ref30","series-title":"Vet Pathol","first-page":"370","article-title":"Pathology of Bartonella endocarditis in six dogs","volume":"42","author":"Pesavento","year":"2005"},{"key":"ref31","series-title":"J Am Soc Echocardiogr","first-page":"938.e5","article-title":"Biventricular mural vegetations in a patient without valvular pathology","volume":"19","author":"Ahmed","year":"2006"},{"key":"ref32","series-title":"Ann Intern Med","first-page":"219","article-title":"Nonvalvular infections of the cardiovascular system","volume":"121","author":"Kearney","year":"1994"},{"key":"ref33","series-title":"Arch Pathol","first-page":"435","article-title":"Active endocarditis confined to the mural endocardium: a study of six necropsy patients","volume":"93","author":"Buchbinder","year":"1972"},{"key":"ref34","series-title":"Chest","first-page":"757","article-title":"Left atrial bacterial mural endocarditis","volume":"99","author":"Bierbrier","year":"1991"},{"key":"ref35","series-title":"J Small Anim Pract","first-page":"420","article-title":"Clinical and echocardiographic findings in 10 dogs with vegetative bacterial endocarditis","volume":"34","author":"Elwood","year":"1993"},{"key":"ref36","series-title":"J Vet Cardiol","first-page":"35","article-title":"Pathologic and clinical features of infective endocarditis","volume":"6","author":"Miller","year":"2004"},{"key":"ref37","series-title":"Vet Pathol","first-page":"579","article-title":"Left ventricular outflow tract-right atrial communication (Gerbode type defect) associated with bacterial endocarditis in a dog","volume":"40","author":"Ram\u00edrez","year":"2003"},{"key":"ref38","series-title":"J Vet Intern Med","first-page":"456","article-title":"Thrombotic endocarditis in 10 alpacas","volume":"22","author":"Firshman","year":"2008"},{"key":"ref39","series-title":"J Comp Pathol","first-page":"317","article-title":"Complications of a permanent transvenous pacing catheter in a horse","volume":"101","author":"Hamir","year":"1989"},{"key":"ref40","series-title":"Vet Pathol","first-page":"21","article-title":"Lesions caused by cardiovascular flukes (Digenea: Spirorchidae) in stranded green turtles (Chelonia mydas)","volume":"35","author":"Gordon","year":"1998"},{"key":"ref41","series-title":"Lab Anim Sci","first-page":"85","article-title":"Bacterial endocarditis with obstruction of the right atrioventricular orifice and pulmonary outflow trace in an African monkey (Cercopithecus aethiops)","volume":"28","author":"Wood","year":"1978"},{"key":"ref42","series-title":"Small animal cardiovascular medicine","first-page":"402","article-title":"Infective endocarditis","author":"Kittleson","year":"1998"},{"key":"ref43","series-title":"Heart disease: a textbook of cardiovascular medicine","first-page":"1077","article-title":"Infective endocarditis","author":"Karchmer","year":"2004"},{"key":"ref44","series-title":"J Periodontol","first-page":"841","article-title":"Periodontal disease as a potential risk factor for systemic diseases","volume":"69","author":"Scannapieco","year":"1998"},{"key":"ref45","series-title":"Compend Contin Educ Dent Suppl","first-page":"12","article-title":"Strength of evidence linking oral conditions and systemic disease","volume":"30","author":"Joshipura","year":"2000"},{"key":"ref46","series-title":"Periodontology","first-page":"121","article-title":"How periodontal disease may contribute to cardiovascular disease","volume":"23","author":"Kinane","year":"2000"},{"key":"ref47","series-title":"Periodontology","first-page":"21","article-title":"Relationship between periodontal disease and systemic health","volume":"25","author":"Garcia","year":"2000"},{"key":"ref48","series-title":"Periodontology","first-page":"110","article-title":"Oral disease, cardiovascular disease and systemic inflammation","volume":"23","author":"Beck","year":"2000"},{"key":"ref49","series-title":"Periodontology","first-page":"13","article-title":"A history of oral sepsis as a cause of disease","volume":"23","author":"O'Reilly","year":"2000"}],"container-title":["Journal of the American Veterinary Medical 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