{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:13:17Z","timestamp":1770217997549,"version":"3.49.0"},"reference-count":18,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2009,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Case Description<\/jats:bold>\u2014A 2-year-old spayed female domestic shorthair cat was examined because of bilateral thoracic limb weakness of acute onset.<\/jats:p>\n<jats:p><jats:bold>Clinical Findings<\/jats:bold>\u2014Clinical signs included muscle atrophy, paresis, depressed spinal reflexes, hyperesthesia of the thoracic limbs, and reduced jaw muscle tone. Pelvic limb reflexes were normal. Results of a neurologic examination were suggestive of multifocal lesions involving both brachial plexuses and the trigeminal nerves. Abnormal nerve conduction across the brachial plexus and delayed late potentials were found on electrodiagnostic testing, and diffuse subclinical involvement of other regions of the peripheral nervous system was confirmed on the basis of abnormal electromyographic findings for the masticatory muscles and conduction block of the peroneal nerve.<\/jats:p>\n<jats:p><jats:bold>Treatment and Outcome<\/jats:bold>\u2014No specific treatments were given, and neurologic signs resolved within a month. A relapse occurred 2 months after the first episode, with clinical signs affecting both the pelvic and the thoracic limbs on this occasion. Again, the condition resolved without specific treatment, and 13 months after the initial episode, the cat reportedly was normal.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Findings suggested that brachial plexus neuropathy can be a multifocal disease in cats, even if clinically apparent neurologic deficits are initially subtle or absent, and that electrodiagnostic techniques can be used to identify subclinical involvement of the peripheral nerves.<\/jats:p>","DOI":"10.2460\/javma.234.2.240","type":"journal-article","created":{"date-parts":[[2009,1,15]],"date-time":"2009-01-15T12:29:02Z","timestamp":1232022542000},"page":"240-244","source":"Crossref","is-referenced-by-count":8,"title":["Electrophysiologic evidence of polyneuropathy in a cat with signs of bilateral brachial plexus neuropathy"],"prefix":"10.2460","volume":"234","author":[{"given":"Paul M.","family":"Freeman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas R.","family":"Harcourt-Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick D.","family":"Jeffery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Granger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Fundamentals of veterinary clinical neurology","first-page":"57","article-title":"Chapter 3: clinical examination of the animal with suspected neurological disease","author":"Bagley","year":"2005"},{"key":"ref2","series-title":"Electrodiagnosis in diseases of nerve and muscle: principles and practice","author":"Kimura","year":"2001"},{"key":"ref3","series-title":"Am J Vet Res","first-page":"1433","article-title":"Motor nerve conduction velocity and latency in the dog","volume":"40","author":"Walker","year":"1979"},{"key":"ref4","series-title":"Am J Vet Res","first-page":"1042","article-title":"Sensory nerve conduction velocity of cutaneous afferents of the radial, ulnar, peroneal, and tibial nerves of the cat: reference values","volume":"45","author":"Redding","year":"1984"},{"key":"ref5","series-title":"J Small Anim Pract","first-page":"396","article-title":"Motor nerve conduction parameters in the cat","volume":"30","author":"Malik","year":"1989"},{"key":"ref6","series-title":"Prog Vet Neurol","first-page":"95","article-title":"Age-related changes in peripheral nerve conduction velocities of cats","volume":"2","author":"Pillai","year":"1991"},{"key":"ref7","series-title":"Am J Vet Res","first-page":"977","article-title":"Characteristics of F and H waves of ulnar and tibial nerves in cats: reference values","volume":"46","author":"Knecht","year":"1985"},{"key":"ref8","series-title":"J Am Anim Hosp Assoc","first-page":"612","article-title":"Brachial plexus neuropathy in the cat: a case report","volume":"14","author":"Bright","year":"1978"},{"key":"ref9","series-title":"J Feline Med Surg","first-page":"63","article-title":"Bilateral, hypertrophic neuritis of the brachial plexus in a cat: magnetic resonance imaging and pathological findings","volume":"8","author":"Garosi","year":"2006"},{"key":"ref10","series-title":"Cornell Vet","first-page":"589","article-title":"Canine brachial plexus neuritis: a syndrome resembling serum neuritis in man","volume":"63","author":"Cummings","year":"1973"},{"key":"ref11","series-title":"J Am Anim Hosp Assoc","first-page":"515","article-title":"A, Scott DW. A case of brachial plexus neuropathy in a dog","volume":"10","author":"de","year":"1974"},{"key":"ref12","series-title":"Vet Q","first-page":"63","article-title":"Acute idiopathic polyneuropathy in nine cats","volume":"18","author":"Gerritsen","year":"1996"},{"key":"ref13","series-title":"Muscle Nerve","first-page":"559","article-title":"Conduction block in neuralgic amyotrophy","volume":"24","author":"Watson","year":"2001"},{"key":"ref14","series-title":"Lancet","first-page":"973","article-title":"Neuralgic amyotrophy. The shoulder-girdle syndrome","volume":"1","author":"Parsonage","year":"1948"},{"key":"ref15","series-title":"Neurology","first-page":"559","article-title":"Immune brachial plexus neuropathy: suggestive evidence for an inflammatory-immune pathogenesis","volume":"46","author":"Suarez","year":"1996"},{"key":"ref16","series-title":"Acta Neurol Scand","first-page":"183","article-title":"Blood lymphocytes are sensitized to branchial plexus nerves in patients with neuralgic amyotrophy","volume":"83","author":"Sierra","year":"1991"},{"key":"ref17","series-title":"Arch Neurol","first-page":"1301","article-title":"Anti-peripheral nerve myelin antibodies and terminal activation products of complement in serum of patients with acute brachial plexus neuropathy","volume":"50","author":"Vriesendorp","year":"1993"},{"key":"ref18","series-title":"Muscle Nerve","first-page":"435","article-title":"The variations of neuralgic amyotrophy","volume":"22","author":"England","year":"1999"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/234\/2\/javma.234.2.240.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/234\/2\/javma.234.2.240.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/234\/2\/javma.234.2.240.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:26:57Z","timestamp":1741354017000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/234\/2\/javma.234.2.240.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,15]]},"references-count":18,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.2460\/javma.234.2.240","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1,15]]}}}