{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T06:27:26Z","timestamp":1784356046296,"version":"3.55.0"},"reference-count":45,"publisher":"American Veterinary Medical Association (AVMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2009,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To determine incidence of and risk factors for postoperative pneumonia in dogs anesthetized for diagnosis or treatment of intervertebral disk disease (IVDD).<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Retrospective case-control study.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u2014707 dogs that underwent general anesthesia for the diagnosis or treatment of IVDD between 1992 and 1996 or between 2002 and 2006.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Postoperative pneumonia was diagnosed if compatible clinical signs (cough or hypoxemia) and radiographic abnormalities (alveolar infiltrates) developed within 48 hours after anesthesia. To identify risk factors for postoperative pneumonia, findings for dogs that developed postoperative pneumonia between 2002 and 2006 were compared with findings for a randomly selected control group of unaffected dogs from the same population.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014There were no significant differences in age, breed, body weight, sex, location of IVDD, or survival rate between the 2 time periods, but there were significant differences in the use of magnetic resonance imaging, computed tomography, and hemilaminectomy and in the percentage of dogs that developed postoperative pneumonia in the later (4.6%) versus the earlier (0.6%) years. Significant risk factors for postoperative pneumonia included preanesthetic tetraparesis, cervical lesions, undergoing magnetic resonance imaging, undergoing &gt; 1 anesthetic procedure, longer duration of anesthesia, and postanesthetic vomiting or regurgitation.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Results suggested that at this institution, the incidence of postoperative pneumonia in dogs anesthetized for diagnosis or treatment of IVDD had increased in recent years.<\/jats:p>","DOI":"10.2460\/javma.235.3.281","type":"journal-article","created":{"date-parts":[[2009,8,3]],"date-time":"2009-08-03T13:43:26Z","timestamp":1249307006000},"page":"281-287","source":"Crossref","is-referenced-by-count":43,"title":["Incidence of and risk factors for postoperative pneumonia in dogs anesthetized for diagnosis or treatment of intervertebral disk disease"],"prefix":"10.2460","volume":"235","author":[{"given":"Melissa A.","family":"Java","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth J.","family":"Drobatz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert S.","family":"Gilley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel N.","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynne I.","family":"Kushner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesley G.","family":"King","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Vet Comp Orthop Traumatol","first-page":"29","article-title":"Outcome and prognostic factors in non-ambulatory Hansen Type I intervertebral disc extrusions: 308 cases","volume":"19","author":"Ruddle","year":"2006"},{"key":"ref2","series-title":"Surg Neurol","first-page":"609","article-title":"Review: complications of surgery for thoracic disc disease","volume":"49","author":"Fessler","year":"1998"},{"key":"ref3","series-title":"J Am Anim Hosp Assoc","first-page":"665","article-title":"Thoracolumbar disk disease in the dog: a retrospective analysis of 187 cases","volume":"13","author":"Brown","year":"1977"},{"key":"ref4","series-title":"J Am Anim Hosp Assoc","first-page":"739","article-title":"An analysis of intraoperative and early postoperative mortality associated with cervical spinal decompressive surgery in the dog","volume":"22","author":"Clark","year":"1986"},{"key":"ref5","series-title":"J Am Vet Med Assoc","first-page":"1598","article-title":"Ventilatory failure, ventilator management, and outcome in dogs with cervical spinal disorders: 14 cases (1991\u20131999)","volume":"218","author":"Beal","year":"2001"},{"key":"ref6","series-title":"Spine","first-page":"1441","article-title":"Prospective analysis of incidence and risk factors of dysphagia in spine surgery patients","volume":"29","author":"Smith-Hammond","year":"2004"},{"key":"ref7","series-title":"J Vet Emerg Crit Care","first-page":"184","article-title":"Postoperative pulmonary complications in dogs undergoing laparotomy: anesthetic and perioperative factors","volume":"16","author":"Brainard","year":"2006"},{"key":"ref8","series-title":"J Vet Emerg Crit Care","first-page":"176","article-title":"Postoperative pulmonary complications in dogs undergoing laparotomy: frequency, characterization and disease-related risk factors","volume":"16","author":"Alwood","year":"2006"},{"key":"ref9","series-title":"Br J Anaesth","first-page":"453","article-title":"Pulmonary aspiration of gastric contents in anaesthesia","volume":"83","author":"Engelhardt","year":"1999"},{"key":"ref10","series-title":"Crit Care Med","first-page":"1930","article-title":"Epidemiology and impact of aspiration pneumonia in patients undergoing surgery in Maryland, 1999\u20132000","volume":"31","author":"Kozlow","year":"2003"},{"key":"ref11","series-title":"Textbook of respiratory disease in dogs and cats","first-page":"422","article-title":"Aspiration pneumonia","author":"Barton","year":"2004"},{"key":"ref12","series-title":"Ann Intern Med","first-page":"593","article-title":"Adult respiratory distress syndrome: risk with common predispositions","volume":"98","author":"Fowler","year":"1983"},{"key":"ref13","series-title":"Ann Intern Med","first-page":"847","article-title":"Development and validation of a multifactorial risk index for predicting post-operative pneumonia after major noncardiac surgery","volume":"135","author":"Arozullah","year":"2001"},{"key":"ref14","series-title":"Lancet","first-page":"1851","article-title":"Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomized trial","volume":"354","author":"Drakulovic","year":"1999"},{"key":"ref15","series-title":"Anesth Analg","first-page":"276","article-title":"Factors associated with postoperative pulmonary complications in patients with severe chronic obstructive pulmonary disease","volume":"80","author":"Wong","year":"1995"},{"key":"ref16","series-title":"J Clin Gastroenterol","first-page":"10","article-title":"Acid suppression in the perioperative period","volume":"39","author":"Pisegna","year":"2005"},{"key":"ref17","series-title":"J Am Geriatr Soc","first-page":"1018","article-title":"Interventions to prevent aspiration pneumonia in older adults: a systematic review","volume":"51","author":"Loeb","year":"2003"},{"key":"ref18","series-title":"AORN J","first-page":"908","article-title":"Using a monitored sip test to assess risk of aspiration in postoperative patients","volume":"83","author":"Osborne","year":"2006"},{"key":"ref19","series-title":"Vet Surg","first-page":"432","article-title":"Pneumonia after intracranial surgery in dogs","volume":"30","author":"Fransson","year":"2001"},{"key":"ref20","series-title":"J Am Vet Med Assoc","first-page":"1949","article-title":"Outcome of and postoperative complications in dogs undergoing surgical treatment of laryngeal paralysis: 140 cases (1985\u20131998)","volume":"218","author":"MacPhail","year":"2001"},{"key":"ref21","series-title":"J Am Anim Hosp Assoc","first-page":"455","article-title":"Postanesthetic esophageal dysfunction in 13 dogs","volume":"40","author":"Wilson","year":"2004"},{"key":"ref22","series-title":"Med Sci Sports Exerc","first-page":"236","article-title":"Diagnosis and treatment of cervical radiculopathy","volume":"29","author":"Malanga","year":"1997"},{"key":"ref23","series-title":"Neurosurgery","first-page":"143S","article-title":"Multiple level discectomy and fusion","volume":"60","author":"Stewart","year":"2007"},{"key":"ref24","series-title":"Vet Radiol Ultrasound","first-page":"20","article-title":"Magnetic resonance imaging features of cervical stenotic myelopathy in 21 dogs","volume":"42","author":"Lipsitz","year":"2001"},{"key":"ref25","series-title":"Br J Anaesth","first-page":"61","article-title":"New concepts of atelectasis during general anesthesia","volume":"91","author":"Magnusson","year":"2003"},{"key":"ref26","series-title":"Acta Anaesthesiol Scand","first-page":"546","article-title":"Atelectasis, gas exchange and lung function in the postoperative period","volume":"36","author":"Lindberg","year":"1992"},{"key":"ref27","series-title":"Electomedica","first-page":"70","article-title":"Atelectasis and gas exchange during anesthesia","volume":"71","author":"Hedenstierna","year":"2003"},{"key":"ref28","series-title":"Anesthesiology","first-page":"456","article-title":"Halothane inhibits the microbicidal oxidative activity of pulmonary alveolar macrophages","volume":"58","author":"Welch","year":"1983"},{"key":"ref29","series-title":"Chest","first-page":"242","article-title":"Impairment of pulmonary antibacterial defense mechanisms are depressed by halothane anesthesia","volume":"75","author":"Manawadu","year":"1979"},{"key":"ref30","series-title":"Anesth Analg","first-page":"1255","article-title":"Loss of alveolar macrophages during anesthesia and operation in humans","volume":"81","author":"Kotani","year":"1995"},{"key":"ref31","series-title":"Am J Surg","first-page":"752","article-title":"Postoperative day one: a high risk period for respiratory events","volume":"190","author":"Taylor","year":"2005"},{"key":"ref32","series-title":"Anesth Analg","first-page":"494","article-title":"Gastroesophageal reflux and aspiration of gastric contents in anesthetic practice","volume":"93","author":"Ng","year":"2001"},{"key":"ref33","series-title":"Vet Anaesth Analg","first-page":"15","article-title":"Pre-anesthetic meperidine:associated vomiting and gastroesophageal reflux during the subsequent anesthetic in dogs","volume":"34","author":"Wilson","year":"2007"},{"key":"ref34","series-title":"Am J Vet Res","first-page":"386","article-title":"Effects of preanesthetic administration of morphine on gastroesophageal reflux and regurgitation during anesthesia in dogs","volume":"66","author":"Wilson","year":"2005"},{"key":"ref35","series-title":"Chest","first-page":"1073","article-title":"Bronchial hyperresponsiveness after cervical spinal injury","volume":"105","author":"Dicpinigaitis","year":"1994"},{"key":"ref36","series-title":"Spinal Cord","first-page":"604","article-title":"Causes of death after spinal cord injury","volume":"38","author":"Soden","year":"2000"},{"key":"ref37","series-title":"Arch Phys Med Rehabil","first-page":"1402","article-title":"Long-term medical complications after traumatic spinal cord injury: a regional model systems analysis","volume":"80","author":"McKinley","year":"1999"},{"key":"ref38","series-title":"Arch Phys Med Rehabil","first-page":"1757","article-title":"Etiology and incidence of rehospitalization after traumatic spinal cord injury: a multicenter analysis","volume":"85","author":"Cardenas","year":"2004"},{"key":"ref39","series-title":"Arch Phys Med Rehabil","first-page":"1101","article-title":"Predictors of dysphagia after spinal cord injury","volume":"80","author":"Kirshblum","year":"1999"},{"key":"ref40","series-title":"J Trauma","first-page":"905","article-title":"Esophageal dysfunction in cervical spinal cord injury: a potentially important mechanism of aspiration","volume":"59","author":"Neville","year":"2005"},{"key":"ref41","series-title":"Vet Rec","first-page":"479","article-title":"Gastroesophageal reflux during anesthesia in the dog: the effect of preoperative fasting and premedication","volume":"137","author":"Galatos","year":"1995"},{"key":"ref42","series-title":"Vet Rec","first-page":"513","article-title":"Gastroesophageal reflux during anesthesia in the dog: the effect of age, positioning and type of surgical procedure","volume":"137","author":"Galatos","year":"1995"},{"key":"ref43","series-title":"Am J Vet Res","first-page":"266","article-title":"Spinal decompressive procedures and dorsal compartment injuries: comparative biomechanical study in canine cadavers","volume":"49","author":"Smith","year":"1988"},{"key":"ref44","series-title":"Vet Rec","first-page":"296","article-title":"A comparison of hemilaminectomy (with concomitant disc fenestration) and dorsal laminectomy for the treatment of thoracolumbar disc protrusion in dogs","volume":"130","author":"McKee","year":"1992"},{"key":"ref45","series-title":"Vet Clin North Am Small Anim Pract","first-page":"859","article-title":"Spinal trauma. 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