{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:54:00Z","timestamp":1787025240846,"version":"build-2736575974"},"reference-count":20,"publisher":"American Veterinary Medical Association (AVMA)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2010,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Case Description<\/jats:bold>\n                    \u2014A 2-month-old female Nigerian Dwarf goat was evaluated for a generalized crusting dermatitis; signs of depression; and fever of 1 month's duration.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Clinical Findings<\/jats:bold>\n                    \u2014Histologic evaluation of skin biopsy specimens revealed subcorneal pustules and rafts of acantholytic cells. No etiologic agents were detected in the biopsy material, and bacterial culture of skin biopsy specimens yielded no growth of pathological organisms. A diagnosis of pemphigus foliaceus was made.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Treatment and Outcome<\/jats:bold>\n                    \u2014Remission was achieved with a combination of SC administration of dexamethasone and IM administration of gold sodium thiomalate. The goat remained free of clinical signs for at least 26 months after discontinuation of all medications. No clinically apparent adverse effects of treatment were evident.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Clinical Relevance<\/jats:bold>\n                    \u2014This report represents the first description of successful treatment of juvenile pemphigus foliaceus in a goat by use of a novel protocol involving dexamethasone and gold sodium thiomalate.\n                  <\/jats:p>","DOI":"10.2460\/javma.236.6.674","type":"journal-article","created":{"date-parts":[[2010,3,15]],"date-time":"2010-03-15T03:03:02Z","timestamp":1268622182000},"page":"674-676","source":"Crossref","is-referenced-by-count":10,"title":["Successful treatment of juvenile pemphigus foliaceus in a Nigerian Dwarf goat"],"prefix":"10.2460","volume":"236","author":[{"given":"Jennifer","family":"Cornish","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Highland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Clin Dermatol","first-page":"393","article-title":"Drug-induced pemphigus","volume":"16","author":"Brenner","year":"1998"},{"key":"ref2","series-title":"J Am Acad Dermatol","first-page":"261","article-title":"Quality of life assessment in patients with pemphigus using a minimum set of evaluation tools","volume":"60","author":"Paradisi","year":"2009"},{"key":"ref3","series-title":"Advances in veterinary dermatology","first-page":"321","article-title":"Autoimmune diseases of domestic animals: an update","author":"Suter","year":"1998"},{"key":"ref4","series-title":"Large animal internal medicine","first-page":"1200","article-title":"Diseases of the skin","author":"White","year":"2002"},{"key":"ref5","series-title":"Indian J Dermatol Venereol Leprol","first-page":"654","article-title":"Complete recovery from juvenile pemphigus vulgaris","volume":"74","author":"El Fekih","year":"2008"},{"key":"ref6","series-title":"Int J Dermatol","first-page":"343","article-title":"Pemphigus in children","volume":"30","author":"Kanwar","year":"1991"},{"key":"ref7","series-title":"Acta Paediatr Scand","first-page":"262","volume":"80","author":"Graff-Lonnevig","year":"1991"},{"key":"ref8","series-title":"Equine internal medicine","first-page":"687","article-title":"Disorders of the skin","author":"Rees","year":"1998"},{"key":"ref9","series-title":"J Am Anim Hosp Assoc","first-page":"189","article-title":"Pemphigus foliaceus in 91 dogs","volume":"42","author":"Meuller","year":"2006"},{"key":"ref10","series-title":"Vet Dermatol","first-page":"245","article-title":"Prolonged remission after immunosuppressive therapy in six dogs with pemphigus foliaceus","volume":"15","author":"Olivry","year":"2004"},{"key":"ref11","series-title":"Vet Dermatol","first-page":"381","article-title":"Pemphigus foliaceus in the horse: a retrospective study of 20 cases","volume":"15","author":"Vandenabeele","year":"2004"},{"key":"ref12","series-title":"Vet Dermatol","first-page":"313","article-title":"Feline pemphigus foliaceus: a retrospective analysis of 57 cases","volume":"14","author":"Preziosi","year":"2003"},{"key":"ref13","series-title":"Agri-Practice","first-page":"38","article-title":"Pemphigus foliaceus in a goat","volume":"5","author":"Scott","year":"1984"},{"key":"ref14","series-title":"Vet Rec","first-page":"479","article-title":"Pemphigus foliaceus in a goat","volume":"114","author":"Jackson","year":"1984"},{"key":"ref15","series-title":"J Am Vet Med Assoc","first-page":"761","article-title":"Use of corticosteroids and aurothioglucose in a pygmy goat with pemphigus foliaceus","volume":"207","author":"Valdez","year":"1995"},{"key":"ref16","series-title":"Vet Dermatol","first-page":"331","article-title":"Pemphigus foliaceus in a goat","volume":"13","author":"Pappalardo","year":"2002"},{"key":"ref17","series-title":"Cochrane Database Syst Rev","article-title":"Interventions for pemphigus vulgaris and pemphigus foliaceus","volume":"3","author":"Martin","year":"2009"},{"key":"ref18","series-title":"Br J Dermatol","first-page":"431","article-title":"Endemic pemphigus foliaceus in western Parana, Brazil (1976\u20131988)","volume":"123","author":"Empinotti","year":"1990"},{"key":"ref19","series-title":"Vet Q","first-page":"123","article-title":"A retrospective evaluation of adverse reactions to trimethoprim-sulphonamide combinations in dogs and cats","volume":"17","author":"Noli","year":"1995"},{"key":"ref20","series-title":"Vet Dermatol","first-page":"195","article-title":"Putative drug-related pemphigus foliaceus in four dogs","volume":"13","author":"White","year":"2002"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/236\/6\/javma.236.6.674.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/236\/6\/javma.236.6.674.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/236\/6\/javma.236.6.674.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T08:21:29Z","timestamp":1741335689000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/236\/6\/javma.236.6.674.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,15]]},"references-count":20,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.2460\/javma.236.6.674","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3,15]]}}}