{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T03:52:44Z","timestamp":1780717964672,"version":"3.54.1"},"reference-count":32,"publisher":"American Veterinary Medical Association (AVMA)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2010,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To determine whether postexposure rabies prophylaxis (PEP) in domestic animals, as mandated in Texas, has continued to be effective and to evaluate preexposure or postexposure vaccination failures from 2000 through 2009.<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Retrospective case series.<\/jats:p>\n<jats:p><jats:bold>Animals<\/jats:bold>\u20141,014 unvaccinated domestic animals (769 dogs, 126 cats, 72 horses, 39 cattle, 3 sheep, 4 goats, and 1 llama) that received PEP and 12 vaccinated domestic animals (7 dogs and 5 cats) with possible failure of protection.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014Zoonotic incident reports from 2000 through 2009 were reviewed for information regarding unvaccinated domestic animals that received PEP in accordance with the state protocol after exposure to a laboratory-confirmed rabid animal; reports also were reviewed for any preexposure or postexposure vaccination failures. The state-required PEP protocol was as follows: immediately vaccinate the animal against rabies, isolate the animal for 90 days, and administer booster vaccinations during the third and eighth weeks of the isolation period.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014From 2000 through 2009, 1,014 animals received PEP; no failures were recorded. One preexposure vaccination failure was recorded.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014The Texas PEP protocol was used during the 10-year period. Results indicated that an effective PEP protocol for unvaccinated domestic animals exposed to rabies was immediate vaccination against rabies, a strict isolation period of 90 days, and administration of booster vaccinations during the third and eighth weeks of the isolation period.<\/jats:p>","DOI":"10.2460\/javma.237.12.1395","type":"journal-article","created":{"date-parts":[[2010,12,15]],"date-time":"2010-12-15T08:02:34Z","timestamp":1292400154000},"page":"1395-1401","source":"Crossref","is-referenced-by-count":23,"title":["Evaluation of a postexposure rabies prophylaxis protocol for domestic animals in Texas: 2000\u20132009"],"prefix":"10.2460","volume":"237","author":[{"given":"Pamela J.","family":"Wilson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest H.","family":"Oertli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick R.","family":"Hunt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Sidwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"1827","article-title":"Postexposure rabies prophylaxis and preexposure rabies vaccination failure in domestic animals","volume":"208","author":"Clark","year":"1996"},{"key":"ref2","series-title":"J Am Vet Med Assoc","first-page":"522","article-title":"Postexposure rabies prophylaxis protocol for domestic animals and epidemiologic characteristics of rabies vaccination failures in Texas: 1995\u20131999","volume":"218","author":"Wilson","year":"2001"},{"issue":"RR-2","key":"ref3","series-title":"MMWR Recomm Rep","first-page":"1","volume":"57","year":"2008"},{"key":"ref4","series-title":"Texas administrative code","article-title":"Title 25, health services. 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Chapter 599, zoonotic disease control","year":"2000"},{"key":"ref32","series-title":"Am J Vet Res","first-page":"1096","article-title":"Postexposure prophylaxis for prevention of rabies in dogs","volume":"63","author":"Hanlon","year":"2002"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/237\/12\/javma.237.12.1395.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/237\/12\/javma.237.12.1395.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/237\/12\/javma.237.12.1395.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T14:02:24Z","timestamp":1741356144000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/237\/12\/javma.237.12.1395.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,15]]},"references-count":32,"journal-issue":{"issue":"12"},"URL":"https:\/\/doi.org\/10.2460\/javma.237.12.1395","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2010,12,15]]}}}