{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:43:45Z","timestamp":1791251025142,"version":"4.1.0"},"reference-count":24,"publisher":"American Veterinary Medical Association (AVMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2011,1,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Objective<\/jats:bold>\u2014To assess patterns of seroreactivity to <jats:italic>Leptospira<\/jats:italic> serovars in veterinary professional staff and dog owners exposed to dogs with acute leptospirosis and to contrast these patterns in people with those observed in dogs.<\/jats:p>\n<jats:p><jats:bold>Design<\/jats:bold>\u2014Cross-sectional study.<\/jats:p>\n<jats:p><jats:bold>Sample Population<\/jats:bold>\u2014Human subjects consisted of 91 people (50 veterinarians, 19 technical staff, 9 administrative personnel, and 13 dog owners) exposed to dogs with leptospirosis. Canine subjects consisted of 52 dogs with naturally occurring leptospirosis admitted to the University of Bern Vetsuisse Faculty Small Animal Clinic in 2007 and 2008.<\/jats:p>\n<jats:p><jats:bold>Procedures<\/jats:bold>\u2014People were tested for seroreactivity to regionally prevalent <jats:italic>Leptospira<\/jats:italic> serovars by use of a complement fixation test. A questionnaire designed to identify risk factors associated with seropositivity was used to collect demographic information from each study participant. Dogs were tested for seroreactivity to <jats:italic>Leptospira<\/jats:italic> serovars by use of a microscopic agglutination test.<\/jats:p>\n<jats:p><jats:bold>Results<\/jats:bold>\u2014On the basis of microscopic agglutination test results, infected dogs were seropositive for antibodies against <jats:italic>Leptospira<\/jats:italic> serovars as follows (in descending order): Bratislava (43\/52 [83%]), Australis (43\/52 [83%]), Grippotyphosa (18\/52 [35%]), Pomona (12\/52 [23%]), Autumnalis (6\/52 [12%]), Icterohemorrhagiae (4\/52 [8%]), Tarassovi (2\/52 [4%]), and Canicola (1\/52 [2%]). All 91 people were seronegative for antibodies against <jats:italic>Leptospira<\/jats:italic> serovars. Therefore, statistical evaluation of risk factors and comparison of patterns of seroreactivity to <jats:italic>Leptospira<\/jats:italic> serovars between human and canine subjects were limited to theoretical risks.<\/jats:p>\n<jats:p><jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\u2014Seroreactivity to <jats:italic>Leptospira<\/jats:italic> serovars among veterinary staff adhering to standard hygiene protocols and pet owners exposed to dogs with acute leptospirosis was uncommon.<\/jats:p>","DOI":"10.2460\/javma.238.2.183","type":"journal-article","created":{"date-parts":[[2011,1,15]],"date-time":"2011-01-15T08:02:38Z","timestamp":1295078558000},"page":"183-188","source":"Crossref","is-referenced-by-count":27,"title":["Assessment of exposure to Leptospira serovars in veterinary staff and dog owners in contact with infected dogs"],"prefix":"10.2460","volume":"238","author":[{"given":"Reto","family":"Barmettler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariane","family":"Schweighauser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Bigler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy M.","family":"Grooters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Francey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Rev Prat","first-page":"665","article-title":"Leptospirosis [in French]","volume":"59","author":"Abgueguen","year":"2009"},{"key":"ref2","series-title":"Lancet Infect Dis","first-page":"757","article-title":"Leptospirosis: a zoonotic 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in leptospirosis epidemiology in France. Sixty-six years of passive serological surveillance from 1920 to 2003","volume":"10","author":"Baranton","year":"2006"},{"key":"ref22","series-title":"Analysis of the 1998 outbreak of leptospirosis in Missouri in humans exposed to infected swine","first-page":"676","volume":"216","author":"Campagnolo","year":"2000"},{"key":"ref23","series-title":"J Postgrad Med","first-page":"174","article-title":"A global research agenda for leptospirosis","volume":"51","author":"Cachay","year":"2005"},{"key":"ref24","series-title":"J Am Vet Med Assoc","first-page":"938","article-title":"Prevalence of and risk factors for serum antibodies against Leptospira serovars in US veterinarians","volume":"234","author":"Whitney","year":"2009"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/238\/2\/javma.238.2.183.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/238\/2\/javma.238.2.183.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/238\/2\/javma.238.2.183.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T14:03:28Z","timestamp":1741356208000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/238\/2\/javma.238.2.183.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,15]]},"references-count":24,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.2460\/javma.238.2.183","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1,15]]}}}