{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:25:31Z","timestamp":1787930731511,"version":"build-2784847793"},"reference-count":33,"publisher":"American Veterinary Medical Association (AVMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2011,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective<\/jats:bold>\n                    \u2014To evaluate the outcome and describe the complications associated with use of an Ahmed gonioimplant in the treatment of glaucoma in dogs.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design<\/jats:bold>\n                    \u2014Retrospective case series.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Animals\u2014<\/jats:bold>\n                    9 client-owned sighted dogs (median age, 9 years) with primary glaucoma.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Procedures<\/jats:bold>\n                    \u2014Medical records of dogs with primary glaucoma that underwent unilateral gonioimplant placement (in 2000 through 2008), during which a temporalis muscle fascia graft (n = 8) or porcine intestinal submucosa (1) was used to cover the implant tube as it exited the globe, were reviewed. All dogs were treated with mitomycin C in the conjunctival pocket intraoperatively and with tissue plasminogen activator immediately after surgery; 1% prednisolone acetate was applied to the implanted eye daily until failure of the implant. Medical intervention or additional surgery was performed when intraocular pressures (IOPs) were &gt; 20 mm Hg or progressively increasing values were detected.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    \u2014After gonioimplant placement, IOP was controlled for a variable period in all dogs. Subsequently, IOP exceeded 20 mm Hg in 7 dogs (median postoperative interval, 326 days). Median interval to vision loss despite interventional surgery was 518 days (range, 152 to 1,220 days). Surgical intervention was necessary in 4 dogs to maintain satisfactory IOP. Implant extrusion attributable to conjunctival dehiscence or necrosis occurred in 4 dogs. At 365 days after surgery, 8 dogs retained vision, and 5 dogs retained vision throughout follow-up.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\n                    \u2014In dogs with medically refractory primary glaucoma, placement of a gonioimplant appears to be effective in maintaining vision.\n                  <\/jats:p>","DOI":"10.2460\/javma.238.5.610","type":"journal-article","created":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T14:13:49Z","timestamp":1299075229000},"page":"610-617","source":"Crossref","is-referenced-by-count":36,"title":["Long-term evaluation of the use of Ahmed gonioimplants in dogs with primary glaucoma: nine cases (2000\u20132008)"],"prefix":"10.2460","volume":"238","author":[{"given":"Hans D.","family":"Westermeyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane V. H.","family":"Hendrix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel A.","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Vet Comp Ophthalmol","first-page":"148","article-title":"Diode laser transscleral cyclophotocoagulation for the treatment of glaucoma in dogs: results of six and twelve month follow-up","volume":"7","author":"Cook","year":"1997"},{"key":"ref2","series-title":"Vet Ophthalmol","first-page":"209","article-title":"Diode laser transscleral cyclophotocoagulation for the treatment of primary glaucoma in 18 dogs: a retrospective study","volume":"4","author":"Hardman","year":"2001"},{"key":"ref3","series-title":"Vet Comp Ophthalmol","first-page":"243","article-title":"Implantation of filtering devices in dogs with glaucoma: preliminary results in 13 eyes","volume":"6","author":"Bentley","year":"1996"},{"key":"ref4","series-title":"Prog Vet Comp Ophthalmol","first-page":"59","article-title":"Issues in ophthalmic therapy: the development of anterior chamber shunts for the clinical management of the canine glaucomas","volume":"2","author":"Gelatt","year":"1992"},{"key":"ref5","series-title":"Vet Comp Ophthalmol","first-page":"77","article-title":"Clinical experience with a glaucoma drainage device in dogs","volume":"4","author":"Tinsley","year":"1994"},{"key":"ref6","series-title":"Am J Ophthalmol","first-page":"455","article-title":"Shunt revision versus additional tube shunt implantation after failed tube shunt surgery in refractory glaucoma","volume":"129","author":"Shah","year":"2000"},{"key":"ref7","series-title":"Am J Vet Res","first-page":"936","article-title":"Effects of topically applied mitomycin-C on intraocular pressure, facility of outflow, and fibrosis after glaucoma filtration surgery in clinically normal dogs","volume":"56","author":"Glover","year":"1995"},{"key":"ref8","series-title":"Vet Comp Ophthalmol","first-page":"231","article-title":"In vivo clinical trial of perioperative mitomycin-C in combination with a drainage device implantation in normal canine globes","volume":"5","author":"Tinsley","year":"1995"},{"key":"ref9","series-title":"Ophthalmol Clin North Am","first-page":"501","article-title":"Clinical perspectives on glaucoma-filtering surgery: antiproliferative agents","volume":"13","author":"Adam","year":"2000"},{"key":"ref10","series-title":"Anim Eye Res","first-page":"9","article-title":"Evaluation of valved and nonvalved gonioimplants in 83 eyes of 65 dogs with glaucoma","volume":"17","author":"Garcia-Sanchez","year":"1998"},{"key":"ref11","series-title":"J Small Anim Pract","first-page":"68","article-title":"A clinical evaluation of a one-piece drainage system in the treatment of canine glaucoma","volume":"30","author":"Bedford","year":"1989"},{"key":"ref12","series-title":"J Am Vet Med Assoc","first-page":"1469","article-title":"Combined cycloablation and gonioimplantation for treatment of glaucoma in dogs: 18 cases (1992\u20131998)","volume":"215","author":"Bentley","year":"1999"},{"key":"ref13","series-title":"Vet Ophthalmol","first-page":"121","article-title":"Combined transscleral diode laser cyclophotocoagulation and Ahmed gonioimplantation in dogs with primary glaucoma: 51 cases (1996\u20132004)","volume":"8","author":"Sapienza","year":"2005"},{"key":"ref14","series-title":"Ophthalmology","first-page":"2198","article-title":"Otago glaucoma surgery outcome study: factors controlling capsule fibrosis around Molteno implants with histopathological correlation","volume":"110","author":"Molteno","year":"2003"},{"key":"ref15","series-title":"Vet Ophthalmol","first-page":"311","article-title":"Cullen frontal sinus valved glaucoma shunt: preliminary findings in dogs with primary glaucoma","volume":"7","author":"Cullen","year":"2004"},{"key":"ref16","series-title":"Vet Comp Ophthalmol","first-page":"82","article-title":"Extraorbital diversion of aqueous in the treatment of glaucoma in the dog: a pilot study including two recipient sites","volume":"6","author":"H\u00e5kanson","year":"1996"},{"key":"ref17","series-title":"J Glaucoma","first-page":"233","article-title":"A prospective, comparative study between endoscopic cyclophotocoagulation and the Ahmed drainage implant in refractory glaucoma","volume":"13","author":"Lima","year":"2004"},{"key":"ref18","series-title":"J Glaucoma","first-page":"238","article-title":"Endoscopic and transscleral cyclophotocoagulation for the treatment of refractory glaucoma","volume":"17","author":"Lin","year":"2008"},{"key":"ref19","series-title":"Ophthalmology","first-page":"89","article-title":"Use of temporalis fascia in eyelid reconstruction","volume":"91","author":"Holt","year":"1984"},{"key":"ref20","series-title":"Ophthalmic Surg Lasers","first-page":"403","article-title":"Wrapping hydroxyapatite implants","volume":"30","author":"Jordan","year":"1999"},{"key":"ref21","series-title":"Br J Ophthalmol","first-page":"942","article-title":"Autogenous temporalis fascia patch graft for porous polyethylene (Medpor) sphere orbital implant exposure","volume":"88","author":"Sagoo","year":"2004"},{"key":"ref22","series-title":"Ophthal Plast Reconstr Surg","first-page":"153","article-title":"Temporalis fascia in the management of gold eyelid weight extrusion","volume":"21","author":"Thomas","year":"2005"},{"key":"ref23","series-title":"Ophthalmic Surg","first-page":"472","article-title":"Extrusion of enucleation implants: treatment with secondary implants and autogenous temporalis fascia or fascia lata patch grafts","volume":"23","author":"Wiggs","year":"1992"},{"key":"ref24","series-title":"Cornea","first-page":"537","article-title":"Corneoscleral melt after pterygium surgery using a single intraoperative application of mitomycin-C","volume":"15","author":"Dougherty","year":"1996"},{"key":"ref25","series-title":"Cont Lens Anterior Eye","first-page":"165","article-title":"Scleral melting 16 years after pterygium excision with topical mitomycin C adjuvant therapy","volume":"29","author":"Wan Norliza","year":"2006"},{"key":"ref26","series-title":"Acta Ophthalmol Scand","first-page":"147","article-title":"Intraoperative application versus postoperative mitomycin C eye drops in pterygium surgery","volume":"77","author":"Oguz","year":"1999"},{"key":"ref27","series-title":"Eur J Ophthalmol","first-page":"27","article-title":"The effect of adjunctive mitomycin C in Ahmed glaucoma valve implantation","volume":"15","author":"Kurnaz","year":"2005"},{"key":"ref28","series-title":"Ophthalmology","first-page":"1071","article-title":"Efficacy and safety of adjunctive mitomycin C during Ahmed glaucoma valve implantation: a prospective randomized clinical trial","volume":"111","author":"Costa","year":"2004"},{"key":"ref29","series-title":"Ophthalmic Surg Lasers","first-page":"382","article-title":"Capsule excision after failed Molteno surgery","volume":"28","author":"Valimaki","year":"1997"},{"key":"ref30","series-title":"Ophthalmol Clin North Am","first-page":"517","article-title":"The failing filtering bleb","volume":"13","author":"Palmberg","year":"2000"},{"key":"ref31","series-title":"Vet Ophthalmol","first-page":"139","article-title":"Ahmed valve implantation to control intractable glaucoma after phacoemulsification and intraocular lens implantation in a dog","volume":"8","author":"Garcia-Sanchez","year":"2005"},{"key":"ref32","series-title":"Acta Ophthalmol Scand","first-page":"586","article-title":"Hypotony maculopathy","volume":"85","author":"Costa","year":"2007"},{"key":"ref33","series-title":"Acta Ophthalmol Scand","first-page":"584","article-title":"Ocular hypotony: what is the mechanism of effusion and oedema?","volume":"85","author":"Stef\u00e1nsson","year":"2007"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/238\/5\/javma.238.5.610.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/238\/5\/javma.238.5.610.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/238\/5\/javma.238.5.610.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T08:18:08Z","timestamp":1741335488000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/238\/5\/javma.238.5.610.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,1]]},"references-count":33,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.2460\/javma.238.5.610","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3,1]]}}}