{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T11:53:25Z","timestamp":1792756405961,"version":"4.5.0"},"reference-count":14,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2011,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Objective<\/jats:bold>\n                    \u2014To determine whether mass-to-splenic volume ratio or splenic weight as a percentage of body weight was significantly different between dogs with benign versus malignant splenic masses.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design<\/jats:bold>\n                    \u2014Retrospective case series.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Animals<\/jats:bold>\n                    \u201465 dogs that underwent splenectomy.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Procedures<\/jats:bold>\n                    \u2014Medical records of dogs examined between October 2007 and June 2008 because of a splenic mass were reviewed. Information obtained included dog age, breed, and weight; whether hemoperitoneum was present; splenic weight and dimensions (length, width, and height) at the time of splenectomy; dimensions (length, width, and height) of the splenic mass; and histologic diagnosis. Information on survival time was recorded when available.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    \u201430 (46%) dogs had hemangiosarcoma, 10 (15%) had other types of malignant masses, and 25 (39%) had benign masses. Dogs with benign splenic masses had a significantly higher mean mass-to-splenic volume ratio and higher mean splenic weight as a percentage of body weight than did dogs with hemangiosarcoma.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions and Clinical Relevance<\/jats:bold>\n                    \u2014Results suggested that mass-to-splenic volume ratio and splenic weight as a percentage of body weight may be useful in differentiating between hemangiosarcoma and benign lesions in dogs with splenic masses.\n                  <\/jats:p>","DOI":"10.2460\/javma.239.10.1325","type":"journal-article","created":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T10:46:36Z","timestamp":1320144396000},"page":"1325-1327","source":"Crossref","is-referenced-by-count":47,"title":["Mass-to-splenic volume ratio and splenic weight as a percentage of body weight in dogs with malignant and benign splenic masses: 65 cases (2007\u20132008)"],"prefix":"10.2460","volume":"239","author":[{"given":"Mary Jo","family":"Mallinckrodt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon D.","family":"Gottfried","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"J Vet Intern Med","first-page":"166","article-title":"Pathologic factors affecting postsplenectomy survival in dogs","volume":"11","author":"Spangler","year":"1997"},{"key":"ref2","series-title":"J Vet Intern Med","first-page":"160","article-title":"Splenomegaly in dogs, predictors of neoplasia and survival after splenectomy","volume":"3","author":"Johnson","year":"1989"},{"key":"ref3","series-title":"J Am Anim Hosp Assoc","first-page":"417","article-title":"Prognosis for dogs with stage I or II splenic hemangiosarcoma treated by splenectomy alone: 32 cases (1991\u20131993)","volume":"34","author":"Wood","year":"1998"},{"key":"ref4","series-title":"J Am Vet Med Assoc","first-page":"829","article-title":"Prevalence, type and importance of splenic disease in dogs: 1,480 cases (1985\u20131989)","volume":"200","author":"Spangler","year":"1992"},{"key":"ref5","series-title":"Vet Radiol Ultrasound","first-page":"154","article-title":"Use of contrast-enhanced ultrasound for characterization of focal splenic lesions","volume":"49","author":"Rossi","year":"2008"},{"key":"ref6","series-title":"J Am Vet Med Assoc","first-page":"88","article-title":"Contrast harmonic ultrasonography of splenic masses and associated liver nodules in dogs","volume":"234","author":"Ivancic","year":"2009"},{"key":"ref7","series-title":"Vet Radiol Ultrasound","first-page":"289","article-title":"Comparison between malignant and nonmalignant splenic masses in dogs using contrast-enhanced computed tomography","volume":"45","author":"Fife","year":"2004"},{"key":"ref8","series-title":"J Vet Intern Med","first-page":"102","article-title":"Fine-needle aspiration of the spleen as an aid in the diagnosis of splenomegaly","volume":"1","author":"O'Keefe","year":"1987"},{"key":"ref9","series-title":"J Am Vet Med Assoc","first-page":"553","article-title":"Prevalence of hemangiosarcoma in anemic dogs with a splenic mass and hemoperitoneum requiring a transfusion: 71 cases (2003\u20132005)","volume":"232","author":"Hammond","year":"2008"},{"key":"ref10","series-title":"J Small Anim Pract","first-page":"426","article-title":"A review of pathological diagnoses made from 87 canine splenic biopsies","volume":"36","author":"Day","year":"1995"},{"key":"ref11","series-title":"J Am Anim Hosp Assoc","first-page":"72","article-title":"Prognosis for acute non-traumatic hemoperitoneum in the dog: a retrospective analysis of 60 cases (2003\u20132006)","volume":"45","author":"Aronsohn","year":"2009"},{"key":"ref12","series-title":"J Am Vet Med Assoc","first-page":"706","article-title":"Epidemiologic, clinical, pathologic, and prognostic characteristics of splenic hemangiosarcoma and splenic hematoma in dogs: 217 cases (1985)","volume":"193","author":"Prymak","year":"1988"},{"key":"ref13","series-title":"Compend Contin Educ Pract Vet","first-page":"452","article-title":"Deracoxib","volume":"25","author":"Smith","year":"2003"},{"key":"ref14","series-title":"Vet Anaesth Analg","first-page":"102","article-title":"The effect of four anesthetic protocols on splenic size in dogs","volume":"31","author":"Wilson","year":"2004"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/239\/10\/javma.239.10.1325.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/239\/10\/javma.239.10.1325.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/239\/10\/javma.239.10.1325.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T08:46:57Z","timestamp":1741337217000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/239\/10\/javma.239.10.1325.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,15]]},"references-count":14,"journal-issue":{"issue":"10"},"URL":"https:\/\/doi.org\/10.2460\/javma.239.10.1325","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11,15]]}}}