{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:51:18Z","timestamp":1758635478322,"version":"3.38.0"},"reference-count":22,"publisher":"American Veterinary Medical Association (AVMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2011,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p><jats:bold>Case Description<\/jats:bold>\u2014A 6-year-old neutered male cat was examined because of a 4-week history of abnormal sounds while drinking and a previously noted mass at the base of the tongue.<\/jats:p>\n<jats:p><jats:bold>Clinical Findings<\/jats:bold>\u2014Oral examination revealed a 1-cm-diameter midline cystic mass on the dorsal aspect of the base of the tongue at the junction of the rostral two-thirds and caudal third of the tongue. Complete blood count and serum biochemical analysis revealed no clinically relevant abnormalities, and serum total thyroxine and free thyroxine (determined by equilibrium dialysis) concentrations were within the reference range.<\/jats:p>\n<jats:p><jats:bold>Treatment and Outcome<\/jats:bold>\u2014The fluid in the cystic mass was aspirated, and the remaining deflated mass was marsupialized. Histologic and immunohistochemical examination of sections of the excised mass revealed ectopic thyroid tissue. The cat recovered uneventfully from the surgery, clinical signs resolved, and the cat remained euthyroid with no recurrence of the mass as of 8 months after surgery.<\/jats:p>\n<jats:p><jats:bold>Clinical Relevance<\/jats:bold>\u2014This is the first known reported case of ectopic lingual thyroid tissue in a male cat. In humans, the most common site of ectopic thyroid tissue is at the base of the tongue and the condition is disproportionately found in females, compared with males. In humans with ectopic lingual thyroid tissue, the patient often lacks any other functional thyroid tissue. However, the cat of this report remained euthyroid after mass resection.<\/jats:p>","DOI":"10.2460\/javma.239.7.981","type":"journal-article","created":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T07:04:09Z","timestamp":1317452649000},"page":"981-984","source":"Crossref","is-referenced-by-count":9,"title":["Cystic ectopic lingual thyroid tissue in a male cat"],"prefix":"10.2460","volume":"239","author":[{"given":"Travis P.","family":"Reed","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigitte A.","family":"Brisson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leah K.","family":"Schutt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Pathologica","first-page":"640","article-title":"Expression of thyroid transcription factor 1 (TTF-1) in extra thyroidal sites: papillary thyroid carcinoma of branchial cleft cysts and thyroglossal duct cysts and struma ovarii","volume":"98","author":"Lanzafame","year":"2006"},{"key":"ref2","series-title":"Tumori","first-page":"517","article-title":"Immunohistochemical markers of thyroid tumors: significance and diagnostic applications","volume":"89","author":"Rosai","year":"2003"},{"key":"ref3","series-title":"Vet Pathol","first-page":"480","article-title":"Immunohistochemical detection of thyroid transcription factor-1, thyroglobulin, and calcitonin in canine normal, hyperplastic, and neoplastic thyroid gland","volume":"39","author":"Ramos-Vara","year":"2002"},{"key":"ref4","series-title":"J Laryngol Otol","first-page":"71","article-title":"Evidence for thyroid development from the fourth brachial pouch","volume":"108","author":"Ohri","year":"1994"},{"key":"ref5","series-title":"J Feline Med Surg","first-page":"143","article-title":"Ectopic lingual thyroid tissue in a cat","volume":"2","author":"Patnaik","year":"2000"},{"key":"ref6","series-title":"Vet Surg","first-page":"287","article-title":"Results of thyroidectomy in 101 cats with hyperthyroidism","volume":"35","author":"Naan","year":"2006"},{"key":"ref7","series-title":"J Feline Med Surg","first-page":"96","article-title":"Scintigraphic findings in 120 hyperthyroid cats","volume":"11","author":"Harvey","year":"2009"},{"key":"ref8","series-title":"Br Vet J","first-page":"669","article-title":"A case report and review: the gross, histological and immunohistochemical characteristics of a carcinoma of ectopic thyroid in a dog","volume":"12","author":"Constantino-Casas","year":"1996"},{"key":"ref9","series-title":"Vet Pathol","first-page":"669","article-title":"Ectopic thyroid carcinoma with metastases in a Beagle dog","volume":"19","author":"Stephens","year":"1982"},{"key":"ref10","series-title":"Head Neck","first-page":"87","article-title":"Ectopic thyroid tissue presenting as a submandibular mass","volume":"18","author":"Sambola-Cabrer","year":"1996"},{"key":"ref11","series-title":"J Laryngol Otol","first-page":"673","article-title":"Intralaryngotracheal thyroid\u2014ectopic thyroid or invasive carcinoma?","volume":"112","author":"See","year":"1998"},{"key":"ref12","series-title":"Ear Nose Throat J","first-page":"340","article-title":"Lingual thyroid gland: clinical evaluation and comprehensive management","volume":"78","author":"Kalan","year":"1999"},{"key":"ref13","series-title":"Surg Today","first-page":"472","article-title":"Ectopic thyroid in the abdomen: report of a case","volume":"29","author":"Ey\u00fcbo\u011flu","year":"1999"},{"key":"ref14","series-title":"Hum Pathol","first-page":"105","article-title":"Ectopic thyroid in the adrenal gland","volume":"30","author":"Shiraishi","year":"1999"},{"key":"ref15","series-title":"J Laryngol Otol","first-page":"393","article-title":"Dual ectopic thyroid: a report of two cases","volume":"112","author":"Hazarika","year":"1998"},{"key":"ref16","series-title":"Hum Pathol","first-page":"187","article-title":"Clonal analysis help to differentiate aberrant thyroid tissue from thyroid carcinoma","volume":"29","author":"Kakudo","year":"1998"},{"key":"ref17","series-title":"Otolaryngol Head Neck Surg","first-page":"483","article-title":"Lingual thyroid","volume":"155","author":"Akyol","year":"1996"},{"key":"ref18","series-title":"Laryngoscope","first-page":"1174","article-title":"Lingual thyroid in children: a rare clinical entity","volume":"118","author":"Rahbar","year":"2008"},{"key":"ref19","series-title":"Ann Otol Rhinol Laryngol","first-page":"996","article-title":"Thyroid gland ectopias","volume":"105","author":"Batsakis","year":"1996"},{"key":"ref20","series-title":"Acta Otorhinolaryngol Ital","first-page":"213","article-title":"Lingual thyroid causing dysphagia and dysphonia. Case reports and review of the literature","volume":"29","author":"Toso","year":"2009"},{"key":"ref21","series-title":"Arch Intern Med","first-page":"2036","article-title":"Lingual thyroid: diagnosis and treatment","volume":"147","author":"Kansal","year":"1987"},{"key":"ref22","series-title":"J Am Vet Med Assoc","first-page":"529","article-title":"Measurement of serum concentrations of free thyroxine, total thyroxine, and total triiodothyronine in cats with hyperthyroidism and cats with nonthyroidal disease","volume":"218","author":"Peterson","year":"2001"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/239\/7\/javma.239.7.981.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/239\/7\/javma.239.7.981.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/239\/7\/javma.239.7.981.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:46:35Z","timestamp":1741355195000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/239\/7\/javma.239.7.981.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,1]]},"references-count":22,"journal-issue":{"issue":"7"},"URL":"https:\/\/doi.org\/10.2460\/javma.239.7.981","relation":{},"ISSN":["0003-1488"],"issn-type":[{"type":"print","value":"0003-1488"}],"subject":[],"published":{"date-parts":[[2011,10,1]]}}}