{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T09:47:28Z","timestamp":1789379248956,"version":"build-2803163510"},"reference-count":4,"publisher":"American Veterinary Medical Association (AVMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To report a novel presentation of feline hemangiosarcoma.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>ANIMALS<\/jats:title>\n<jats:p>A 14-year-old spayed female feline patient diagnosed with hemangiosarcoma of the spleen and a cervical lymph node.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES<\/jats:title>\n<jats:p>The patient presented to the emergency service following a 1-week history of lethargy and hiding. Abdominal ultrasound revealed splenomegaly with multiple nodules and peritoneal fluid that was consistent with hemorrhagic effusion.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>TREATMENT AND OUTCOME<\/jats:title>\n<jats:p>The patient underwent a routine splenectomy and was started on doxorubicin. Histopathologic evaluation of the spleen confirmed visceral hemangiosarcoma. When the disease showed signs of progression, combination chemotherapy with cyclophosphamide and vincristine was initiated. Four months following presentation, a submandibular lymph node was removed and found to have metastatic hemangiosarcoma. From presentation to euthanasia, the patient survived 205 days.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>Hemangiosarcoma is a rare cancer in feline patients, with a lack of veterinary literature on its presentation and chemotherapy protocols. The subject of this case report had a novel presentation of hemangiosarcoma and responded favorably to a chemotherapy protocol not previously described for this disease.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.24.01.0015","type":"journal-article","created":{"date-parts":[[2024,3,11]],"date-time":"2024-03-11T12:12:16Z","timestamp":1710159136000},"page":"1-3","source":"Crossref","is-referenced-by-count":1,"title":["Novel presentation of a feline patient with visceral and cervical lymph node hemangiosarcoma"],"prefix":"10.2460","volume":"262","author":[{"given":"Alexandra","family":"Goddard","sequence":"first","affiliation":[{"name":"WestVet Boise 24\/7 Animal Emergency & Specialty Center, Boise, ID"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine","family":"Walters","sequence":"additional","affiliation":[{"name":"WestVet Boise 24\/7 Animal Emergency & Specialty Center, Boise, ID"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy","family":"Campbell","sequence":"additional","affiliation":[{"name":"WestVet Boise 24\/7 Animal Emergency & Specialty Center, Boise, ID"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1272","reference":[{"issue":"12","key":"ref1","series-title":"J Am Vet Med Assoc","first-page":"1851","article-title":"Hemangiosarcoma in cats: 53 cases (1992\u20132002)","volume":"231","author":"Johannes CM","year":"2007","unstructured":"Johannes CM, Henry CJ, Turnquist SE,  Hemangiosarcoma in cats: 53 cases (1992\u20132002). J Am Vet Med Assoc. 2007; 231(12):1851-1856. doi:10.2460\/javma.231.12.1851"},{"issue":"9","key":"ref2","series-title":"Vet Rec","first-page":"e585","article-title":"Canine and feline haemangiosarcoma","volume":"189","author":"Griffin MA","year":"2021","unstructured":"Griffin MA, Culp WTN, Rebhun RB. Canine and feline haemangiosarcoma. Vet Rec. 2021;189(9):e585. doi:10.1002\/vetr.585"},{"issue":"1","key":"ref3","series-title":"J Vet Intern Med","first-page":"148","article-title":"Feline visceral hemangiosarcoma","volume":"22","author":"Culp WT","year":"2008","unstructured":"Culp WT, Drobatz KJ, Glassman MM, Baez JL, Aronson LR. Feline visceral hemangiosarcoma. J Vet Intern Med. 2008; 22(1):148-152. doi:10.1111\/j.1939-1676.2008.0022.x"},{"issue":"2","key":"ref4","series-title":"Vet Pathol","first-page":"331","article-title":"Histology and clinical outcome of benign and malignant vascular lesions primary to feline cervical lymph nodes","volume":"52","author":"Roof-Wages E","year":"2015","unstructured":"Roof-Wages E, Spangler T, Spangler WL, Siedlecki CT. Histology and clinical outcome of benign and malignant vascular lesions primary to feline cervical lymph nodes. Vet Pathol. 2015; 52(2):331-337. doi:10.1177\/0300985814537528"}],"container-title":["Journal of the American Veterinary Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/262\/5\/javma.24.01.0015.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/262\/5\/javma.24.01.0015.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/avmajournals.avma.org\/downloadpdf\/journals\/javma\/262\/5\/javma.24.01.0015.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T13:05:55Z","timestamp":1741352755000},"score":1,"resource":{"primary":{"URL":"https:\/\/avmajournals.avma.org\/view\/journals\/javma\/262\/5\/javma.24.01.0015.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,1]]},"references-count":4,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.2460\/javma.24.01.0015","relation":{},"ISSN":["0003-1488"],"issn-type":[{"value":"0003-1488","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5,1]]}}}