{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T08:11:07Z","timestamp":1747210267299,"version":"3.40.5"},"reference-count":30,"publisher":"American Veterinary Medical Association (AVMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["javma"],"published-print":{"date-parts":[[2024,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>To determine whether subtotal pericardectomy affects recurrence and long-term outcomes in dogs with idiopathic chylothorax (IC).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>ANIMALS<\/jats:title>\n<jats:p>12 client-owned dogs diagnosed with IC between July 26, 2016, and March 23, 2023.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>The diagnosis of constrictive physiology (CP) was established with cardiac catheterization and defined as elevated and equal diastolic pressures in all 4 cardiac chambers. Dogs were then entered into the constrictive physiology (CP) group or non-CP (NCP) group. All dogs received at least a thoracic duct ligation (TDL). The dogs in the CP group had a subtotal pericardectomy performed in addition to TDL. Repeated surgical interventions, recurrence, long-term outcomes, and survival times were recorded.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>8 dogs were entered into the CP group and underwent TDL and subtotal pericardectomy. Four dogs were entered in the NCP group and underwent only a TDL. Four dogs in the CP group and 1 in the NCP group required multiple surgeries for recurrent chylothorax. The 1-, 2-, and 3-year disease-free rates were, respectively, 100%, 100%, and 50% for the NCP group and 87.5%, 72.9%, and 72.9% for the CP group (<jats:italic>P<\/jats:italic> = .935). The 1-, 2-, and 3-year survival rates were, respectively, 100%, 100%, and 100% for the NCP group and 87.5%, 72.9%, and 72.9% for the CP group (<jats:italic>P<\/jats:italic> = .317).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>CLINICAL RELEVANCE<\/jats:title>\n<jats:p>Constrictive physiology should be evaluated by cardiac catheterization before surgical treatment of IC in dogs. If CP is not diagnosed, subtotal pericardectomy may not be required.<\/jats:p>\n<\/jats:sec>","DOI":"10.2460\/javma.24.02.0124","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T16:35:54Z","timestamp":1716395754000},"page":"1354-1362","source":"Crossref","is-referenced-by-count":0,"title":["Constrictive physiology is not present in all dogs with idiopathic chylothorax"],"prefix":"10.2460","volume":"262","author":[{"given":"Taylor E.","family":"Adams","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah J.","family":"Marvel","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0058-2210","authenticated-orcid":true,"given":"Eric","family":"Monnet","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1272","reference":[{"key":"ref1","series-title":"Small Animal Soft Tissue Surgery","first-page":"375","article-title":"Chylothorax","author":"McAnulty JF","year":"2023","unstructured":"McAnulty JF. Chylothorax. In Monnet E, ed. Small Animal Soft Tissue Surgery. 2nd ed. Wiley-Blackwell; 2023:375-391."},{"issue":"8","key":"ref2","series-title":"Vet Surg","first-page":"926","article-title":"Prospective comparison of cisterna chyli ablation to pericardectomy for treatment of spontaneously occurring idiopathic chylothorax in the dog","volume":"40","author":"McAnulty JF","year":"2011","unstructured":"McAnulty JF. Prospective comparison of cisterna chyli ablation to pericardectomy for treatment of spontaneously occurring idiopathic chylothorax in the dog. Vet Surg. 2011;40(8):926-934. doi:10.1111\/j.1532-950X.2011.00902.x"},{"issue":"1","key":"ref3","series-title":"Vet Surg","first-page":"70","article-title":"Treatment of idiopathic chylothorax in dogs and cats: a systematic review","volume":"49","author":"Reeves LA","year":"2020","unstructured":"Reeves LA, Anderson KM, Luther JK, Torres BT. Treatment of idiopathic chylothorax in dogs and cats: a systematic review. Vet Surg. 2020;49(1):70-79. doi:10.1111\/vsu.13322"},{"issue":"2","key":"ref4","series-title":"Vet Surg","first-page":"138","article-title":"Thoracoscopic visualization and ligation of the thoracic duct in dogs","volume":"31","author":"Radlinsky MG","year":"2002","unstructured":"Radlinsky MG, Mason DE, Biller DS, Olsen D. Thoracoscopic visualization and ligation of the thoracic duct in dogs. Vet Surg. 2002;31(2):138-146. doi:10.1053\/jvet.2002.31062"},{"issue":"1","key":"ref5","series-title":"Vet Surg","first-page":"21","article-title":"Thoracoscopic thoracic duct ligation and thoracoscopic pericardectomy for treatment of chylothorax in dogs","volume":"39","author":"Allman DA","year":"2010","unstructured":"Allman DA, Radlinsky MG, Ralph AG, Rawlings CA. Thoracoscopic thoracic duct ligation and thoracoscopic pericardectomy for treatment of chylothorax in dogs. Vet Surg. 2010;39(1):21-27. doi:10.1111\/j.1532-950X.2009.00623.x"},{"issue":"S1","key":"ref6","series-title":"Vet Surg","first-page":"O112","article-title":"Long-term outcome of video-assisted thoracoscopic thoracic duct ligation and pericardectomy in dogs with chylothorax: a multi-institutional study of 39 cases","volume":"48","author":"Mayhew PD","year":"2019","unstructured":"Mayhew PD, Steffey MA, Fransson BA,  Long-term outcome of video-assisted thoracoscopic thoracic duct ligation and pericardectomy in dogs with chylothorax: a multi-institutional study of 39 cases. Vet Surg. 2019;48(S1):O112-O120. doi:10.1111\/vsu.13113"},{"issue":"1","key":"ref7","series-title":"J Am Vet Med Assoc","first-page":"107","article-title":"Long-term outcome of dogs treated surgically for idiopathic chylothorax: 11 cases (1995-2009)","volume":"239","author":"da Silva CA","year":"2011","unstructured":"da Silva CA, Monnet E. Long-term outcome of dogs treated surgically for idiopathic chylothorax: 11 cases (1995-2009). J Am Vet Med Assoc. 2011;239(1):107-113. doi:10.2460\/javma.239.1.107"},{"issue":"8","key":"ref8","series-title":"J Vet Med Sci","first-page":"1079","article-title":"Triple-combination surgery with thoracic duct ligation, partial pericardiectomy, and cisterna chyli ablation for treatment of canine idiopathic chylothorax","volume":"84","author":"Ishigaki K","year":"2022","unstructured":"Ishigaki K, Nagumo T, Sakurai N, Asano K. Triple-combination surgery with thoracic duct ligation, partial pericardiectomy, and cisterna chyli ablation for treatment of canine idiopathic chylothorax. J Vet Med Sci. 2022;84(8):1079-1083. doi:10.1292\/jvms.22-0043"},{"issue":"suppl 1","key":"ref9","series-title":"Vet Surg","first-page":"O102","article-title":"Efficacy of en bloc thoracic duct ligation in combination with pericardiectomy by video-assisted thoracoscopic surgery for canine idiopathic chylothorax","volume":"49","author":"Kanai H","year":"2020","unstructured":"Kanai H, Furuya M, Hagiwara K,  Efficacy of en bloc thoracic duct ligation in combination with pericardiectomy by video-assisted thoracoscopic surgery for canine idiopathic chylothorax. Vet Surg. 2020;49(suppl 1):O102-O111. doi:10.1111\/vsu.13370"},{"issue":"3","key":"ref10","series-title":"J Vet Intern Med","first-page":"307","article-title":"Thoracic duct ligation and pericardectomy for treatment of idiopathic chylothorax","volume":"18","author":"Fossum TW","year":"2004","unstructured":"Fossum TW, Mertens MM, Miller MW,  Thoracic duct ligation and pericardectomy for treatment of idiopathic chylothorax. J Vet Intern Med. 2004;18(3):307-310. doi:10.1892\/0891-6640(2004)18<307:tdlapf>2.0.co;2"},{"issue":"6","key":"ref11","series-title":"J Am Coll Cardiol","first-page":"1164","article-title":"Diagnosis of constrictive pericarditis by two-dimensional echocardiography: studies in a new experimental model and in patients","volume":"4","author":"Pandian NG","year":"1984","unstructured":"Pandian NG, Skorton DJ, Kieso RA, Kerber RE. Diagnosis of constrictive pericarditis by two-dimensional echocardiography: studies in a new experimental model and in patients. J Am Coll Cardiol. 1984;4(6):1164-1173. doi:10.1016\/s0735-1097(84)80134-5"},{"issue":"3","key":"ref12","series-title":"G Ital Cardiol (Rome)","first-page":"197","article-title":"Inquadramento e gestione della pericardite costrittiva: revisione critica","volume":"17","author":"Pinamonti B","year":"2016","unstructured":"Pinamonti B, Habjan S, De Luca A,  Inquadramento e gestione della pericardite costrittiva: revisione critica. G Ital Cardiol (Rome). 2016;17(3):197-207."},{"key":"ref13","series-title":"Textbook of Canine and Feline Cardiology; Principles and Clinical Practice","first-page":"679","article-title":"Pericardial disease and cardiac tumors","author":"Sisson D","year":"1999","unstructured":"Sisson D, Thomas WP. Pericardial disease and cardiac tumors. In: Fox PR, Sisson D, Moise NS, eds. Textbook of Canine and Feline Cardiology; Principles and Clinical Practice. 2nd ed. Saunders; 1999:679-701."},{"key":"ref14","series-title":"Braunwald\u2019s Heart Disease: A Textbook of Cardiovascular Medicine","first-page":"1662","article-title":"Pericardial diseases","author":"Lewinter MM","year":"2019","unstructured":"Lewinter MM, Imazio M. Pericardial diseases. In: Mann DL, Zipes DP, Braunwald E, Tomaselli GF, Libby P, Bonow RO, eds. Braunwald\u2019s Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Elsevier; 2019:1662-1680."},{"issue":"4","key":"ref15","series-title":"Cardiol Clin","first-page":"539","article-title":"Constrictive pericarditis","volume":"35","author":"Welch TD","year":"2017","unstructured":"Welch TD, Oh JK. Constrictive pericarditis. Cardiol Clin. 2017;35(4):539-549. doi:10.1016\/j.ccl.2017.07.007"},{"issue":"5","key":"ref16","series-title":"J Am Vet Med Assoc","first-page":"696","article-title":"Resolution, recurrence, and chyle redistribution after thoracic duct ligation with or without pericardiectomy in dogs with naturally occurring idiopathic chylothorax","volume":"261","author":"Mayhew PD","year":"2022","unstructured":"Mayhew PD, Balsa IM, Stern JA,  Resolution, recurrence, and chyle redistribution after thoracic duct ligation with or without pericardiectomy in dogs with naturally occurring idiopathic chylothorax. J Am Vet Med Assoc. 2022;261(5):696-704. doi:10.2460\/javma.22.08.0381"},{"issue":"suppl 1","key":"ref17","series-title":"Vet Surg","first-page":"O128","article-title":"Prospective evaluation of lymphatic embolization as part of the treatment in dogs with presumptive idiopathic chylothorax","volume":"51","author":"Carvajal JL","year":"2022","unstructured":"Carvajal JL, Case JB, Vilaplana Grosso FR,  Prospective evaluation of lymphatic embolization as part of the treatment in dogs with presumptive idiopathic chylothorax. Vet Surg. 2022;51(suppl 1):O128-O137. doi:10.1111\/vsu.13825"},{"issue":"S1","key":"ref18","series-title":"Vet Surg","first-page":"O121","article-title":"Hybrid single-port laparoscopic cisterna chyli ablation for the adjunct treatment of chylothorax disease in dogs","volume":"48","author":"Morris KP","year":"2019","unstructured":"Morris KP, Singh A, Holt DE,  Hybrid single-port laparoscopic cisterna chyli ablation for the adjunct treatment of chylothorax disease in dogs. Vet Surg. 2019;48(S1):O121-O129. doi:10.1111\/vsu.13195"},{"issue":"2","key":"ref19","series-title":"Vet Surg","first-page":"267","article-title":"Use of direct near-infrared fluorescent lymphography for thoracoscopic thoracic duct identification in 15 dogs with chylothorax","volume":"47","author":"Steffey MA","year":"2018","unstructured":"Steffey MA, Mayhew PD. Use of direct near-infrared fluorescent lymphography for thoracoscopic thoracic duct identification in 15 dogs with chylothorax. Vet Surg. 2018;47(2):267-276. doi:10.1111\/vsu.12740"},{"issue":"7","key":"ref20","series-title":"Vet Surg","first-page":"786","article-title":"Single paracostal approach to thoracic duct and cisterna chyli: experimental study and case series","volume":"40","author":"Staiger BA","year":"2011","unstructured":"Staiger BA, Stanley BJ, McAnulty JF. Single paracostal approach to thoracic duct and cisterna chyli: experimental study and case series. Vet Surg. 2011;40(7):786-794. doi:10.1111\/j.1532-950X.2011.00878.x"},{"issue":"5","key":"ref21","series-title":"Vet Surg","first-page":"519","article-title":"Cisterna chyli ablation with thoracic duct ligation for chylothorax: results in eight dogs","volume":"34","author":"Hayashi K","year":"2005","unstructured":"Hayashi K, Sicard G, Gellasch K, Frank JD, Hardie RJ, McAnulty JF. Cisterna chyli ablation with thoracic duct ligation for chylothorax: results in eight dogs. Vet Surg. 2005;34(5):519-523. doi:10.1111\/j.1532-950X.2005.00078.x"},{"issue":"4","key":"ref22","series-title":"Vet Surg","first-page":"611","article-title":"The development of ventricular fibrillation as a complication of pericardiectomy in 16 dogs","volume":"51","author":"Raleigh JS","year":"2022","unstructured":"Raleigh JS, Mayhew PD, Visser LC,  The development of ventricular fibrillation as a complication of pericardiectomy in 16 dogs. Vet Surg. 2022;51(4):611-619. doi:10.1111\/vsu.13795"},{"issue":"15","key":"ref23","series-title":"Circulation","first-page":"1852","article-title":"Constrictive pericarditis in 26 patients with histologically normal pericardial thickness","volume":"108","author":"Talreja DR","year":"2003","unstructured":"Talreja DR, Edwards WD, Danielson GK,  Constrictive pericarditis in 26 patients with histologically normal pericardial thickness. Circulation. 2003;108(15):1852-1857. doi:10.1161\/01.CIR.0000087606.18453.FD"},{"key":"ref24","series-title":"Pleural Disease","first-page":"412","article-title":"Chylothorax and pseudochylothorax","author":"Light RW","year":"2013","unstructured":"Light RW. Chylothorax and pseudochylothorax. In: Light RW, ed. Pleural Disease. 6th ed. Lippincott Williams & Wilkins; 2013:412-430."},{"issue":"48","key":"ref25","series-title":"Dtsch Arztebl Int","first-page":"819","article-title":"Treatment options in patients with chylothorax","volume":"110","author":"Schild HH","year":"2013","unstructured":"Schild HH, Strassburg CP, Welz A, Kalff J. Treatment options in patients with chylothorax. Dtsch Arztebl Int. 2013;110(48):819-826."},{"issue":"2","key":"ref26","series-title":"Eur J Cardiothorac Surg","first-page":"362","article-title":"Aetiology and management of chylothorax in adults","volume":"32","author":"Nair SK","year":"2007","unstructured":"Nair SK, Petko M, Hayward MP. Aetiology and management of chylothorax in adults. Eur J Cardiothorac Surg. 2007;32(2):362-369. doi:10.1016\/j.ejcts.2007.04.024"},{"key":"ref27","series-title":"Small Animal Thoracic Surgery","first-page":"147","article-title":"Pericardium","author":"Monnet E","year":"2017","unstructured":"Monnet E, Orton EC. Pericardium. In: Monnet E, Orton EC, eds. Small Animal Thoracic Surgery. John Wiley & Sons, Inc; 2017:147-158. doi:10.1002\/9781118943427.ch17"},{"issue":"1","key":"ref28","series-title":"Vet Surg","first-page":"21","article-title":"Thoracoscopic pericardectomy performed without pulmonary exclusion in 9 dogs","volume":"30","author":"Dupr\u00e9 GP","year":"2001","unstructured":"Dupr\u00e9 GP, Corlouer JP, Bouvy B. Thoracoscopic pericardectomy performed without pulmonary exclusion in 9 dogs. Vet Surg. 2001;30(1):21-27. doi:10.1053\/jvet.2001.20344"},{"issue":"5","key":"ref29","series-title":"Vet Radiol Ultrasound","first-page":"391","article-title":"Comparison of radiographic and computed tomography lymphangiography for identification of the canine thoracic duct","volume":"46","author":"Esterline ML","year":"2005","unstructured":"Esterline ML, Radlinsky MG, Biller DS, Mason DE, Roush JK, Cash WC. Comparison of radiographic and computed tomography lymphangiography for identification of the canine thoracic duct. Vet Radiol Ultrasound. 2005;46(5):391-395. doi:10.1111\/j.1740-8261.2005.00071.x"},{"issue":"7","key":"ref30","series-title":"Vet Surg","first-page":"696","article-title":"Efficacy of en bloc ligation of the thoracic duct: descriptive study in 14 dogs","volume":"37","author":"MacDonald NJ","year":"2008","unstructured":"MacDonald NJ, Noble PJ, Burrow RD. Efficacy of en bloc ligation of the thoracic duct: descriptive study in 14 dogs. 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